Search Results - "Chick, Robert C."

Correlation of tumor microenvironment from biopsy and resection specimens in untreated colorectal cancer patients: a surprising lack of agreement by Kemp Bohan, Phillip M., Chick, Robert C., Hickerson, Annelies T., Messersmith, Lynn M., Williams, Grant M., Cindass, Jessica L., Lombardo, Jamie, Collins, Ryan, Brady, Robert O., Hale, Diane F., Peoples, George E., Vreeland, Timothy J., Clifton, Guy T.

“…Background Colorectal cancer (CRC) tumor microenvironment (TME) characteristics, such as tumor infiltrating lymphocyte (TIL) densities and PD-L1 status, are…”
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Meeting the New Commission on Cancer Operative Standards: Where Do We Stand Now? by Carpenter, Elizabeth L, Adams, Alexandra M, McCarthy, Patrick M, Chick, Robert C, Spitzer, Holly V, Nelson, Daniel W, Clifton, Guy T, Bowen, Donnell K, Krell, Robert W, Vreeland, Timothy J

“…ABSTRACT Introduction The 2020 Commission on Cancer accreditation standards 5.7 and 5.8 address total mesorectal excision for rectal cancer and lymph node…”
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Tumor lysate particle only vaccine (TLPO) vs. Tumor lysate particle-loaded, dendritic cell vaccine (TLPLDC) to prevent recurrence in resected stage III/IV melanoma patients: Results of a phase I/IIa trial by Van Decar, Spencer G., Carpenter, Elizabeth L., Adams, Alexandra M., Chick, Robert C., Clifton, Guy T., Stojadinovic, Alex, Vreeland, Timothy J., Valdera, Franklin A., Tiwari, Ankur, O'Shea, Anne E., McCarthy, Patrick M., Hale, Diane F., Bohan, Phillip M Kemp, Hickerson, Annelies T., Cindass, Jessica L., Hyngstrom, John, Berger, Adam C., Jakub, James W., Sussman, Jeffrey J., Shaheen, Montaser, Yu, Xianzhong, Wagner, Thomas, Faries, Mark B., Peoples, George E.

“…•Promoting a targeted host immune response via autologous tumor neoantigen vaccination is an evolving field.•Adjuvant autologous tumor vaccines (TLPO and…”
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Multi‐institutional, prospective, randomized, double‐blind, placebo‐controlled phase IIb trial of the tumor lysate, particle‐loaded, dendritic cell (TLPLDC) vaccine to prevent recurrence in high‐risk melanoma patients: A subgroup analysis by Chick, Robert C., Faries, Mark B., Hale, Diane F., Kemp Bohan, Phillip M, Hickerson, Annelies T., Vreeland, Timothy J., Myers, John W., Cindass, Jessica L., Brown, Tommy A., Hyngstrom, John, Berger, Adam C., Jakub, James W., Sussman, Jeffrey J., Shaheen, Montaser, Clifton, Guy T., Park, Hyohyun, Sloan, Amanda J., Wagner, Thomas, Peoples, George E.

“…Background Checkpoint inhibitors (CPI) in combination with cell‐based vaccines may produce synergistic antitumor immunity. The primary analysis of the…”
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Secondary Overtriage in Patients with Complicated Mild Traumatic Brain Injury: An Observational Study and Socioeconomic Analysis of 1447 Hospitalizations by Dengler, Bradley A, Plaza-Wüthrich, Sonia, Chick, Robert C, Muir, Mark T, Bartanusz, Viktor

“…Abstract BACKGROUND Secondary overtriage is a problematic phenomenon because it creates unnecessary expense and potentially results in the mismanagement of…”
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Safety and efficacy of low-titer O whole blood resuscitation in a civilian level I trauma center by Kemp Bohan, Phillip M., McCarthy, Patrick M., Wall, Morgan E., Adams, Alexandra M., Chick, Robert C., Forcum, Jason E., Radowsky, Jason S., How, Remealle A., Sams, Valerie G.

“…BACKGROUND Military experience has shown low-titer O whole blood (LTOWB) to be safe and beneficial in the resuscitation of hemorrhaging trauma patients…”
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Adjuvant Chemotherapy in Resectable Gallbladder Cancer is Underutilized Despite Benefits in Node-Positive Patients by Kemp Bohan, Phillip M., Kirby, Derek T., Chick, Robert C., Bader, Julia O., Clifton, G. Travis, Vreeland, Timothy J., Nelson, Daniel W.

