Search Results - "Chiacchio, Teresa"

Immune characterization of the HBHA-specific response in Mycobacterium tuberculosis-infected patients with or without HIV infection by Chiacchio, Teresa, Delogu, Giovanni, Vanini, Valentina, Cuzzi, Gilda, De Maio, Flavio, Pinnetti, Carmela, Sampaolesi, Alessandro, Antinori, Andrea, Goletti, Delia

“…RD1-based Interferon-γ Release Assays (IGRAs) cannot distinguish latent from active tuberculosis (TB) disease. Conversely, a positive response to…”
Get full text

Evaluation of IP-10 in Quantiferon-Plus as biomarker for the diagnosis of latent tuberculosis infection by Petrone, Linda, Vanini, Valentina, Chiacchio, Teresa, Petruccioli, Elisa, Cuzzi, Gilda, Schininà, Vincenzo, Palmieri, Fabrizio, Ippolito, Giuseppe, Goletti, Delia

“…The QuantiFERON-TB Gold Plus (QFT-Plus) is a new test for latent tuberculosis infection (LTBI) diagnosis, in which has been added a new tube containing shorter…”
Get full text

Impaired IFN-α-mediated signal in dendritic cells differentiates active from latent tuberculosis by Parlato, Stefania, Chiacchio, Teresa, Salerno, Debora, Petrone, Linda, Castiello, Luciano, Romagnoli, Giulia, Canini, Irene, Goletti, Delia, Gabriele, Lucia

“…Individuals exposed to Mycobacterium tuberculosis (Mtb) may be infected and remain for the entire life in this condition defined as latent tuberculosis…”
Get full text

Mycobacterium tuberculosis Immune Response in Patients With Immune-Mediated Inflammatory Disease by Petruccioli, Elisa, Petrone, Linda, Chiacchio, Teresa, Farroni, Chiara, Cuzzi, Gilda, Navarra, Assunta, Vanini, Valentina, Massafra, Umberto, Lo Pizzo, Marianna, Guggino, Giuliana, Caccamo, Nadia, Cantini, Fabrizio, Palmieri, Fabrizio, Goletti, Delia

“…Subjects with immune-mediated inflammatory diseases (IMID), such as rheumatoid arthritis (RA), have an intrinsic higher probability to develop…”
Get full text

Interplay of DDP4 and IP-10 as a Potential Mechanism for Cell Recruitment to Tuberculosis Lesions by Blauenfeldt, Thomas, Petrone, Linda, Del Nonno, Franca, Baiocchini, Andrea, Falasca, Laura, Chiacchio, Teresa, Bondet, Vincent, Vanini, Valentina, Palmieri, Fabrizio, Galluccio, Gianni, Casrouge, Armanda, Eugen-Olsen, Jesper, Albert, Matthew L, Goletti, Delia, Duffy, Darragh, Ruhwald, Morten

“…is one of the world's most successful pathogens equipped to establish itself within the human host as a subclinical infection without overt disease. Unable to…”
Get full text

Methylated HBHA produced in M. smegmatis discriminates between active and non-active tuberculosis disease among RD1-responders by Delogu, Giovanni, Chiacchio, Teresa, Vanini, Valentina, Butera, Ornella, Cuzzi, Gilda, Bua, Alessandra, Molicotti, Paola, Zanetti, Stefania, Lauria, Francesco Nicola, Grisetti, Susanna, Magnavita, Nicola, Fadda, Giovanni, Girardi, Enrico, Goletti, Delia

“…A challenge in tuberculosis (TB) research is to develop a new immunological test that can help distinguish, among subjects responsive to QuantiFERON TB Gold In…”
Get full text

Higher frequency of T-cell response to M. tuberculosis latency antigen Rv2628 at the site of active tuberculosis disease than in peripheral blood by Chiacchio, Teresa, Petruccioli, Elisa, Vanini, Valentina, Butera, Ornella, Cuzzi, Gilda, Petrone, Linda, Matteucci, Giuseppe, Lauria, Francesco Nicola, Franken, Kees L M C, Girardi, Enrico, Ottenhoff, Tom H M, Goletti, Delia

