Search Results - "Chiao, Jen Wei"

A meta-analysis of CAG (cytarabine, aclarubicin, G-CSF) regimen for the treatment of 1029 patients with acute myeloid leukemia and myelodysplastic syndrome by Wei, Guoqing, Ni, Wanmao, Chiao, Jen-wei, Cai, Zhen, Huang, He, Liu, Delong

“…The regimen of cytarabine, aclarubicin and G-CSF (CAG) has been widely used in China and Japan for treatment of acute myeloid leukemia (AML) and…”
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Phenethyl isothiocyanate and paclitaxel synergistically enhanced apoptosis and alpha-tubulin hyperacetylation in breast cancer cells by Cang, Shundong, Ma, Yuehua, Chiao, Jen-Wei, Liu, Delong

“…Combination of phenethyl isothiocyanate (PEITC) and paclitaxel (taxol) has been shown to work synergistically to increase apoptosis and cell cycle arrest in…”
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Effect of phenylhexyl isothiocyanate on aberrant histone H3 methylation in primary human acute leukemia by Zou, Yong, Ma, Xudong, Huang, Yiqun, Hong, Lingling, Chiao, Jen-wei

“…We have previously studied the histone acetylation in primary human leukemia cells. However, histone H3 methylation in these cells has not been characterized…”
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Growth inhibition of a spectrum of bacterial and fungal pathogens by sulforaphane, an isothiocyanate product found in broccoli and other cruciferous vegetables by Johansson, Noelle L, Pavia, Charles S, Chiao, Jen Wei

“…In addition to its documented antitumor effects, previous in vitro and in vivo infectivity experiments have shown that sulforaphane (SFN), an isothiocyanate…”
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Reactivating aberrantly hypermethylated p15 gene in leukemic T cells by a phenylhexyl isothiocyanate mediated inter-active mechanism on DNA and chromatin by Jiang, Shaohong, Ma, Xudong, Huang, Yiqun, Xu, Yunlu, Zheng, Ruiji, Chiao, Jen-Wei

“…We have previously demonstrated that phenylhexyl isothiocyanate (PHI), a synthetic isothiocyanate, inhibits histone deacetylases and remodels chromatins to…”
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Phenylhexyl isothiocyanate has dual function as histone deacetylase inhibitor and hypomethylating agent and can inhibit myeloma cell growth by targeting critical pathways by Lu, Quanyi, Lin, Xianghua, Feng, Jean, Zhao, Xiangmin, Gallagher, Ruth, Lee, Marietta Y, Chiao, Jen-Wei, Liu, Delong

“…Histone deacetylase (HDAC) inhibitors are a new class of chemotherapeutic agents. Our laboratory has recently reported that phenylhexyl isothiocyanate (PHI), a…”
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Sulforaphane induces growth arrest and apoptosis in human ovarian cancer cells by Chuang, Linus T, Moqattash, Satei T, Gretz, Herbert F, Nezhat, Farr, Rahaman, Jamal, Chiao, Jen-Wei

“…Isothiocyanates (ITC) from broccoli and other cruciferous vegetables have long been shown to have chemopreventive properties, as demonstrated in cancer models…”
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Development of human prostate cancer stem cells involves epigenomic alteration and PI3K/AKT pathway activation by Wu, Jingjing, Cang, Shundong, Liu, Christina, Ochiai, Whitman, Chiao, Jen Wei

“…Human prostate cancer spheres endowed with stem cell properties have been obtained from androgen-dependent cell line LNCaP after exposure to an epigenomic…”
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Ingestion of an isothiocyanate metabolite from cruciferous vegetables inhibits growth of human prostate cancer cell xenografts by apoptosis and cell cycle arrest by Chiao, Jen Wei, Wu, Hongyan, Ramaswamy, Gita, Conaway, C. Clifford, Chung, Fung-Lung, Wang, Longgui, Liu, Delong

“…Epidemiological surveys indicate that intake of cruciferous vegetables is inversely related to prostate cancer incidence, although the responsible dietary…”
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Targeting cell cycle machinery as a molecular mechanism of sulforaphane in prostate cancer prevention by Wang, Longgui, Liu, Delong, Ahmed, Tauseef, Chung, Fung-Lung, Conaway, Clifford, Chiao, Jen-Wei

