Search Results - "Chiara, Pozzi"
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One dose of SARS-CoV-2 vaccine exponentially increases antibodies in individuals who have recovered from symptomatic COVID-19
Published in The Journal of clinical investigation (15-06-2021)“…BACKGROUND. The COVID-19 vaccines currently in use require 2 doses to achieve optimal protection. Currently, there is no indication as to whether individuals…”
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Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation
Published in Nature medicine (01-04-2019)“…Several studies have investigated links between the gut microbiome and colorectal cancer (CRC), but questions remain about the replicability of biomarkers…”
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Analysis of immune, microbiota and metabolome maturation in infants in a clinical trial of Lactobacillus paracasei CBA L74-fermented formula
Published in Nature communications (01-06-2020)“…Mother’s milk is the best choice for infants nutrition, however when it is not available or insufficient to satisfy the needs of the infant, formula is…”
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SARS-CoV-2 serology in 4000 health care and administrative staff across seven sites in Lombardy, Italy
Published in Scientific reports (10-06-2021)“…Lombardy is the Italian region most affected by COVID-19. We tested the presence of plasma anti-SARS-CoV-2 IgG antibodies in 3985 employees across 7 healthcare…”
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Endogenous murine microbiota member Faecalibaculum rodentium and its human homologue protect from intestinal tumour growth
Published in Nature microbiology (01-03-2020)“…The microbiota has been shown to promote intestinal tumourigenesis, but a possible anti-tumourigenic effect has also been postulated. Here, we demonstrate that…”
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Bacteria-induced gap junctions in tumors favor antigen cross-presentation and antitumor immunity
Published in Science translational medicine (11-08-2010)“…Antigen-presenting dendritic cells (DCs) trigger the activation of cytotoxic CD8 T cells that target and eliminate cells with the antigen on their surface…”
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BNT162b2 vaccine induces antibody release in saliva: a possible role for mucosal viral protection?
Published in EMBO molecular medicine (09-05-2022)“…Vaccination against an airborne pathogen is very effective if it induces also the development of mucosal antibodies that can protect against infection. The…”
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Colorectal cancer, Vitamin D and microbiota: A double-blind Phase II randomized trial (ColoViD) in colorectal cancer patients
Published in Neoplasia (New York, N.Y.) (01-12-2022)“…Several studies suggest a role of gut microbiota in colorectal cancer (CRC) initiation and progression. Vitamin D (vitD) blood levels are also inversely…”
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Antibody Titer Correlates with Omicron Infection in Vaccinated Healthcare Workers
Published in Viruses (23-11-2022)“…The advent of vaccines against SARS-CoV-2 has drastically reduced the level of hospitalization with severe COVID-19 disease in infected individuals. However,…”
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Effectiveness of different booster vaccine combinations against SARS-CoV-2 during a six-month follow-up in Mexico and Argentina
Published in Frontiers in immunology (14-05-2024)“…Given the limited number of patients in Latin America who have received a booster dose against the COVID-19, it remains crucial to comprehend the effectiveness…”
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Microbiome as Mediator of Diet on Colorectal Cancer Risk: The Role of Vitamin D, Markers of Inflammation and Adipokines
Published in Nutrients (25-01-2021)“…Obesity and diet are associated with colorectal cancer (CRC) risk, and microbiome could mediate this risk factor. To investigate this interaction, we performed…”
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Ultra-low NOx diesel aftertreatment: An assessment by simulation
Published in Transportation engineering (Oxford) (01-09-2022)“…Upcoming Euro 7/VII regulations are under discussion, and, from available information, they will focus not only on reducing the current emission limits but…”
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Adverse Events to Comirnaty Vaccine Are Linked to Sex, Age and BMI: Should We Consider Reducing the Dose for Females?
Published in Vaccines (Basel) (22-02-2023)“…An important issue that is often neglected is the difference between male and female genders in response to medical treatments. In the context of COVID-19…”
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Short-Term Adverse Events and Antibody Response to the BNT162b2 SARS-CoV-2 Vaccine in 4156 Health Care Professionals
Published in Vaccines (Basel) (13-03-2022)“…Short-term adverse events are common following the BNT162b2 vaccine for SARS-Cov-2 and have been possibly associated with IgG response. We aimed to determine…”
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Human sialidase NEU4 long and short are extrinsic proteins bound to outer mitochondrial membrane and the endoplasmic reticulum, respectively
Published in Glycobiology (Oxford) (01-02-2010)“…Sialidases are widely distributed glycohydrolytic enzymes removing sialic acid residues from glycoconjugates. In mammals, several sialidases with different…”
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Efficacy of Six Different SARS-CoV-2 Vaccines during a Six-Month Follow-Up and Five COVID-19 Waves in Brazil and Mexico
Published in Vaccines (Basel) (01-04-2023)“…Comparisons among the different vaccines against SARS-CoV-2 are important to understand which type of vaccine provides more protection. This study aimed to…”
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A ‘Multiomic’ Approach of Saliva Metabolomics, Microbiota, and Serum Biomarkers to Assess the Need of Hospitalization in Coronavirus Disease 2019
Published in Gastro hep advances (2022)“…The SARS-CoV-2 pandemic has overwhelmed the treatment capacity of the health care systems during the highest viral diffusion rate. Patients reaching the…”
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Study of subcellular localization and proteolysis of ataxin-3
Published in Neurobiology of disease (01-05-2008)“…Abstract In this work we investigate subcellular localization and proteolytic cleavage of different forms of ataxin-3 (AT-3), the protein responsible for…”
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BNT162b2 vaccine induces antibody release in saliva: a possible role for mucosal viral protection?
Published in EMBO molecular medicine (19-04-2022)“…Vaccination against an airborne pathogen is very effective if it induces also the development of mucosal antibodies that can protect against infection. The…”
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Retrospective analysis to evaluate the efficacy and the safety of Bevacizumab in the treatment of recurrent malignant gliomas
Published in Translational medicine communications (14-04-2018)“…Background There is no consensus therapy recommended for recurrent malignant gliomas (MGs). In 2009, Bevacizumab (BEV) was approved by the FDA as single-agent…”
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