“…Due to the invasive nature of the procedures involved, most studies of Mycobacterium tuberculosis (Mtb)-specific immunity in humans have focused on the…”
Get full text

IP-10 detection in urine is associated with lung diseases by Cannas, Angela, Calvo, Ludovica, Chiacchio, Teresa, Cuzzi, Gilda, Vanini, Valentina, Lauria, Francesco N, Pucci, Luigia, Girardi, Enrico, Goletti, Delia

“…Blood cytokines and chemokines have been proposed as biomarkers for tuberculosis (TB). Recently, some immune mediators found in the urine of patients with…”
Get full text

New tools for detecting latent tuberculosis infection: evaluation of RD1-specific long-term response by Butera, Ornella, Chiacchio, Teresa, Carrara, Stefania, Casetti, Rita, Vanini, Valentina, Meraviglia, Serena, Guggino, Giuliana, Dieli, Francesco, Vecchi, Marco, Lauria, Francesco N, Marruchella, Almerico, Laurenti, Patrizia, Singh, Mahavir, Caccamo, Nadia, Girardi, Enrico, Goletti, Delia

“…Interferon-gamma (IFN-gamma) release assays (IGRAs) were designed to detect latent tuberculosis infection (LTBI). However, discrepancies were found between the…”
Get full text

Characterization of the CD4 and CD8 T-Cell Response in the QuantiFERON-TB Gold Plus Kit by Petruccioli, Elisa, Chiacchio, Teresa, Pepponi, Ilaria, Vanini, Valentina, Urso, Rocco, Cuzzi, Gilda, Barcellini, Lucia, Palmieri, Fabrizio, Cirillo, Daniela, Ippolito, Giuseppe, Goletti, Delia

“…Abstract Objective/Background QuantiFERON-TB Gold In-Tube (QFT-GIT, Qiagen, Hilden, Germany) is an interferon-γ (IFN-γ) release assay designed to detect latent…”
Get full text

Modulation of Interferon-Gamma Response to QuantiFERON-TB-Plus Detected by Enzyme-Linked Immunosorbent Assay in Patients With Active and Latent Tuberculosis Infection by Petruccioli, Elisa, Vanini, Valentina, Chiacchio, Teresa, Cirillo, Daniela, Palmieri, Fabrizio, Ippolito, Giuseppe, Goletti, Delia

“…Abstract Objective/Background Interferon (IFN)-γ-release assays (IGRAs) are designed for the diagnosis of tuberculosis (TB) infection. The new IGRA called…”
Get full text

Modulation of CD4 and CD8 Response to QuantiFERON-TB Plus in Patients With Active Tuberculosis and Latent Tuberculosis Infection Followed Over Time During Treatment by Chiacchio, Teresa, Petruccioli, Elisa, Pepponi, Ilaria, Vanini, Valentina, Gualano, Gina, Cirillo, Daniela, Palmieri, Fabrizio, Ippolito, Giuseppe, Goletti, Delia

“…Abstract Objective/Background Interferon (IFN)-γ release assays (IGRA) are designed for diagnosing tuberculosis (TB) infection. The new IGRA, QuantiFERON-TB…”
Get full text

First characterization of the CD4 and CD8 T-cell responses to QuantiFERON-TB Plus by Petruccioli, Elisa, Chiacchio, Teresa, Pepponi, Ilaria, Vanini, Valentina, Urso, Rocco, Cuzzi, Gilda, Barcellini, Lucia, Cirillo, Daniela Maria, Palmieri, Fabrizio, Ippolito, Giuseppe, Goletti, Delia

“…Summary Introduction QuantiFERON® -TB Gold Plus (QFT-Plus) is the new generation of QuantiFERON-TB Gold In-Tube test to identify latent tuberculosis infection…”
Get full text

Polyfunctional T-cells and effector memory phenotype are associated with active TB in HIV-infected patients by Chiacchio, Teresa, Petruccioli, Elisa, Vanini, Valentina, Cuzzi, Gilda, Pinnetti, Carmela, Sampaolesi, Alessandro, Antinori, Andrea, Girardi, Enrico, Goletti, Delia

