Search Results - "Chiara, Gaetano"

Differential neurochemical and behavioral adaptation to cocaine after response contingent and noncontingent exposure in the rat by Lecca, Daniele, Cacciapaglia, Fabio, Valentini, Valentina, Acquas, Elio, Di Chiara, Gaetano

“…In naive rats, passive administration of drugs of abuse preferentially increases extracellular dopamine (DA) in the nucleus accumbens (NAc) shell as compared…”
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Reciprocal responsiveness of nucleus accumbens shell and core dopamine to food- and drug-conditioned stimuli by Bassareo, Valentina, Musio, Paolo, Di Chiara, Gaetano

“…Rationale Drugs of abuse and palatable food share the ability to stimulate dopamine (DA) transmission in the nucleus accumbens shell. However, while the…”
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Lactoferrin- and antitransferrin-modified liposomes for brain targeting of the NK3 receptor agonist senktide: Preparation and in vivo evaluation by De Luca, Maria Antonietta, Lai, Francesco, Corrias, Francesco, Caboni, Pierluigi, Bimpisidis, Zisis, Maccioni, Elias, Fadda, Anna Maria, Di Chiara, Gaetano

“…[Display omitted] The aim of this work was to evaluate the capability of lactoferrin- and antitransferrin-modified long circulating liposomes to deliver the…”
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Impairment of acquisition of intravenous cocaine self-administration by RNA-interference of dopamine D1-receptors in the nucleus accumbens shell by Pisanu, Augusta, Lecca, Daniele, Valentini, Valentina, Bahi, Amine, Dreyer, Jean-Luc, Cacciapaglia, Fabio, Scifo, Andrea, Piras, Giovanna, Cadoni, Cristina, Di Chiara, Gaetano

“…Microdialysis during i.v. drug self-administration (SA) have implicated nucleus accumbens (NAc) shell DA in cocaine and heroin reinforcement. However, this…”
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Monitoring extracellular dopamine in the rat nucleus accumbens shell and core during acquisition and maintenance of intravenous WIN 55,212-2 self-administration by LECCA, Daniele, CACCIAPAGLIA, Fabio, VALENTINI, Valentina, DI CHIARA, Gaetano

“…WIN 55,212-2, a potent cannabinoid receptor 1 agonist, is self-administered by animals to evaluate abuse liability of cannabinoids, but to date no information…”
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Addiction theory matters—Why there is no dependence on caffeine or antidepressant medication by Heinz, Andreas, Daedelow, Laura S., Wackerhagen, Carolin, Di Chiara, Gaetano

“…With the development of the ICD‐11, the debate about classifying certain psychoactive substances such as antidepressant medication and caffeine as drugs of…”
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Does compulsion explain addiction? by Heinz, Andreas, Gutwinski, Stefan, Bahr, Nadja Samia, Spanagel, Rainer, Di Chiara, Gaetano

“…One of the leading drug addiction theories states that habits and the underlying neural process of a ventral to dorsal striatal shift are the building blocks…”
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Cannabinoid and Heroin Activation of Mesolimbic Dopamine Transmission by a Common $\mu_1$ Opioid Receptor Mechanism by Tanda, Gianluigi, Pontieri, Francesco E., Di Chiara, Gaetano

“…The effects of the active ingredient of Cannabis, $\Delta^9$-tetrahydrocannabinol ($\Delta^9$-THC), and of the highly addictive drug heroin on in vivo dopamine…”
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Influence of morphine sensitization on the responsiveness of mesolimbic and mesocortical dopamine transmission to appetitive and aversive gustatory stimuli by De Luca, Maria Antonietta, Bimpisidis, Zisis, Bassareo, Valentina, Di Chiara, Gaetano

“…Rationale Repeated treatment with morphine has been shown to sensitize rats to its stimulant effects on motor activity and mesolimbic dopamine (DA)…”
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Repeated exposure to JWH‐018 induces adaptive changes in the mesolimbic and mesocortical dopaminergic pathways, glial cells alterations, and behavioural correlates by Pintori, Nicholas, Castelli, Maria Paola, Miliano, Cristina, Simola, Nicola, Fadda, Paola, Fattore, Liana, Scherma, Maria, Ennas, Maria Grazia, Mostallino, Rafaela, Flore, Giovanna, De Felice, Marta, Sagheddu, Claudia, Pistis, Marco, Di Chiara, Gaetano, De Luca, Maria Antonietta

