Search Results - "Chibueze Agwu"
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MeCP2 represses the activity of topoisomerase IIβ in long neuronal genes
Published in Cell reports (Cambridge) (26-12-2023)“…A unique signature of neurons is the high expression of the longest genes in the genome. These genes have essential neuronal functions, and disruption of their…”
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Exploring the feasibility of pupillometry training and perceptions of potential use for intracranial pressure monitoring in Uganda: A mixed methods study
Published in PloS one (15-05-2024)“…Traumatic brain injury (TBI) accounts for the majority of Uganda's neurosurgical disease burden; however, invasive intracranial pressure (ICP) monitoring is…”
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Transcriptional analyses of adult and pediatric adamantinomatous craniopharyngioma reveals similar expression signatures regarding potential therapeutic targets
Published in Acta neuropathologica communications (13-05-2020)“…Adamantinomatous craniopharyngioma (ACP) is a biologically benign but clinically aggressive lesion that has a significant impact on quality of life. The…”
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872 Natural History of Conservatively Managed Patients With Chiari Malformation Type I and Syringomyelia
Published in Neurosurgery (01-04-2024)“…INTRODUCTION: Chiari malformation type 1 (CM1) describes caudal ectopia of the cerebellar tonsils. Though often asymptomatic earlier in life and found…”
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Cerebrospinal Fluid Diversion from the Cisterna Magna in Patients with Idiopathic Intracranial Hypertension and Slit Ventricles: Long-Term Effectiveness, Revision Rates, and Clinical Outcomes
Published in World neurosurgery (01-06-2024)“…Idiopathic intracranial hypertension (IIH) is a cerebrospinal fluid (CSF) disorder defect that is frequently treated with CSF shunts. Shunts utilizing the…”
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The Bias of Medicine in Sickle Cell Disease
Published in Journal of general internal medicine : JGIM (01-11-2023)“…Sickle cell disease (SCD) is the most common monogenetic condition in the United States (US) and one that has been subjected to a history of negative bias…”
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Understanding Hydroxyurea Utilization in Sickle Cell Disease: Exploring Patient and Provider Attitudes and Beliefs
Published in Blood (15-11-2022)Get full text
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A Mixed-Methods Assessment of the Feasibility of Conducting Neurosurgical Clinical Research in Uganda
Published in World neurosurgery (01-03-2024)“…Clinical research is necessary to evaluate neurosurgical interventions, yet clinical trials are conducted less frequently in low- and middle-income countries…”
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RARE-08. CYST FLUID CYTOKINES MAY PROMOTE EPITHELIAL-TO-MESENCHYMAL TRANSITION IN PEDIATRIC ADAMANTINOMATOUS CRANIOPHARYNGIOMA
Published in Neuro-oncology (Charlottesville, Va.) (04-12-2020)“…Abstract BACKGROUND Despite poor clinical outcomes, no targeted therapies have been established for the treatment of Adamantinomatous Craniopharyngioma (ACP)…”
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Exploring the feasibility of pupillometry training and perceptions of potential use for intracranial pressure monitoring in Uganda: A mixed methods study
Published in PloS one (01-01-2024)Get full text
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