Search Results - "Chih‐Yang, Huang"
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Supercritical CO2‐Assisted SiOx/Carbon Multi‐Layer Coating on Si Anode for Lithium‐Ion Batteries
Published in Advanced functional materials (01-10-2021)“…Supercritical CO2 (SCCO2), characterized by gas‐like diffusivity, low surface tension, and excellent mass transfer properties, is applied to create a…”
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A review on the effects of current chemotherapy drugs and natural agents in treating non-small cell lung cancer
Published in Biomedicine (Taipei) (01-12-2017)“…Lung cancer is the leading cause of cancer deaths worldwide, and this makes it an attractive disease to review and possibly improve therapeutic treatment…”
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Dual inhibition of TGFβ signaling and CSF1/CSF1R reprograms tumor-infiltrating macrophages and improves response to chemotherapy via suppressing PD-L1
Published in Cancer letters (01-09-2022)“…TGFβ contributes to chemoresistance in advanced colorectal cancer (CRC) via diverse immune-microenvironment mechanisms. Here, we found that cancer cell…”
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Oxaliplatin resistance in colorectal cancer cells is mediated via activation of ABCG2 to alleviate ER stress induced apoptosis
Published in Journal of cellular physiology (01-07-2018)“…Oxaliplatin (OXA), is a third generation platinum drug used as first‐line chemotherapy in colorectal cancer (CRC). Cancer cells acquires resistance to…”
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5
The multifaceted link between inflammation and human diseases
Published in Journal of cellular physiology (01-09-2018)“…Increasing reports on epidemiological, diagnostic, and clinical studies suggest that dysfunction of the inflammatory reaction results in chronic illnesses such…”
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Neferine ameliorates cardiomyoblast apoptosis induced by doxorubicin: possible role in modulating NADPH oxidase/ROS-mediated NFκB redox signaling cascade
Published in Scientific reports (25-09-2017)“…Doxorubicin (DOX) mediated cardiomyopathy is a major challenge in cancer chemotherapy. Redox-cycling of doxorubicin by flavoenzymes makes the heart more…”
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Galangin Reverses H2O2-Induced Dermal Fibroblast Senescence via SIRT1-PGC-1α/Nrf2 Signaling
Published in International journal of molecular sciences (01-02-2022)“…UV radiation and H2O2 are the primary factors that cause skin aging. Both trigger oxidative stress and cellular aging. It has been reported that deacetylase…”
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Atomistic insights into highly active reconstructed edges of monolayer 2H-WSe2 photocatalyst
Published in Nature communications (10-03-2022)“…Ascertaining the function of in-plane intrinsic defects and edge atoms is necessary for developing efficient low-dimensional photocatalysts. We report the…”
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Neferine modulates IGF‐1R/Nrf2 signaling in doxorubicin treated H9c2 cardiomyoblasts
Published in Journal of cellular biochemistry (01-02-2018)“…Doxorubicin (DOX) induced cardiotoxicity is a major problem during chemotherapy of cancers. DOX‐mediated suppression of type 1 IGF receptor (IGF‐1R) signaling…”
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Neferine attenuates doxorubicin‐induced fibrosis and hypertrophy in H9c2 cells
Published in Journal of biochemical and molecular toxicology (01-07-2022)“…Doxorubicin (DOX), an anthracycline antineoplastic candidate is used to treat various malignancies. Around 41% of patients undergoing DOX treatment develop…”
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Detailed insight on β-adrenoceptors as therapeutic targets
Published in Biomedicine & pharmacotherapy (01-09-2019)“…•Adrenoceptors play a crucial role in cardiovascular and pulmonary functions.•β-adrenoceptors is best characterized GPCRs and plays unique features as drug…”
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In Situ TEM Observation of (Cr, Mn, Fe, Co, and Ni)3O4 High‐Entropy Spinel Oxide Formation During Calcination at Atomic Scale
Published in Small (Weinheim an der Bergstrasse, Germany) (01-04-2024)“…High‐entropy oxides (HEOs) are promising anode materials for lithium‐ion batteries (LIBs), owing to their stable crystal structure, superionic conductivity,…”
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Phosphorylation of PDHA by AMPK Drives TCA Cycle to Promote Cancer Metastasis
Published in Molecular cell (15-10-2020)“…Cancer metastasis accounts for the major cause of cancer-related deaths. How disseminated cancer cells cope with hostile microenvironments in secondary site…”
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CXCL2/CXCR2 axis induces cancer stem cell characteristics in CPT‐11‐resistant LoVo colon cancer cells via Gαi‐2 and Gαq/11
Published in Journal of cellular physiology (01-07-2019)“…Cancer stem cells (CSCs) exist in colon cancer and exhibit characteristics of stem cells which are due to lineages of tissues where they arise. Epithelial to…”
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Antioxidant Sirt1/Akt axis expression in resveratrol pretreated adipose‐derived stem cells increases regenerative capability in a rat model with cardiomyopathy induced by diabetes mellitus
Published in Journal of cellular physiology (01-06-2021)“…High‐glucose (HG) suppresses mesenchymal stem cell (MSC) functions, resulting in a decrease in cardiac regenerative capability for MSC in diabetes mellitus…”
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An updated review on pharmacological properties of neferine—A bisbenzylisoquinoline alkaloid from Nelumbo nucifera
Published in Journal of food biochemistry (01-12-2021)“…Phytochemicals have recently received a lot of recognition for their pharmacological activities such as anticancer, chemopreventive, and cardioprotective…”
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High-density lipoprotein ameliorates palmitic acid-induced lipotoxicity and oxidative dysfunction in H9c2 cardiomyoblast cells via ROS suppression
Published in Nutrition & metabolism (28-05-2019)“…High levels circulating saturated fatty acids are associated with diabetes, obesity and hyperlipidemia. In heart, the accumulation of saturated fatty acids has…”
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HMGB1 promotes ERK-mediated mitochondrial Drp1 phosphorylation for chemoresistance through RAGE in colorectal cancer
Published in Cell death & disease (26-09-2018)“…Dysfunctional mitochondria have been shown to enhance cancer cell proliferation, reduce apoptosis, and increase chemoresistance. Chemoresistance develops in…”
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Clinical significance of programmed death 1 ligand-1 (CD274/PD-L1) and intra-tumoral CD8+ T-cell infiltration in stage II–III colorectal cancer
Published in Scientific reports (23-10-2018)“…Programmed cell death-1 (PDCD1/PD-1) and its ligand programmed cell death 1 ligand 1 (CD274/PD-L1) have been reported to suppress anti-tumor T cell-mediated…”
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ROS‐ and HIF1α‐dependent IGFBP3 upregulation blocks IGF1 survival signaling and thereby mediates high‐glucose‐induced cardiomyocyte apoptosis
Published in Journal of cellular physiology (01-08-2019)“…The prevalence of chronic hyperglycemia and its complications, imposing a critical burden on the worldwide economy and the global healthcare system, is a…”
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