Search Results - "Chidara, Sridhar"
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An efficient Mn-catalyzed reductive carbonylation of aryl iodides to aryl aldehydes and their benzimidazole and benzoxazoles
Published in Synthetic communications (03-08-2022)“…The present study envisaged the development of an efficient protocol of Mn-catalyzed reductive carbonylation of aryl iodides to aryl aldehydes and their…”
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2
Stereoselective total synthesis of Aspergillide D
Published in Natural product research (18-10-2023)“…The total synthesis of the 16-membered Polyhydroxylated macrolide, Aspergillide D has been accomplished utilizing the Grignard reaction, Sharpless asymmetric…”
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3
Design, Synthesis, Molecular Docking Study and Biological Evaluation of Novel γ-Carboline Derivatives of Latrepirdine (Dimebon) as Potent Anticancer Agents
Published in Molecules (Basel, Switzerland) (24-06-2023)“…A series of novel γ-Carboline derivatives were designed and synthesized using the Suzuki coupling reaction to identify the leads for the activity against…”
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4
Rational design, synthesis and biological evaluation 1,2,3-triazole aryl attached (4,6-dimethoxy-1,3,5-triazin-2-yl)thiazole derivatives as anticancer agents
Published in Results in Chemistry (01-10-2024)“…[Display omitted] A new library of 1,2,3-triazole aryl-attached (4,6-dimethoxy-1,3,5-triazin-2-yl) thiazoles (11a–j) has been designed and synthesized and its…”
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5
Discovery of tetrahydro γ-carboline based novel glucose uptake agent for the treatment of diabetes and Alzheimer’s diseases
Published in Results in Chemistry (01-10-2024)“…[Display omitted] •Tetrahydro γ-Carbolines show potential in treating both T2DM and Alzheimer’s disease.•Compound 11a enhances glucose uptake in adipocytes,…”
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6
Nickel catalysed carbonylative Sonogashira reaction for the synthesis of diarylalkynones and 2-substituted flavones
Published in Tetrahedron letters (22-08-2018)“…[Display omitted] •Ligand free Nickel Catalyzed Carbonylative Sonogashira was developed.•Various α, β-alkynyl ketones and flavones synthesized.•Economically…”
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One-pot synthesis of trisubstituted 2-pyrones and polysubstituted phenols through Zn catalyzed cascade of ynone/condensation/elimination reactions
Published in Synthetic communications (18-10-2023)“…An efficient multicomponent method is described for the synthesis of a variety of trisubstituted 2-pyrones and polysubstituted phenols based on the…”
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8
Steroselective total synthesis of Neocosmosin B
Published in Tetrahedron (23-04-2022)“…[Display omitted]…”
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9
An efficient synthesis of 3-fluoro chromones from the tandem cyclization of enaminones by using N-Fluoro benzenesulfonimide
Published in Synthetic communications (17-09-2023)“…An efficient method of synthesizing the various 3-Fluorochromones from enamino ketones by using N-Fluoro benzenesulfonimide (NFSI) is described. The key step…”
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10
Ligand-free Zn-catalyzed double carbonylation of aryl iodides with secondary amines: A simple and efficient approach to access α-ketoamides
Published in Synthetic communications (17-01-2022)“…Herein, we report a Zinc catalyzed double carbonylation of aryl iodides with secondary amines under CO pressure for the synthesis of α-ketoamides in good to…”
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11
Total synthesis of (3R, 4S)-4-hydroxylasiodiplodin
Published in Natural product research (18-04-2023)“…An efficient stereoselective total synthesis of (3R, 4S)-4-hydroxylasiodiplodin has been accomplished starting from known starting materials. The key steps…”
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12
Greener route for the synthesis of chromone using Amberlyst®15 via enaminones
Published in ARKIVOC free online journal of organic chemistry (01-11-2022)Get full text
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13
Synthesis of Substituted Benzimidazoles and Benzoxazoles by Iron‐catalysed Reductive Carbonylation of Aryl Iodides
Published in ChemistrySelect (Weinheim) (18-07-2024)“…This work describes a novel iron‐catalysed approach for the synthesis of aryl‐substituted benzimidazoles and benzoxazoles. The methodology employs reductive…”
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14
Highly efficient approach to the total synthesis of flavoxate hydrochloride
Published in Chemical Data Collections (01-06-2021)“…An efficient and short approach to the total synthesis of flavoxate hydrochloride, a muscle relaxant in urinary bladder, is reported. The synthesis of…”
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15
Synthesis and Evaluation of Novel Quinazolinone Thioether Linked 5-Aryl-1,2,4-Triazoles for Anticancer and Antimicrobial Activity
Published in Polycyclic aromatic compounds (02-07-2024)“…A series of 5-Aryl-1,2,4-triazole derivatives linked by Quinazolin-4-one thioether were designed and synthesized through condensation reactions. The structure…”
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16
An Efficient Base-Free N-Arylation of Imidazoles and Amines with Arylboronic Acids Using Copper-Exchanged Fluorapatite
Published in Journal of organic chemistry (08-12-2006)“…N-Arylation of imidazoles and amines with arylboronic acids was accomplished with copper-exchanged fluorapatite (CuFAP) in methanol at room temperature. The…”
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17
Total synthesis of (3R,5R) and (3R,5S)-sonnerlactones
Published in Tetrahedron letters (20-04-2016)“…In this Letter, an enantioselective synthesis of (3R,5R)-sonnerlactone and (3R,5S)-sonnerlactone have been described. Stereochemistry at C-5 position was fixed…”
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18
Design and Evolution of Copper Apatite Catalysts for N-Arylation of Heterocycles with Chloro- and Fluoroarenes
Published in Journal of the American Chemical Society (20-07-2005)“…We report the preparation of recyclable heterogeneous catalysts, copper-exchanged fluorapatite, and copper-exchanged tert-butoxyapatite by incorporating basic…”
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19
Synthesis of indolo[2,3-a]quinolizine and hexahydro-1H-indolizino[8,7-b]indole derivatives by cascade condensation, cyclization, and Pictet–Spengler reaction: an application to the synthesis of (±)-harmicine
Published in Tetrahedron letters (12-09-2012)“…Synthesis of indole alkaloid related compounds using Schiff base formation, intramolecular cyclization (or N-alkylation), and Pictet–Spengler reaction as a…”
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20
Microwave‐Assisted Reductive Amination of 2‐Carboxybenzaldehydes with Amines for the Synthesis of N‐Substituted Isoindolin‐1‐one
Published in ChemistrySelect (Weinheim) (06-09-2022)“…Microwave‐assisted, transition metal free methodology for the synthesis of N‐substituted isoindolin‐1‐one from 2‐carboxybenzaldehydes with various amines by…”
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