Search Results - "Chicco, Adam J"

Role of cardiolipin alterations in mitochondrial dysfunction and disease by Chicco, Adam J, Sparagna, Genevieve C

“…Cardiolipin (CL) is a structurally unique dimeric phospholipid localized in the inner mitochondrial membrane where it is required for optimal mitochondrial…”
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Adiposity in mares induces insulin dysregulation and mitochondrial dysfunction which can be mitigated by nutritional intervention by Fresa, Kyle, Catandi, Giovana D., Whitcomb, Luke, Gonzalez-Castro, Raul A., Chicco, Adam J., Carnevale, Elaine M.

“…Obesity is a complex disease associated with augmented risk of metabolic disorder development and cellular dysfunction in various species. The goal of the…”
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Pro-inflammatory mediation of myoblast proliferation by Otis, Jeffrey S, Niccoli, Sarah, Hawdon, Nicole, Sarvas, Jessica L, Frye, Melinda A, Chicco, Adam J, Lees, Simon J

“…Skeletal muscle satellite cell function is largely dictated by the surrounding environment following injury. Immune cell infiltration dominates the…”
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Follicular metabolic alterations are associated with obesity in mares and can be mitigated by dietary supplementation by Catandi, Giovana D., Fresa, Kyle J., Cheng, Ming-Hao, Whitcomb, Luke A., Broeckling, Corey D., Chen, Thomas W., Chicco, Adam J., Carnevale, Elaine M.

“…Obesity is a growing concern in human and equine populations, predisposing to metabolic pathologies and reproductive disturbances. Cellular lipid accumulation…”
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Cathepsin K Knockout Alleviates Pressure Overload–Induced Cardiac Hypertrophy by Hua, Yinan, Xu, Xihui, Shi, Guo-Ping, Chicco, Adam J, Ren, Jun, Nair, Sreejayan

“…Evidence from human and animal studies has documented elevated levels of lysosomal cysteine protease cathepsin K in failing hearts. Here, we hypothesized that…”
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Alterations of biaxial viscoelastic properties of the right ventricle in pulmonary hypertension development in rest and acute stress conditions by Liu, Wenqiang, LeBar, Kristen, Roth, Kellan, Pang, Jassia, Ayers, Jessica, Chicco, Adam J, Puttlitz, Christian M, Wang, Zhijie

“…The right ventricle (RV) mechanical property is an important determinant of its function. However, compared to its elasticity, RV viscoelasticity is much less…”
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Loss of cardiac tetralinoleoyl cardiolipin in human and experimental heart failure by Sparagna, Genevieve C., Chicco, Adam J., Murphy, Robert C., Bristow, Michael R., Johnson, Christopher A., Rees, Meredith L., Maxey, Melissa L., McCune, Sylvia A., Moore, Russell L.

“…The mitochondrial phospholipid cardiolipin is required for optimal mitochondrial respiration. In this study, cardiolipin molecular species and cytochrome…”
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Study of Real-Time Spatial and Temporal Behavior of Bacterial Biofilms Using 2-D Impedance Spectroscopy by Begly, Caleb, Ackart, David, Mylius, Julian, Basaraba, Randall, Chicco, Adam J., Chen, Thomas W.

“…Objective: The purpose of this paper is to demonstrate the use of 2-D impedance spectroscopy to identify areas of biofilm growth on a CMOS biosensor…”
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Switching to a Standard Chow Diet at Weaning Improves the Effects of Maternal and Postnatal High-Fat and High-Sucrose Diet on Cardiometabolic Health in Adult Male Mouse Offspring by Chiñas Merlin, Andrea, Gonzalez, Kassandra, Mockler, Sarah, Perez, Yessenia, Jia, U-Ter Aondo, Chicco, Adam J., Ullevig, Sarah L., Chung, Eunhee

“…Cardiac mitochondrial dysfunction contributes to obesity-associated heart disease. Maternal and postnatal diet plays an important role in cardiac function, yet…”
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Cardiolipin biosynthesis and remodeling enzymes are altered during development of heart failure by Saini-Chohan, Harjot K., Holmes, Michael G., Chicco, Adam J., Taylor, William A., Moore, Russell L., McCune, Sylvia A., Hickson-Bick, Diane L., Hatch, Grant M., Sparagna, Genevieve C.

