Search Results - "Chiba, Mitsuru"
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Exosomes released from pancreatic cancer cells enhance angiogenic activities via dynamin-dependent endocytosis in endothelial cells in vitro
Published in Scientific reports (10-08-2018)“…Pancreatic cancer has the lowest 5 year survival rate among all cancers. Several extracellular factors are involved in the development and metastasis of…”
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2
Nationwide epidemiological survey of autoimmune pancreatitis in Japan in 2016
Published in Journal of gastroenterology (01-04-2020)“…Background To further clarify the clinico-epidemiological features of autoimmune pancreatitis (AIP) in Japan, we conducted the fourth nationwide…”
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A Preoperative Diagnosis of Advanced Cystic Duct Carcinoma Using SpyGlass DS Cholangioscopy: A Report of Two Cases
Published in Internal Medicine (01-06-2023)“…Primary cystic duct carcinoma is a rare tumor. The curative treatment of cystic duct carcinoma is complete surgical resection, for which the evaluation of…”
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4
Grade 3 Pancreatic Neuroendocrine Tumor Refractory to Chemotherapy Successfully Treated with Peptide Receptor Radionuclide Therapy Leading to Conversion Surgery
Published in Internal Medicine (2024)“…A 59-year-old woman was diagnosed with a pancreatic neuroendocrine tumor (P-NET; Grade 3, Ki67: 25%) with multiple liver and lymph node metastases and started…”
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5
Effects of voluntary and forced exercises on motor function recovery in intracerebral hemorrhage rats
Published in Neuroreport (27-01-2020)“…Motor paralysis is a severe consequence of intracerebral hemorrhage (ICH) that reduces patient quality of life. Rehabilitation is beneficial for stroke…”
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Extremely Late Recurrence of Ovarian Carcinoma Diagnosed by an Endoscopic Ultrasound-guided Fine-needle Biopsy
Published in Internal Medicine (15-01-2021)“…We herein report a case of recurrence of epithelial ovarian carcinoma 41 years after the primary surgery that was diagnosed by an endoscopic ultrasound-guided…”
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7
Changes in miRNA expressions in the injured small intestine of mice following high‑dose radiation exposure
Published in Molecular medicine reports (01-06-2020)“…The small intestine is one of the most highly regenerative and radiosensitive tissues in mammals, including humans. Exposure to high doses of ionizing…”
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Serum miR-375-3p increase in mice exposed to a high dose of ionizing radiation
Published in Scientific reports (22-01-2018)“…Exposure to high-doses of ionizing radiation (IR) leads to development of a strong acute radiation syndrome (ARS) in mammals. ARS manifests after a latency…”
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9
Characterization of a novel flooding stress-responsive alcohol dehydrogenase expressed in soybean roots
Published in Plant molecular biology (01-10-2011)“…Alcohol dehydrogenase (Adh) is the key enzyme in alcohol fermentation. We analyzed Adh expression in order to clarify the role of Adh of soybeans ( Glycine max…”
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10
Sarcoidosis with Splenic Involvement Diagnosed with Endoscopic Ultrasound-guided Fine-needle Aspiration
Published in Internal Medicine (15-08-2020)“…Splenic sarcoidosis is often diagnosed by splenectomy or an ultrasound-guided splenic biopsy. However, splenectomy is invasive and costly, and a percutaneous…”
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11
Cell‑to‑cell communication via extracellular vesicles among human pancreatic cancer cells derived from the same patient
Published in Molecular medicine reports (01-10-2018)“…Despite existing multimodal therapies, pancreatic cancer exhibits high metastatic capability and poor prognosis. Extracellular vesicles (EVs) are nanoparticles…”
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12
Multiomics and artificial intelligence enabled peripheral blood-based prediction of amnestic mild cognitive impairment
Published in Current research in translational medicine (01-01-2023)“…Since dementia is preventable with early interventions, biomarkers that assist in diagnosing early stages of dementia, such as mild cognitive impairment (MCI),…”
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13
Peroral cholangioscopy for the evaluation of bile duct stricture in hepatocellular carcinoma on a preoperative examination
Published in Journal of Rural Medicine (2023)“…Objective: Bile duct tumor thrombosis in hepatocellular carcinoma (HCC) is a relatively rare event with a poor prognosis. Furthermore, bile duct tumor thrombus…”
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14
Exosomes derived from SW480 colorectal cancer cells promote cell migration in HepG2 hepatocellular cancer cells via the mitogen-activated protein kinase pathway
Published in International journal of oncology (01-01-2016)“…Exosomes are membrane-derived extracellular vesicles that have recently been recognized as important mediators of intercellular communication. In the present…”
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Phytoestrogenic activity of blackcurrant (Ribes nigrum) anthocyanins is mediated through estrogen receptor alpha
Published in Molecular nutrition & food research (01-12-2015)“…SCOPE: Blackcurrants (Ribes nigrum L., Grossulariaceae) contain high amounts of anthocyanin polyphenols, which have antioxidant and anti‐carcinogenic health…”
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1,8-Cineole Ameliorates Steatosis of Pten Liver Specific KO Mice via Akt Inactivation
Published in International journal of molecular sciences (27-05-2015)“…Hepatocyte-specific Phosphatase and tensin homolog (Pten)-knockout (KO) mice exhibit hepatic lesions analogous to non-alcoholic steatohepatitis (NASH)…”
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Role of platelets on liver regeneration after 90% hepatectomy in mice
Published in Journal of hepatology (01-09-2008)“…Background/Aims Mortality after 90% partial hepatectomy in mice was associated with severe acute liver failure. Recently, we revealed that platelets have a…”
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Anthocyanin-rich blackcurrant extract inhibits proliferation of the MCF10A healthy human breast epithelial cell line through induction of G0/G1 arrest and apoptosis
Published in Molecular medicine reports (01-11-2017)“…Blackcurrants (Ribes nigrum L., Grossulariaceae) possess a high content of anthocyanin polyphenols, which have been demonstrated to exhibit beneficial effects…”
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Discovery, Primary, and Crystal Structures and Capacitation-related Properties of a Prostate-derived Heparin-binding Protein WGA16 from Boar Sperm
Published in The Journal of biological chemistry (27-02-2015)“…Mammalian sperm acquire fertility through a functional maturation process called capacitation, where sperm membrane molecules are drastically remodeled. In…”
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4-methylumbelliferone inhibits clonogenic potency by suppressing high molecular weight-hyaluronan in fibrosarcoma cells
Published in Oncology letters (01-04-2020)“…The inflammatory response is closely associated with cancer cell survival. It has been reported that inflammatory signaling cascades promote tumor survival and…”
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