“…Epidemiological studies recently concluded that consumption of cruciferous vegetables such as broccoli, cabbage, and cauliflower, etc. is inversely related to…”
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What causes prostate cancer-learning from a tragedy by Chiao, Jen Wei

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Epigenetic Mechanism of Growth Inhibition Induced by Phenylhexyl Isothiocyanate in Prostate Cancer Cells by Beklemisheva, Anastasia A, Fang, Yuqiang, Feng, Jingyang, Ma, Xudong, Dai, Wei, Chiao, Jen Wei

“…Background: Isothiocyanates, the constituents of cruciferous vegetables, may be able to prevent prostate cancer. The hypothesis that they could remodel…”
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Synergistic effect of paclitaxel and epigenetic agent phenethyl isothiocyanate on growth inhibition, cell cycle arrest and apoptosis in breast cancer cells by Liu, Katherine, Cang, Shundong, Ma, Yuehua, Chiao, Jen Wei

“…This study examined whether combining paclitaxel (taxol) with a novel epigenetic agent phenethyl isothiocyanate (PEITC) will yield a synergistic effect on…”
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Phenylhexyl isothiocyanate (PHI) regulates histone methylation and acetylation and induces apoptosis in SMMC-7721 cells by Huang, Yi-Qun, Ma, Xu-Dong, Lai, Ya-Dong, Wang, Xiao-Zhong, Chiao, Jen-Wei, Liu, De-Long

“…To investigate the effects of PHI on histone acetylation and methylation in hepatocellular carcinoma line SMMC-7721 cells. Apoptosis was measured by TUNNEL…”
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Experiment study of PHI on histone methylation and acetylation in Molt-4 cells by Huang, Yi-Qun, Ma, Xu-Dong, Zhen, Rui-Ji, Chiao, Jen-Wei, Liu, De-Long

“…To investigate the effect of phenyl-hexyl isothiocyanate (PHI) on acetylation and methylation of histone in acute lymphoblastic leukemia cell line Molt4. The…”
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Natura-alpha, a novel STAT3-Y705 inhibitor in treating systemic lupus erythematosus in NZB/W female mice (P5157) by Wang, Longgui, Han, Liying, Fallon, John, Tsao, Allen, Chiao, Jen-Wei

“…Abstract Systemic lupus erythematosus (SLE) is a complex autoimmune disease. Increases in Th1/Th17 cells, and decreases in Treg cells, have been observed in…”
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Mitochondrial structure alteration in human prostate cancer cells upon initial interaction with a chemopreventive agent phenethyl isothiocyanate by Xue, Chengsen, Pasolli, Hilda A, Piscopo, Irene, Gros, Daniel J, Liu, Christina, Chen, Yamei, Chiao, Jen Wei

“…Phenethyl isothiocyanate (PEITC), present naturally in cruciferous vegetables, is a chemopreventive agent. It blocks initiation and post-initiation progression…”
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Human Leukemia Cell Maturation Induced by a T-Cell Lymphokine Isolated from Medium Conditioned by Normal Lymphocytes by Leung, Kiu, Chiao, Jen Wei

“…Human myelogeneous leukemia cells in liquid culture can be induced to mature along the monocyte/macrophage pathway by a maturation inducer derived from the…”
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A meta-analysis of CAG by Cai, Zhen, Liu, Delong, Chiao, Jen-wei, Wei, Guoqing, Huang, He, Ni, Wanmao

“…The regimen of cytarabine, aclarubicin and G-CSF (CAG) has been widely used in China and Japan for treatment of acute myeloid leukemia (AML) and…”
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The Epigenetic Effect of Phenylhexyl Isothiocyanate on Histone Acetylation in Patients with Acute Leukemia and Non-Leukemic Disorders by Xiao, Liyun, Ma, Xudong, Huang, Yiqun, Zhen, Ruiji, Ye, Xiaoling, Chiao, Jen-Wei, Liu, Delong

“…Phenyhexyl isothiocyanate (PHI) has been shown to inhibit histone deacetylation in leukemia cell lines in vitro and in animal models. In this study we examined…”
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