Search Results - "Chiappe, Diego"
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1
A quantitative telomeric chromatin isolation protocol identifies different telomeric states
Published in Nature communications (25-11-2013)“…Telomere composition changes during tumourigenesis, aging and in telomere syndromes in a poorly defined manner. Here we develop a quantitative telomeric…”
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2
The early communication stages between serine proteases and enterovirus capsids in the race for viral disintegration
Published in Communications biology (09-08-2024)“…Serine proteases are important environmental contributors of enterovirus biocontrol. However, the structural features of molecular interaction accounting for…”
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3
Hypoxic Incubation Conditions for Optimized Manufacture of Tenocyte-Based Active Pharmaceutical Ingredients of Homologous Standardized Transplant Products in Tendon Regenerative Medicine
Published in Cells (Basel, Switzerland) (25-10-2021)“…Human fetal progenitor tenocytes (hFPT) produced in defined cell bank systems have recently been characterized and qualified as potential therapeutic cell…”
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4
Differential Proteomics via Probabilistic Peptide Identification Scores
Published in Analytical chemistry (Washington) (15-01-2005)“…Relative quantitation is key to enable differential proteomics and hence answer biological questions by comparing samples. Classical approaches involve stable…”
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5
The mouse SWISS-2D PAGE database: a tool for proteomics study of diabetes and obesity
Published in Proteomics (Weinheim) (01-01-2001)“…A number of two‐dimensional electrophoresis (2‐DE) reference maps from mouse samples have been established and could be accessed through the internet. An…”
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6
Beyond Unpredictability: The Importance of Reproducibility in Understanding the Protein Corona of Nanoparticles
Published in Bioconjugate chemistry (17-10-2018)“…While it is well established that the surface of a nanoparticle plays a pivotal role for the protein corona, the vast number of proteins present in biological…”
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7
The establishment of a human liver nuclei two-dimensional electrophoresis reference map
Published in Electrophoresis (01-10-2000)“…This short communication describes the establishment of a two‐dimensional electrophoresis (2‐DE) reference map of nuclear proteins isolated from human liver…”
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Proteomic and Lipidomic Investigation of an Ex-Vivo Human Model of Sickle Cell Disease Erythropoiesis and Patient Erythrocytes Reveals the Abnormal Localization and Dysfunction of the Proteasome, Disrupted Antioxidant Defenses and Altered Lipid Profiles
Published in Blood (15-11-2022)Get full text
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9
Phosphorylation at S87 is enhanced in synucleinopathies, inhibits alpha-synuclein oligomerization, and influences synuclein-membrane interactions
Published in The Journal of neuroscience (03-03-2010)“…Increasing evidence suggests that phosphorylation may play an important role in the oligomerization, fibrillogenesis, Lewy body (LB) formation, and…”
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10
Lysine acetylation stoichiometry and proteomics analyses reveal pathways regulated by sirtuin 1 in human cells
Published in The Journal of biological chemistry (03-11-2017)“…Lysine acetylation is a widespread posttranslational modification affecting many biological pathways. Recent studies indicate that acetylated lysine residues…”
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11
Quantitative Mass Spectrometry Reveals Plasticity of Metabolic Networks in Mycobacterium smegmatis
Published in Molecular & cellular proteomics (01-11-2014)“…Mycobacterium tuberculosis has a remarkable ability to persist within the human host as a clinically inapparent or chronically active infection. Fatty acids…”
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12
Analysis of the S. pombe Meiotic Proteome Reveals a Switch from Anabolic to Catabolic Processes and Extensive Post-transcriptional Regulation
Published in Cell reports (Cambridge) (22-01-2019)“…Meiotic progression in S. pombe is regulated by stage-specific gene expression and translation, changes in RNA stability, expression of anti-sense transcripts,…”
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13
Protein Corona: Impact of Lymph Versus Blood in a Complex In Vitro Environment
Published in Small (Weinheim an der Bergstrasse, Germany) (01-08-2017)“…In biological environments, the surface of nanoparticles (NPs) are modified by protein corona (PC) that determines their biological behavior. Unfortunately, in…”
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14
Correction to Beyond Unpredictability: The Importance of Reproducibility in Understanding the Protein Corona of Nanoparticles
Published in Bioconjugate chemistry (19-06-2019)Get full text
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15
An interplay between the p38 MAPK pathway and AUBPs regulates c-fos mRNA stability during mitogenic stimulation
Published in Biochemical journal (01-04-2015)“…Mitogen-activated protein kinase (MAPK) pathways constitute key regulatory elements linking extracellular stimuli to nuclear gene expression. Immediate-early…”
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16
Tissue Transglutaminase-mediated Glutamine Deamidation of β-Amyloid Peptide Increases Peptide Solubility, Whereas Enzymatic Cross-linking and Peptide Fragmentation May Serve as Molecular Triggers for Rapid Peptide Aggregation
Published in The Journal of biological chemistry (08-04-2011)“…Tissue transglutaminase (TGase) has been implicated in a number of cellular processes and disease states, where the enzymatic actions of TGase may serve in…”
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17
Electron Capture and Transfer Dissociation: Peptide Structure Analysis at Different Ion Internal Energy Levels
Published in Journal of the American Society for Mass Spectrometry (01-04-2009)“…We decoupled electron-transfer dissociation (ETD) and collision-induced dissociation of charge-reduced species (CRCID) events to probe the lifetimes of…”
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18
Dissecting the Mechanisms of Tissue Transglutaminase-induced Cross-linking of α-Synuclein: IMPLICATIONS FOR THE PATHOGENESIS OF PARKINSON DISEASE
Published in The Journal of biological chemistry (08-05-2009)“…Tissue transglutaminase (tTG) has been implicated in the pathogenesis of Parkinson disease (PD). However, exactly how tTG modulates the structural and…”
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19
Characterization of the surfaceome of the metal-reducing bacterium Desulfotomaculum reducens
Published in Frontiers in microbiology (19-08-2014)“…Desulfotomaculum reducens strain MI-1 is a Gram-positive, sulfate-reducing bacterium also capable of reducing Fe(III). Metal reduction in Gram-positive…”
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Dissecting the Mechanisms of Tissue Transglutaminase-induced Cross-linking of α-Synuclein
Published in The Journal of biological chemistry (08-05-2009)“…Tissue transglutaminase (tTG) has been implicated in the pathogenesis of Parkinson disease (PD). However, exactly how tTG modulates the structural and…”
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