“…Background Adjuvant chemotherapy (AC) is recommended following surgical resection of gallbladder cancer regardless of stage. However, stage-specific benefits…”
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Downstaging of Pancreatic Adenocarcinoma With Either Neoadjuvant Chemotherapy or Chemoradiotherapy Improves Survival by O’Shea, Anne E., Bohan, Phillip M. Kemp, Carpenter, Elizabeth L., McCarthy, Patrick M., Adams, Alexandra M., Chick, Robert C., Bader, Julia O., Krell, Robert W., Peoples, George E., Clifton, Guy T., Nelson, Daniel W., Vreeland, Timothy J.

“…Background Neoadjuvant chemotherapy (NAC) or chemoradiation (NAC+XRT) is incorporated into the treatment of localized pancreatic adenocarcinoma (PDAC), often…”
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A Phase IIb Randomized Controlled Trial of the TLPLDC Vaccine as Adjuvant Therapy After Surgical Resection of Stage III/IV Melanoma: A Primary Analysis by Vreeland, Timothy J., Clifton, Guy T., Hale, Diane F., Chick, Robert C., Hickerson, Annelies T., Cindass, Jessica L., Adams, Alexandra M., Bohan, Phillip M. Kemp, Andtbacka, Robert H. I., Berger, Adam C., Jakub, James W., Sussman, Jeffrey J., Terando, Alicia M., Wagner, Thomas, Peoples, George E., Faries, Mark B.

“…Background Melanoma therapy has changed dramatically over the last decade with improvements in immunotherapy, yet many patients do not respond to current…”
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Chemoprevention in familial adenomatous polyposis: past, present and future by Kemp Bohan, Phillip M., Mankaney, Gautam, Vreeland, Timothy J., Chick, Robert C., Hale, Diane F., Cindass, Jessica L., Hickerson, Annelies T., Ensley, Daniel C., Sohn, Vance, Clifton, G. Travis, Peoples, George E., Burke, Carol A.

“…Familial adenomatous polyposis (FAP) is a hereditary colorectal cancer syndrome characterized by colorectal adenomas and a near 100% lifetime risk of…”
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Maximizing Benefit of Virtual Learning: Lessons From the Coronavirus Disease 2019 Pandemic by Carpenter, Elizabeth L., Adams, Alexandra M., Chick, Robert C., Stull, Mamie C., Hale, Diane F., Propper, Brandon W., Clifton, Guy T., Vreeland, Timothy J.

“…The coronavirus disease 2019 pandemic has profoundly impacted surgical education. We assessed resident perceptions of our virtual academic program, which…”
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Predictors and benefits of multiagent chemotherapy for pancreatic adenocarcinoma: Timing matters by Valdera, Franklin A., O'Shea, Anne E., Smolinsky, Todd R., Carpenter, Elizabeth L., Adams, Alexandra A., McCarthy, Patrick M., Tiwari, Ankur, Chick, Robert C., Kemp‐Bohan, Phillip M., Van Decar, Spencer, Thomas, Katryna K., Bader, Julia O., Peoples, George E., Clifton, Guy T., Stojadinovic, Alex, Nelson, Daniel W., Vreeland, Timothy J.

“…Introduction Adjuvant (A) multiagent chemotherapy (MC) is the standard of care for patients with pancreatic adenocarcinoma (PDAC). Tolerating MC following a…”
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An Educational Intervention Reduces Opioids Prescribed Following General Surgery Procedures by Kemp Bohan, Phillip M., Chick, Robert C., Wall, Morgan E., Hale, Diane F., Tzeng, Ching-Wei D., Peoples, George E., Vreeland, Timothy J., Clifton, G. Travis

“…Variability exists in opioid prescribing practices among surgeons, frequently resulting in the prescription of excessive opioids. This study evaluated the…”
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Rates, Predictors, and Outcomes of Portal Lymphadenectomy for Resectable Gallbladder Cancer by Kemp Bohan, Phillip M., O’Shea, Anne E., Ellis, Oriana V., Chick, Robert C., Clem, Alex M., Kirby, Derek T., Bader, Julia O., Newhook, Timothy E., Clifton, G. Travis, Tzeng, Ching-Wei D., Nelson, Daniel W., Vreeland, Timothy J.

