Search Results - "Chieh, J. J."
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Macro‐ and micro‐scale culture environment differentially regulate the effects of crowding on macrophage function
Published in Biotechnology and bioengineering (01-01-2024)“…Macrophages hold vital roles in immune defense, wound healing, and tissue homeostasis, and have the exquisite ability to sense and respond to dynamically…”
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Lower Airway Dysbiosis Affects Lung Cancer Progression
Published in Cancer discovery (01-02-2021)“…In lung cancer, enrichment of the lower airway microbiota with oral commensals commonly occurs, and models support that some of these bacteria can trigger host…”
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3
A Panel of Novel Detection and Prognostic Methylated DNA Markers in Primary Non-Small Cell Lung Cancer and Serum DNA
Published in Clinical cancer research (15-11-2017)“…To establish a novel panel of cancer-specific methylated genes for cancer detection and prognostic stratification of early-stage non-small cell lung cancer…”
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4
Airway Microbiota Is Associated with Upregulation of the PI3K Pathway in Lung Cancer
Published in American journal of respiratory and critical care medicine (01-11-2018)“…In lung cancer, upregulation of the PI3K (phosphoinositide 3-kinase) pathway is an early event that contributes to cell proliferation, survival, and tissue…”
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5
Diet-induced adaptive thermogenesis requires neuropeptide FF receptor-2 signalling
Published in Nature communications (09-11-2018)“…Excess caloric intake results in increased fat accumulation and an increase in energy expenditure via diet-induced adaptive thermogenesis; however, the…”
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6
Exclusive use of ultrasound for locating optimal LVA sites—A descriptive data analysis
Published in Journal of surgical oncology (01-01-2020)“…Background The current standard to locate lymphatic vessels for lymphovenous anastomosis (LVA) is the use of indocyanine green (ICG)‐lymphangiography. Due to…”
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7
Germ-free C57BL/6J mice are resistant to high-fat-diet-induced insulin resistance and have altered cholesterol metabolism
Published in The FASEB journal (01-12-2010)“…Recent studies showed that germ-free (GF) mice are resistant to obesity when consuming a high-fat, high-carbohydrate Western diet. However, it remains unclear…”
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8
Controversies and challenges in lung cancer screening
Published in Seminars in oncology (01-06-2022)“…Two large randomized controlled trials have shown mortality benefit from lung cancer screening (LCS) in high-risk groups. Updated guidelines by the United…”
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Episodic Aspiration with Oral Commensals Induces a MyD88-dependent, Pulmonary T-Helper Cell Type 17 Response that Mitigates Susceptibility to Streptococcus pneumoniae
Published in American journal of respiratory and critical care medicine (01-05-2021)“…Cross-sectional human data suggest that enrichment of oral anaerobic bacteria in the lung is associated with an increased T-helper cell type 17 (Th17)…”
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10
Risk of new-onset diabetes mellitus in primary aldosteronism: a population study over 5 years
Published in Journal of hypertension (01-08-2017)“…OBJECTIVE:Abnormal glucose metabolism due to insulin resistance has been linked to aldosterone overproduction. However, the long-term incidence of new-onset…”
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11
Epigenetically regulated PAX6 drives cancer cells toward a stem-like state via GLI-SOX2 signaling axis in lung adenocarcinoma
Published in Oncogene (01-11-2018)“…It remains unclear whether PAX6 acts as a crucial transcription factor for lung cancer stem cell (CSC) traits. We demonstrate that PAX6 acts as an oncogene…”
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12
Laparoendoscopic single‐site (LESS) vs laparoscopic living‐donor nephrectomy: a systematic review and meta‐analysis
Published in BJU international (01-02-2015)“…The aim of this study was to provide a systematic review and meta‐analysis of reports comparing laparoendoscopic single‐site (LESS) living‐donor nephrectomy…”
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13
Network biology analysis of P23H rhodopsin interactome identifies protein and mRNA quality control mechanisms
Published in Scientific reports (18-10-2022)“…Rhodopsin is essential for phototransduction, and many rhodopsin mutations cause heritable retinal degenerations. The P23H rhodopsin variant generates a…”
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14
Could the Sputum Microbiota Be a Biomarker That Predicts Mortality after Acute Exacerbations of Chronic Obstructive Pulmonary Disease?
Published in American journal of respiratory and critical care medicine (15-05-2019)“…In this issue of the Journal, Leitao Filho and colleagues (pp. 1205-1213) used sputum samples obtained at the time of hospital admission for AECOPD in 102…”
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15
Enrichment of the lung microbiome with oral taxa is associated with lung inflammation of a Th17 phenotype
Published in Nature microbiology (04-04-2016)“…Microaspiration is a common phenomenon in healthy subjects, but its frequency is increased in chronic inflammatory airway diseases, and its role in…”
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The lung microbiome, peripheral gene expression, and recurrence-free survival after resection of stage II non-small cell lung cancer
Published in Genome medicine (27-10-2022)“…Cancer recurrence after tumor resection in early-stage non-small cell lung cancer (NSCLC) is common, yet difficult to predict. The lung microbiota and systemic…”
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Bioelectronic silicon nanowire devices using functional membrane proteins
Published in Proceedings of the National Academy of Sciences - PNAS (18-08-2009)“…Modern means of communication rely on electric fields and currents to carry the flow of information. In contrast, biological systems follow a different…”
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Is the Gut Microbiota a New Factor Contributing to Obesity and Its Metabolic Disorders?
Published in Journal of Obesity (01-01-2012)“…The gut microbiota refers to the trillions of microorganisms residing in the intestine and is integral in multiple physiological processes of the host. Recent…”
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Derivation of 3D Coseismic Displacement Field from Integrated Azimuth and LOS Displacements for the 2018 Hualien Earthquake
Published in Remote sensing (Basel, Switzerland) (01-04-2024)“…A 3D surface deformation field for an earthquake can aid in understanding fault behaviors and earthquake mechanisms. However, SAR-based 3D surface deformation…”
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Inflammation in the tumor-adjacent lung as a predictor of clinical outcome in lung adenocarcinoma
Published in Nature communications (08-11-2023)“…Approximately 30% of early-stage lung adenocarcinoma patients present with disease progression after successful surgical resection. Despite efforts of mapping…”
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