“…Summary Objectives Polyfunctional T-cells associate with chronic viral infection control while their involvement in tuberculosis (TB) is unclear. We evaluated…”
Get full text

Effect of HIV-infection on QuantiFERON-plus accuracy in patients with active tuberculosis and latent infection by Petruccioli, Elisa, Chiacchio, Teresa, Navarra, Assunta, Vanini, Valentina, Cuzzi, Gilda, Cimaglia, Claudia, Codecasa, Luigi Ruffo, Pinnetti, Carmela, Riccardi, Niccolò, Palmieri, Fabrizio, Antinori, Andrea, Goletti, Delia

“…•QFT-Plus has similar sensitivity for active TB detection independently of HIV infection.•CD4 count does not influence IFNγ values of QFT-Plus in HIV-TB…”
Get full text

Combined use of Quantiferon and HBHA-based IGRA supports tuberculosis diagnosis and therapy management in children by Sali, Michela, Buonsenso, Danilo, D'Alfonso, Pamela, De Maio, Flavio, Ceccarelli, Manuela, Battah, Basem, Palucci, Ivana, Chiacchio, Teresa, Goletti, Delia, Sanguinetti, Maurizio, Valentini, Piero, Delogu, Giovanni

“…Interferon-γ release assays (IGRA) are designed for diagnosis of tuberculosis (TB) infection, and do not discriminate latent TB infection (LTBI) from active…”
Get full text

Effect of therapy on Quantiferon-Plus response in patients with active and latent tuberculosis infection by Petruccioli, Elisa, Chiacchio, Teresa, Vanini, Valentina, Cuzzi, Gilda, Codecasa, Luigi Ruffo, Ferrarese, Maurizio, Schininà, Vincenzo, Palmieri, Fabrizio, Ippolito, Giuseppe, Goletti, Delia

“…Lack of biomarkers for treatment monitoring is listed among the main requirements for next generation assays, as identified globally among tuberculosis (TB)…”
Get full text

Impact of antiretroviral and tuberculosis therapies on CD4+ and CD8+ HIV/M. tuberculosis-specific T-cell in co-infected subjects by Chiacchio, Teresa, Petruccioli, Elisa, Vanini, Valentina, Cuzzi, Gilda, La Manna, Marco Pio, Orlando, Valentina, Pinnetti, Carmela, Sampaolesi, Alessandro, Antinori, Andrea, Caccamo, Nadia, Goletti, Delia

“…•ART and TB therapies increase the CD4+T-cells.•ART and TB therapies increase the Mtb-specific CD4+T-cells in HIV-LTBI.•ART and TB therapies increase the…”
Get full text

Characterization of QuantiFERON-TB-Plus results in latent tuberculosis infected patients with or without immune-mediated inflammatory diseases by Chiacchio, Teresa, Petruccioli, Elisa, Vanini, Valentina, Cuzzi, Gilda, Massafra, Umberto, Baldi, Gianpiero, Navarra, Assunta, Scrivo, Rossana, Mastroianni, Claudio, Sauzullo, Ilaria, Esposito, Carmela, Palmieri, Fabrizio, Cantini, Fabrizio, Goletti, Delia

“…•IFN-γ response to QFT-P is lower in IMID-LTBI compared to LTBI without IMID.•IMID status does not impact the ability to respond simultaneously to TB1 and…”
Get full text

High urine IP-10 levels associate with chronic HCV infection by Petrone, Linda, Chiacchio, Teresa, Vanini, Valentina, Petruccioli, Elisa, Cuzzi, Gilda, Di Giacomo, Cristina, Pucci, Luigia, Montalbano, Marzia, Lionetti, Raffaella, Testa, Angela, Lapa, Daniele, Navarra, Assunta, Visco-Comandini, Ubaldo, Goletti, Delia

“…Summary Objectives Independent of IL-28B polymorphisms, blood IP-10 is a promising biomarker for predicting therapy response in chronic HCV infection. Urine…”
Get full text