Search Results - "Chiang, Ming Sum R"

Preclinical pharmacology of glucosylceramide synthase inhibitor venglustat in a GBA-related synucleinopathy model by Viel, Catherine, Clarke, Jennifer, Kayatekin, Can, Richards, Amy M., Chiang, Ming Sum R., Park, Hyejung, Wang, Bing, Shihabuddin, Lamya S., Sardi, S. Pablo

“…Mutations in GBA , the gene encoding the lysosomal enzyme glucocerebrosidase (GCase), represent the greatest genetic risk factor for developing…”
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Exosome reporter mice reveal the involvement of exosomes in mediating neuron to astroglia communication in the CNS by Men, Yuqin, Yelick, Julia, Jin, Shijie, Tian, Yang, Chiang, Ming Sum R., Higashimori, Haruki, Brown, Eoin, Jarvis, Rachel, Yang, Yongjie

“…Astroglia play active and diverse roles in modulating neuronal/synaptic functions in the CNS. How these astroglial functions are regulated, especially by…”
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Molecular and Functional Properties of Regional Astrocytes in the Adult Brain by Morel, Lydie, Chiang, Ming Sum R, Higashimori, Haruki, Shoneye, Temitope, Iyer, Lakshmanan K, Yelick, Julia, Tai, Albert, Yang, Yongjie

“…The molecular signature and functional properties of astroglial subtypes in the adult CNS remain largely undefined. By using translational ribosome affinity…”
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Differential Proliferation and Maturation of Subcortical Astrocytes During Postnatal Development by Shoneye, Temitope, Orrego, Alessandra Tamashiro, Jarvis, Rachel, Men, Yuqin, Chiang, Ming Sum R, Yang, Yongjie

“…Astrocytes exhibit a region-dependent molecular and functional heterogeneity in the CNS. Although cortical astrocytes proliferate robustly during the first…”
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Molecular analysis of acute and chronic reactive astrocytes in the pilocarpine model of temporal lobe epilepsy by Clasadonte, Jerome, Morel, Lydie, Barrios-Camacho, Camila M, Chiang, Ming Sum, Zhang, Jinhua, Iyer, Lakshmanan, Haydon, Philip G, Yang, Yongjie

“…Abstract Astroglia, the most abundant glial cells in the mammalian central nervous system (CNS), are considered an emerging key player in seizure induction and…”
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Selective Deletion of Astroglial FMRP Dysregulates Glutamate Transporter GLT1 and Contributes to Fragile X Syndrome Phenotypes In Vivo by Higashimori, Haruki, Schin, Christina S, Chiang, Ming Sum R, Morel, Lydie, Shoneye, Temitope A, Nelson, David L, Yang, Yongjie

“…How the loss of fragile X mental retardation protein (FMRP) in different brain cell types, especially in non-neuron glial cells, induces fragile X syndrome…”
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Astroglial FMRP modulates synaptic signaling and behavior phenotypes in FXS mouse model by Jin, Shan‐Xue, Higashimori, Haruki, Schin, Christina, Tamashiro, Alessandra, Men, Yuqin, Chiang, Ming Sum R, Jarvis, Rachel, Cox, Dan, Feig, Larry, Yang, Yongjie

“…Fragile X syndrome (FXS) is one of the most common inherited intellectual disability (ID) disorders, in which the loss of FMRP protein induces a range of…”
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