Search Results - "Chiari, Augusto"
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Determination of the Affinity of Drugs toward Serum Albumin by Measurement of the Quenching of the Intrinsic Tryptophan Fluorescence of the Protein
Published in Journal of pharmacy and pharmacology (01-01-1999)“…Binding of new chemical entities to serum proteins is an issue confronting pharmaceutical companies during development of potential therapeutic agents. Most…”
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Inhibition of acyl-CoA: cholesterol acyltransferase decreases apolipoprotein B-100-containing lipoprotein secretion from HepG2 cells
Published in Journal of lipid research (01-01-1996)“…There is evidence that the overproduction of apoB-100-containing lipoproteins by the liver is the underlying event in some forms of dyslipoproteinemia. This…”
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CORRECTION OF DYSLIPOPROTEINAEMIA OF CASEIN-FED RABBIT BY FCE 27677, A POTENT NOVEL ACAT INHIBITOR
Published in Pharmacological research (01-03-1996)“…Rabbits fed a wheat starch casein diet develop hypercholesterolaemia characterized by the plasma elevation of low density lipoprotein (LDL) that is caused by…”
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FCE 27677: A novel inhibitor of acyl-CoA:Cholesterol acyltransferase with potent oral hypolipidemic activity
Published in Pharmacological research (01-10-1995)“…FCE 27677 ([(−)N-[2,6-bis(1-methylethyl)phenyl]-N′-[(4R,5R)-2-(4-dimethylaminophenyl)-4,5 dimethyl-dioxolan-2-yl]methylurea) is a new systemically available…”
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N-Imidazolyl-4-chromanones, N-imidazolyl-1-tetralones, and their alcohols as hypolipemic agents raising high-density lipoproteins
Published in Journal of medicinal chemistry (01-03-1986)Get full text
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N-Imidazolylchroman-4-ones, N-imidazolyl-1-tetralones, and their alcohols as hypolipemic agents raising high-density lipoproteins
Published in Journal of medicinal chemistry (01-03-1986)“…A series of 3-(1-imidazolyl)chroman-4-ones and 2-(1-imidazolyl)-1-tetralones II, some of their alcohols, and some related compounds were synthesized and tested…”
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Effect of the antilipolytic compound acipimox on peroxisome marker enzymes, lipid pattern and biotransformation related functions in rat liver
Published in Pharmacological research communications (01-10-1985)“…The antilipolytic drug acipimox (5-methylpyrazine-2-carboxylic acid 4-oxide) was given to male rats for 1 week at 500, 1000 and 2000 mg/kg/day and for 2, 6 and…”
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