“…Cardiolipin (CL) is responsible for modulation of activities of various enzymes involved in oxidative phosphorylation. Although energy production decreases in…”
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Brain energy metabolism as an underlying basis of slow and fast cognitive phenotypes in honeybees by Tait, Catherine, Chicco, Adam J, Naug, Dhruba

“…In the context of slow-fast behavioral variation, fast individuals are hypothesized to be those who prioritize speed over accuracy while slow individuals are…”
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Dietary linoleate preserves cardiolipin and attenuates mitochondrial dysfunction in the failing rat heart by MULLIGAN, Christopher M, SPARAGNA, Genevieve C, HATCH, Grant M, MCCUNE, Sylvia A, MOORE, Russell L, CHICCO, Adam J, LE, Catherine H, DE MOOY, Anthony B, ROUTH, Melissa A, HOLMES, Michael G, HICKSON-BICK, Diane L, ZARINI, Simona, MURPHY, Robert C, XU, Fred Y

“…Cardiolipin (CL) is a tetra-acyl phospholipid that provides structural and functional support to several proteins in the inner mitochondrial membrane. The…”
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The role of calcium-independent phospholipase A2 in cardiolipin remodeling in the spontaneously hypertensive heart failure rat heart by Zachman, Derek K., Chicco, Adam J., McCune, Sylvia A., Murphy, Robert C., Moore, Russell L., Sparagna, Genevieve C.

“…Cardiolipin (CL) is an essential phospholipid component of the inner mitochondrial membrane. In the mammalian heart, the functional form of CL is…”
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Cardioprotection afforded by chronic exercise is mediated by the sarcolemmal, and not the mitochondrial, isoform of the KATP channel in the rat by Brown, David A., Chicco, Adam J., Jew, Korinne N., Johnson, Micah S., Lynch, Joshua M., Watson, Peter A., Moore, Russell L.

“…This study was conducted to examine the role of myocardial ATP-sensitive potassium (K ATP ) channels in exercise-induced protection from…”
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Low-intensity exercise training during doxorubicin treatment protects against cardiotoxicity by Chicco, Adam J, Hydock, David S, Schneider, Carole M, Hayward, Reid

“…School of Sport and Exercise Science and the Rocky Mountain Cancer Rehabilitation Institute, University of Northern Colorado, Greeley, Colorado Submitted 4…”
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Low-Intensity Exercise Training Delays Heart Failure and Improves Survival in Female Hypertensive Heart Failure Rats by Chicco, Adam J, McCune, Sylvia A, Emter, Craig A, Sparagna, Genevieve C, Rees, Meredith L, Bolden, David A, Marshall, Kurt D, Murphy, Robert C, Moore, Russell L

“…Exercise training improves functional capacity and quality of life in patients with heart failure. However, the long-term effects of exercise on mortality…”
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Cytonuclear integration and co-evolution by Sloan, Daniel B., Warren, Jessica M., Williams, Alissa M., Wu, Zhiqiang, Abdel-Ghany, Salah E., Chicco, Adam J., Havird, Justin C.

“…The partitioning of genetic material between the nucleus and cytoplasmic (mitochondrial and plastid) genomes within eukaryotic cells necessitates coordinated…”
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Role of the microtubule network in the passive anisotropic viscoelasticity of right ventricle with pulmonary hypertension progression by LeBar, Kristen, Liu, Wenqiang, Pang, Jassia, Chicco, Adam J., Wang, Zhijie

“…Cardiomyocytes are viscoelastic and contribute significantly to right ventricle (RV) mechanics. Microtubule, a cytoskeletal protein, has been shown to regulate…”
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Restoration of CREB function is linked to completion and stabilization of adaptive cardiac hypertrophy in response to exercise by Watson, Peter A, Reusch, Jane E B, McCune, Sylvia A, Leinwand, Leslie A, Luckey, Stephen W, Konhilas, John P, Brown, David A, Chicco, Adam J, Sparagna, Genevieve C, Long, Carlin S, Moore, Russell L

“…Potential regulation of two factors linked to physiological outcomes with left ventricular (LV) hypertrophy, resistance to apoptosis, and matching of metabolic…”
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Role of Microtubule Network in the Passive Anisotropic Viscoelasticity of Healthy Right Ventricle by LeBar, Kristen, Liu, Wenqiang, Chicco, Adam J, Wang, Zhijie

“…Cardiomyocytes are viscoelastic and key determinants of right ventricle (RV) mechanics. Intracellularly, microtubules are found to impact the viscoelasticity…”
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