“…Introduction Lymphadenectomy (LND) is recommended following surgical resection of ≥ T1b gallbladder cancer (GBC). However, frequency and stage-specific…”
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Divergent clinical outcomes in a phase 2B trial of the TLPLDC vaccine in preventing melanoma recurrence and the impact of dendritic cell collection methodology: a randomized clinical trial by Adams, Alexandra M., Carpenter, Elizabeth L., Clifton, Guy T., Vreeland, Timothy J., Chick, Robert C., O’Shea, Anne E., McCarthy, Patrick M., Kemp Bohan, Phillip M., Hickerson, Annelies T., Valdera, Franklin A., Tiwari, Ankur, Hale, Diane F., Hyngstrom, John R., Berger, Adam C., Jakub, James W., Sussman, Jeffrey J., Shaheen, Montaser F., Yu, Xianzhong, Wagner, Thomas E., Faries, Mark B., Peoples, George E.

“…Background A randomized, double-blind, placebo-controlled phase 2b trial of the tumor lysate, particle-loaded, dendritic cell (TLPLDC) vaccine was conducted in…”
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Phase I Trial of Encapsulated Rapamycin in Patients with Prostate Cancer Under Active Surveillance to Prevent Progression by Kemp Bohan, Phillip M, Chick, Robert C, O'Shea, Anne E, Vreeland, Timothy J, Hickerson, Annelies T, Cindass, Jessica L, Ensley, Daniel C, Hale, Diane, Clifton, Guy T, Sohn, Vance Y, Thompson, Jr, Ian M, Peoples, George E, Liss, Michael A

“…No approved medical therapies prevent progression of low-grade prostate cancer. Rapamycin inhibits cell proliferation and augments immune responses, producing…”
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Safety and efficacy of autologous tumor lysate particle-loaded dendritic cell vaccination in combination with systemic therapies in patients with recurrent and metastatic melanoma by Adams, Alexandra M., Chick, Robert C., Vreeland, Timothy J., Clifton, Guy T., Hale, Diane F., McCarthy, Patrick M., O’Shea, Anne E., Bohan, Phillip M. Kemp, Hickerson, Annelies T., Park, Hyohyun, Sloan, Amanda JoEllen, Hyngstrom, John, Berger, Adam C., Jakub, James W., Sussman, Jeffrey J., Shaheen, Montaser, Wagner, Thomas, Faries, Mark B., Peoples, George E.

“…Immunotherapy has revolutionized the treatment of melanoma, yet survival remains poor for patients with metastatic disease. The autologous tumor lysate,…”
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Lymph node sampling in resectable hepatocellular carcinoma: national practice patterns and predictors of positive lymph nodes by Kemp Bohan, Phillip M., O'Shea, Anne E., Lee, Andrew J., Chick, Robert C., Newhook, Timothy E., Tran Cao, Hop S., Allen, Casey J., Nelson, Daniel W., Clifton, G. Travis, Vauthey, Jean-Nicolas, Tzeng, Ching-Wei D., Vreeland, Timothy J.

“…Routine lymphadenectomy (LND) for resectable hepatocellular carcinoma (HCC) remains controversial. We evaluated national LND trends to identify pre-operative…”
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Mo2027 PORTAL LYMPHADENECTOMY REDUCES RISK OF DEATH IN PATIENTS WITH RESECTABLE, NON-METASTATIC GALLBLADDER CANCER by Bohan, Phillip Kemp, Kirby, Derek, Chick, Robert C., Newhook, Timothy, Clifton, Guy T., Nelson, Daniel, Vreeland, Timothy J.

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An Autologous Tumor Lysate Dendritic Cell Vaccine Is Most Effective in Recurrent, Advanced-Stage Melanoma in a Randomized Controlled Trial by O'Shea, Anne, Chick, Robert C., Adams, Alexandra, McCarthy, Patrick, Bohan, Phillip Kemp, Vreeland, Timothy J., Clifton, Guy T., Peoples, George E.

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