Search Results - "Chiari, Conner C"
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The glucose transporter GLUT4 tethers RIG-I-like receptors to suppress antiviral immunity
Published in The Journal of immunology (1950) (01-05-2023)“…The current dogma of RIG-I-like receptor (RLR) regulation states that dysregulated interferon (IFN) production is predominantly repressed by reversible…”
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Journal Article -
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UBXN9 governs GLUT4-mediated spatial confinement of RIG-I-like receptors and signaling
Published in Nature immunology (20-11-2024)“…The cytoplasmic RIG-I-like receptors (RLRs) recognize viral RNA and initiate innate antiviral immunity. RLR signaling also triggers glycolytic reprogramming…”
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Journal Article