Search Results - "Chia, Sook Yoong"

The RNA-binding protein HuR is a negative regulator in adipogenesis by Siang, Diana Teh Chee, Lim, Yen Ching, Kyaw, Aung Maung Maung, Win, Khaing Nwe, Chia, Sook Yoong, Degirmenci, Ufuk, Hu, Xiang, Tan, Bryan C., Walet, Arcinas Camille Esther, Sun, Lei, Xu, Dan

“…Human antigen R (HuR) is an essential regulator of RNA metabolism, but its function in metabolism remains unclear. This study identifies HuR as a major…”
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Dynamic transcriptome changes during adipose tissue energy expenditure reveal critical roles for long noncoding RNA regulators by Bai, Zhiqiang, Chai, Xiao-Ran, Yoon, Myeong Jin, Kim, Hye-Jin, Lo, Kinyui Alice, Zhang, Zhi-Chun, Xu, Dan, Siang, Diana Teh Chee, Walet, Arcinas Camille Esther, Xu, Shao-Hai, Chia, Sook-Yoong, Chen, Peng, Yang, Hongyuan, Ghosh, Sujoy, Sun, Lei

“…Enhancing brown fat activity and promoting white fat browning are attractive therapeutic strategies for treating obesity and associated metabolic disorders. To…”
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Increased expression of pathological markers in Parkinson's disease dementia post-mortem brains compared to dementia with Lewy bodies by Tu, Haitao, Zhang, Zhi Wei, Qiu, Lifeng, Lin, Yuning, Jiang, Mei, Chia, Sook-Yoong, Wei, Yanfei, Ng, Adeline S L, Reynolds, Richard, Tan, Eng-King, Zeng, Li

“…Parkinson's disease (PD) and dementia with Lewy bodies (DLB) are common age-related neurodegenerative diseases comprising Lewy body spectrum disorders…”
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De novo reconstruction of human adipose transcriptome reveals conserved lncRNAs as regulators of brown adipogenesis by Ding, Chunming, Lim, Yen Ching, Chia, Sook Yoong, Walet, Arcinas Camille Esther, Xu, Shaohai, Lo, Kinyui Alice, Zhao, Yanling, Zhu, Dewen, Shan, Zhihui, Chen, Qingfeng, Leow, Melvin Khee-Shing, Xu, Dan, Sun, Lei

“…Obesity has emerged as an alarming health crisis due to its association with metabolic risk factors such as diabetes, dyslipidemia, and hypertension. Recent…”
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Amyloid precursor protein intracellular domain-dependent regulation of FOXO3a inhibits adult hippocampal neurogenesis by Jiang, Mei, Vanan, Sarivin, Tu, Hai-Tao, Zhang, Wei, Zhang, Zhi-Wei, Chia, Sook-Yoong, Jang, Se Eun, Zeng, Xiao-Xia, Yu, Wei-Ping, Xu, Jie, Guo, Kai-Hua, Zeng, Li

“…The amyloid precursor protein (APP) intracellular domain (AICD) is a metabolic by-product of APP produced through sequential proteolytic cleavage by α-, β-,…”
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Dynamic DNA methylation landscape defines brown and white cell specificity during adipogenesis by Lim, Yen Ching, Chia, Sook Yoong, Jin, Shengnan, Han, Weiping, Ding, Chunming, Sun, Lei

“…Abstract Objective DNA methylation may be a stable epigenetic contributor to defining fat cell lineage. Methods We performed reduced representation bisulfite…”
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Altered Cerebrospinal Fluid Exosomal microRNA Levels in Young-Onset Alzheimer’s Disease and Frontotemporal Dementia by Tan, Yi Jayne, Wong, Benjamin Y.X., Vaidyanathan, Ramanathan, Sreejith, Sivaramapanicker, Chia, Sook Yoong, Kandiah, Nagaendran, Ng, Adeline S.L., Zeng, Li

“…Background: micro-RNAs (miRNAs) are stable, small, non-coding RNAs enriched in exosomes. Their variation in levels according to different disease etiologies…”
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Altered striatal dopamine levels in Parkinson’s disease VPS35 D620N mutant transgenic aged mice by Vanan, Sarivin, Zeng, Xiaoxia, Chia, Sook Yoong, Varnäs, Katarina, Jiang, Mei, Zhang, Ke, Saw, Wuan Ting, Padmanabhan, Parasuraman, Yu, Wei-Ping, Zhou, Zhi-Dong, Halldin, Christer, Gulyás, Balázs, Tan, Eng-King, Zeng, Li

“…Abstract Vacuolar protein sorting 35 (VPS35) is a major component of the retromer complex that mediates the retrograde transport of cargo proteins from…”
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RNA Binding Protein Ybx2 Regulates RNA Stability During Cold-Induced Brown Fat Activation by Xu, Dan, Xu, Shaohai, Kyaw, Aung Maung Maung, Lim, Yen Ching, Chia, Sook Yoong, Chee Siang, Diana Teh, Alvarez-Dominguez, Juan R, Chen, Peng, Leow, Melvin Khee-Shing, Sun, Lei

“…Recent years have seen an upsurge of interest in brown adipose tissue (BAT) to combat the epidemic of obesity and diabetes. How its development and activation…”
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HOXC10 suppresses browning of white adipose tissues by Ng, Yvonne, Tan, Shi-Xiong, Chia, Sook Yoong, Tan, Hwee Yim Angeline, Gun, Sin Yee, Sun, Lei, Hong, Wanjin, Han, Weiping

“…Given that increased thermogenesis in white adipose tissue, also known as browning, promotes energy expenditure, significant efforts have been invested to…”
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HOXC10 suppresses browning of white adipose tissues by Yvonne Ng, Shi-Xiong Tan, Sook Yoong Chia, Hwee Yim Angeline Tan(Technology and Research, Sin Yee Gun(Technology and Research, Lei Sun(Technology and Research, Wanjin Hong(Technology and Research, Weiping Han(Technology and Research

“…Given that increased thermogenesis in white adipose tissue, also known as browning, promotes energy expenditure, significant efforts have been invested to…”
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