“…Background and Purpose Spice/K2 herbal mixtures, containing synthetic cannabinoids such as JWH‐018, have been marketed as marijuana surrogates since 2004…”
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Differential effects of intravenous R,S‐(±)‐3,4‐methylenedioxymethamphetamine (MDMA, Ecstasy) and its S(+)‐ and R(−)‐enantiomers on dopamine transmission and extracellular signal regulated kinase phosphorylation (pERK) in the rat nucleus accumbens shell and core by Acquas, Elio, Pisanu, Augusta, Spiga, Saturnino, Plumitallo, Antonio, Zernig, Gerald, Chiara, Gaetano Di

“…R,S(±)‐3,4‐methylenedioxymethamphetamine (R,S(±)‐MDMA, ‘Ecstasy’) is known to stimulate dopamine (DA) transmission in the nucleus accumbens (NAc). In order to…”
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Morphine-conditioned single-trial place preference : role of nucleus accumbens shell dopamine receptors in acquisition, but not expression by FENU, Sandro, SPINA, Liliana, RIVAS, Emilia, LONGONI, Rosanna, DI CHIARA, Gaetano

“…A large body of evidence indicates an involvement of the mesolimbic dopamine (DA) pathway innervating the ventral striatum in the motivational effects of drug…”
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Differences in dopamine responsiveness to drugs of abuse in the nucleus accumbens shell and core of Lewis and Fischer 344 rats by Cadoni, Cristina, Chiara, Gaetano Di

“…The use of inbred rat strains provides a tool to investigate the role of genetic factors in drug abuse. Two such strains are Lewis and Fischer 344 rats…”
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Preferential increase of extracellular dopamine in the rat nucleus accumbens shell as compared to that in the core during acquisition and maintenance of intravenous nicotine self-administration by Lecca, Daniele, Cacciapaglia, Fabio, Valentini, Valentina, Gronli, Janne, Spiga, Saturnino, Di Chiara, Gaetano

“…It has been reported that passive administration of nicotine increases preferentially extracellular dopamine (DA) release in the shell as compared to that in…”
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Differential impact of pavlovian drug conditioned stimuli on in vivo dopamine transmission in the rat accumbens shell and core and in the prefrontal cortex by Bassareo, Valentina, De Luca, Maria Antonietta, Di Chiara, Gaetano

“…Conditioned stimuli (CSs) by pavlovian association with reinforcing drugs (US) are thought to play an important role in the acquisition, maintenance and…”
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Changes in Dopamine Transmission in the Nucleus Accumbens Shell and Core during Ethanol and Sucrose Self-Administration by Bassareo, Valentina, Cucca, Flavia, Frau, Roberto, Di Chiara, Gaetano

“…Ethanol, like other substances of abuse, preferentially increases dopamine (DA) transmission in the rat nucleus accumbens (NAc) following passive…”
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Cumulative effect of norepinephrine and dopamine carrier blockade on extracellular dopamine increase in the nucleus accumbens shell, bed nucleus of stria terminalis and prefrontal cortex by Carboni, Ezio, Silvagni, Alessandra, Vacca, Cinzia, Chiara, Gaetano

“…We investigated, by microdialysis in various brain areas, the possibility that dopamine could be captured by the norepinephrine transporter when the dopamine…”
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Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs by Pontieri, Francesco E, Tanda, Gianluigi, Orzi, Francesco, Chiara, Gaetano Di

“…The question of whether nicotine, the neuroactive compound of tobacco, is addictive has been open to considerable scientific and public discussion. Although it…”
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Native CB1 receptor affinity, intrinsic activity and accumbens shell dopamine stimulant properties of third generation SPICE/K2 cannabinoids: BB-22, 5F-PB-22, 5F-AKB-48 and STS-135 by De Luca, Maria Antonietta, Castelli, M. Paola, Loi, Barbara, Porcu, Alessandra, Martorelli, Mariella, Miliano, Cristina, Kellett, Kathryn, Davidson, Colin, Stair, Jacqueline L., Schifano, Fabrizio, Di Chiara, Gaetano

“…In order to investigate the in vivo dopamine (DA) stimulant properties of selected 3rd generation Spice/K2 cannabinoids, BB-22, 5F-PB-22, 5F-AKB-48 and…”
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3‐[3‐(Phenalkylamino)cyclohexyl]phenols: Synthesis, biological activity, and in silico investigation of a naltrexone‐derived novel class of MOR‐antagonists by Tocco, Graziella, Laus, Antonio, Vanejevs, Maksims, Ture, Anastasija, Mostallino, Rafaela, Pintori, Nicholas, De Luca, Maria Antonietta, Castelli, M. Paola, Di Chiara, Gaetano

“…The development of novel μ‐opioid receptor (MOR) antagonists is one of the main objectives of drug discovery and development. Based on a simplified version of…”
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