Search Results - "Chidambaram, Anusha"
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Copper oxide nanoparticles induce anticancer activity in A549 lung cancer cells by inhibition of histone deacetylase
Published in Biotechnology letters (01-02-2018)“…Objectives Copper oxide nanoparticles (CuO NPs) promoting anticancer activity may be due to the regulation of various classes of histone deacetylases (HDACs)…”
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Avicennia marina engineered nanoparticles induce apoptosis in adenocarcinoma lung cancer cell line through p53 mediated signaling pathways
Published in Process biochemistry (1991) (01-07-2020)“…[Display omitted] •Synthesis of bioengineered AgNPs using Leaf extract of Avicennia marina.•The prepared AgNPs showed spherical crystalline and monodispersed…”
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Plant Isoquinoline Alkaloid Berberine Exhibits Chromatin Remodeling by Modulation of Histone Deacetylase To Induce Growth Arrest and Apoptosis in the A549 Cell Line
Published in Journal of agricultural and food chemistry (21-12-2016)“…Histone deacetylases (HDACs) are a group of epigenetic enzymes that control gene expression through their repressive influence on histone deacetylation…”
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Blocking NF-κB sensitizes non-small cell lung cancer cells to histone deacetylase inhibitor induced extrinsic apoptosis through generation of reactive oxygen species
Published in Biomedicine & pharmacotherapy (01-02-2015)“…Abstract NF-κB signalling is one of the main cell survival pathways that attenuate the anticancer efficacy of therapeutic drugs. Previous studies demonstrated…”
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Facile synthesis of Curcuma longa tuber powder engineered metal nanoparticles for bioimaging applications
Published in Journal of molecular structure (05-02-2017)“…Nanomaterials based fluorescent agents are rapidly becoming significant and promising transformative tools for improving medical diagnostics for extensive…”
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Fourier transform-infrared spectroscopy as a diagnostic tool for mosquito coil smoke inhalation toxicity in Swiss Albino mice
Published in Journal of molecular structure (05-12-2017)“…The goal of this study is to establish Fourier transform-infrared (FTIR) spectroscopy as a diagnostic tool for allethrin-based mosquito coil smoke inhalation…”
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Design, synthesis, and characterization of α, β‐unsaturated carboxylic acid, and its urea based derivatives that explores novel epigenetic modulators in human non‐small cell lung cancer A549 cell line
Published in Journal of cellular physiology (01-07-2018)“…Histone deacetylase inhibitors (HDACi) are a small molecule chemotherapeutics that target the chromatin remodeling through the regulation of histone and…”
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Synthesis, characterization, and evaluation of Cd[L-proline]2, a novel histone deacetylase inhibitor that induces epigenetic modification of histone deacetylase isoforms in A549 cells
Published in Investigational new drugs (01-12-2017)“…Summary Histone deacetylases (HDACs) play an important role in the epigenetic regulation of gene expression through their effects on the compact chromatin…”
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m -nitrobenzaldehyde thiosemicarbazone induces ROS mediated apoptosis via p53 dependent intrinsic pathway in non-small cell lung cancer A549 cell line
Published in Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy (2016)“…Abstract Numerous cancer researchers focus on to develop novel drugs for chemotherapy. In this way, synthesized m- nitro benzaldehyde thiosemicarbazone (NBTSC)…”
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