Search Results - "Chies, J.A.B"

Tolerance versus immune response — MicroRNAs as important elements in the regulation of the HLA-G gene expression by Veit, T.D, Chies, J.A.B

“…Abstract HLA-G is a class Ib HLA which has gained much attention due to its multiple functions on the immune system. HLA-G exerts several immunomodulatory…”
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Matrix metalloproteinase gene polymorphisms and susceptibility to systemic sclerosis by Rech, T F, Moraes, S B C, Bredemeier, M, de Paoli, J, Brenol, J C T, Xavier, R M, Chies, J A B, Simon, D

“…The major pathological hallmark of the systemic sclerosis (SSc) is skin and internal organ fibrosis, which results from normal tissue architecture alterations…”
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HO-1 polymorphism as a genetic determinant behind the malaria resistance afforded by haemolytic disorders by Garcia-Santos, D, Chies, J.A.B

“…Summary Malaria affects thousands of people around the world representing a critical issue regarding health policies in tropical countries. Similarly, also…”
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The use of stem cells for the treatment of autoimmune diseases by Rosa, S B, Voltarelli, J C, Chies, J A B, Pranke, P

“…Autoimmune diseases constitute a heterogeneous group of conditions commonly treated with anti-inflammatory, immunosuppressant and immunomodulating drugs, with…”
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ABCB1 C1236T, G2677T/A and C3435T polymorphisms in systemic lupus erythematosus patients by Gonzalez, T P, Mucenic, T, Brenol, J C T, Xavier, R M, Schiengold, M, Chies, J A B

“…P-glycoprotein (Pgp), the ABCB1 gene product, acts as an efflux pump that transports a large variety of substrates and is a mechanism of cell protection…”
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High frequency of the CCR5delta32 variant among individuals from an admixed Brazilian population with sickle cell anemia by Chies, J A B, Hutz, M H

“…Homozygous sickle cell disease (SCD) has a wide spectrum of clinical manifestations. In Brazil, the main cause of death of individuals with SCD is recurrent…”
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Immunological success of pregnancy: Effector cellular functions and maternal HLA-G polymorphism by Vianna, P, Dalmáz, C.A, Tedoldi, C, Roisenberg, I, Chies, J.A.B

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Frequency of CCR5delta32 in Brazilian populations by Vargas, A E, Marrero, A R, Salzano, F M, Bortolini, M C, Chies, J A B

“…A sample of 103 randomly chosen healthy individuals from Alegrete, RS, Brazil, was tested for the CCR5delta32 allele, which is known to influence…”
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Letter To the Editor: On the haplotypic frequencies of the MBL2 gene among human populations by Chies, J.A.B.

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Impact of aerobic water running training on peripheral immune-endocrine markers of overweight-obese women by Colato, A., Fraga, L., Dorneles, G., Vianna, P., Chies, J.A.B., Peres, A.

“…The purpose of this study was to evaluate the effect of water running training on immune-endocrine parameters evaluated in peripheral blood of overweight-obese…”
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Killer cell immunoglobulin-like receptor (KIR) genes in systemic sclerosis by Salim, P.H, Jobim, M, Bredemeier, M, Chies, J.A.B, Schlottfeldt, J, Brenol, J.C.T, Jobim, L.F, Xavier, R.M

“…A previous study has suggested that the combination KIR2DS2⁺/KIR2DL2⁻ was related to increased risk for systemic sclerosis (SSc), while others have failed to…”
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Immunodominant viral peptides as determinants of cross-reactivity in the immune system – Can we develop wide spectrum viral vaccines? by Vieira, G.F., Chies, J.A.B.

“…When we look back to Edward Jenner vaccination of a young man in 1796, we cannot help thinking that he was both lucky and crazy. Crazy because he decided to…”
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Sickle cell disease: a chronic inflammatory condition by Chies, J.A.B., Nardi, N.B.

“…Homozygous sickle cell disease (SCD) has a wide spectrum of clinical manifestations which varies from an almost asymptomatic condition to severe illness,…”
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Copper ions dynamically regulate β3 integrin subunit expression in Ishikawa cells by Savaris, R., Chies, J.A.B.

“…Copper intrauterine device (IUD) users have a reduced expression of β3 integrin subunit during the implantation window. This integrin has been found to be a…”
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Induction of fetal haemoglobin expression in erythroid cells – A model based on iron availability signalling by Delgado-Cañedo, A., Chies, J.A.B., Nardi, N.B.

“…The K562 cell line has erythroid origin and is used for the study of fetal haemoglobin (HbF) production after treatment with several drugs, such as…”
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Immunosuppressive therapy for kidney transplant prevents vaso-occlusive crisis in a haemoglobin SC disease patient by Chies, J.A.B., Dresch, C., Cruz, M.S., da Silva, G., Barros, E., Bittar, C., Friedrisch, J., Silla, L.M.R.

“…Although the molecular basis of sickle cell disease (SCD) is well established, the wide variability in clinical manifestations still puzzles haematologists and…”
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