Search Results - "Chia, K. S."

Severity of CIND and MCI predict incidence of dementia in an ischemic stroke cohort by NARASIMHALU, K, ANG, S, DE SILVA, D. A, WONG, M.-C, CHANG, H.-M, CHIA, K.-S, AUCHUS, A. P, CHEN, C

“…The utility of poststroke cognitive status, namely dementia, cognitive impairment no dementia (CIND), mild cognitive impairment (MCI), and no cognitive…”
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Impact of sequence order of anthracyclines and taxanes in neoadjuvant chemotherapy on pathologic complete response rate in HER2-negative breast cancer patients by Tesch, M. E., Chia, S. K., Simmons, C. E., LeVasseur, N.

“…Purpose Data exploring optimal sequencing of anthracyclines and taxanes as neoadjuvant chemotherapy (NACT) for breast cancer are limited and inconsistent. The…”
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Concordance among gene expression-based predictors for ER-positive breast cancer treated with adjuvant tamoxifen by Prat, A., Parker, J.S., Fan, C., Cheang, M.C.U., Miller, L.D., Bergh, J., Chia, S.K.L., Bernard, P.S., Nielsen, T.O., Ellis, M.J., Carey, L.A., Perou, C.M.

“…ER-positive (ER+ ) breast cancer includes all of the intrinsic molecular subtypes, although the luminal A and B subtypes predominate. In this study, we…”
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A prospective clinical utility and pharmacoeconomic study of the impact of the 21-gene Recurrence Score® assay in oestrogen receptor positive node negative breast cancer by Davidson, J.A, Cromwell, I, Ellard, S.L, Lohrisch, C, Gelmon, K.A, Shenkier, T, Villa, D, Lim, H, Sun, S, Taylor, S, Taylor, M, Czerkawski, B, Hayes, M, Ionescu, D.N, Yoshizawa, C, Chao, C, Peacock, S, Chia, S.K

“…Abstract Purpose The primary purpose of this study was to measure the impact of the 21-gene Recurrence Score® result on systemic treatment recommendations and…”
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Mammographic density and its interaction with other breast cancer risk factors in an Asian population by Wong, C S, Lim, G H, Gao, F, Jakes, R W, Offman, J, Chia, K S, Duffy, S W

“…Background: Joint effects of mammographic density and other risk factors on breast cancer risk remain unclear. Methods: From The Singapore Breast Screening…”
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Production of methanol from biomass waste via pyrolysis by Kamarudin, S.K., Shamsul, N.S., Ghani, J.A., Chia, S.K., Liew, H.S., Samsudin, A.S.

“…► Production of methanol and ethanol from agricultural, forestry and animal waste. ► Sugarcane bagasse shows the highest potential for methanol production. ►…”
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Parental perspectives towards sugar-sweetened beverages and polices: a qualitative study by Chan, J. X. Y., Wong, M. L., Gao, X., Chia, K. S., Hong, C. H. L., Hu, S.

“…Purpose This qualitative study aimed to understand parental perception of (1) sugar-sweetened beverages (SSB) and implications of SSB on health; (2) their role…”
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Quantifying the natural history of breast cancer by Tan, K H X, Simonella, L, Wee, H L, Roellin, A, Lim, Y-W, Lim, W-Y, Chia, K S, Hartman, M, Cook, A R

“…Background: Natural history models of breast cancer progression provide an opportunity to evaluate and identify optimal screening scenarios. This paper…”
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Angiotensin-I converting enzyme insertion/deletion polymorphism and its association with diabetic nephropathy : a meta-analysis of studies reported between 1994 and 2004 and comprising 14,727 subjects by NG, D. P. K, TAI, B. C, KOH, D, TAN, K. W, CHIA, K. S

“…The ACE insertion/deletion polymorphism has been examined for association with diabetic nephropathy over the past decade with conflicting results. To clarify…”
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Basal cell carcinoma, squamous cell carcinoma and melanoma of the skin: analysis of the Singapore Cancer Registry data 1968-97 by Koh, D., Wang, H., Lee, J., Chia, K.S., Lee, H.P., Goh, C.L.

“…Summary Background There has been an alarming recent increase in skin cancer incidence among fair‐skinned populations. Information from Asian populations is…”
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Ethnic differences in acute myocardial infarction in Singapore by Mak, K.-H., Chia, K.-S., Kark, J.D., Chua, T., Tan, C., Foong, B.-H., Lim, Y.-L., Chew, S.-K.

“…Aims We compare the myocardial infarction (MI) event and mortality rates among Chinese, Malay and Indian residents of Singapore. Methods Residents, aged 20 to…”
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Translational aspects of genetic factors in the prediction of drug response variability: a case study of warfarin pharmacogenomics in a multi-ethnic cohort from Asia by Chan, S L, Suo, C, Lee, S C, Goh, B C, Chia, K S, Teo, Y Y

“…Genetic markers displaying highly significant statistical associations with complex phenotypes may not necessarily possess sufficient clinical validity to be…”
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Carbonic anhydrase XII is a marker of good prognosis in invasive breast carcinoma by WATSON, P. H, CHIA, S. K, WYKOFF, C. C, HAN, C, LEEK, R. D, SLY, W. S, GATTER, K. C, RATCLIFFE, P, HARRIS, A. L

“…Hypoxia and pH influence gene expression in tumours, and it is becoming increasingly clear that the pattern of genes expressed by a tumour determines its…”
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Ethnicity modifies the association between diabetes mellitus and ischaemic heart disease in Chinese, Malays and Asian Indians living in Singapore by YEO, K. K, TAI, B. C, HENG, D, LEE, J. M. J, MA, S, HUGHES, K, CHEW, S. K, CHIA, K. S, TAI, E. S

“…The aim of the study was to determine whether the risk of ischaemic heart disease (IHD) associated with diabetes mellitus differs between ethnic groups…”
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LAG-3+ tumor infiltrating lymphocytes in breast cancer: clinical correlates and association with PD-1/PD-L1+ tumors by Burugu, S., Gao, D., Leung, S., Chia, S.K., Nielsen, T.O.

“…Novel immune checkpoint blockade strategies are being evaluated in clinical trials and include targeting the lymphocyte activation gene 3 (LAG-3) checkpoint,…”
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Second primary malignancies in patients with male breast cancer by HEMMINKI, K, SCELO, G, CHIA, K.-S, POMPE-KIRN, V, MARTOS, C, JONASSON, J. G, LI, X, BRENNAN, P, BOFFETTA, P, MELLEMKJAER, L, TRACEY, E, ANDERSEN, A, BREWSTER, D. H, PUKKALA, E, MCBRIDE, M, KLIEWER, E. V

“…An international multicentre study of first and second primary neoplasms associated with male breast cancer was carried out by pooling data from 13 cancer…”
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Effect of childbirth after treatment on long-term survival from breast cancer by Verkooijen, H. M., Lim, G. H., Czene, K., Bhalla, V., Chow, K. Y., Yap, K. P. L., Chia, K. S., Hartman, M.

“…Background: This study quantified long‐term absolute and relative mortality risks of survivors of breast cancer with subsequent childbirth. Methods: The…”
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Risks of second primary cancer among patients with major histological types of lung cancers in both men and women by Chuang, S-C, Scélo, G, Lee, Y-C A, Friis, S, Pukkala, E, Brewster, D H, Hemminki, K, Tracey, E, Weiderpass, E, Tamaro, S, Pompe-Kirn, V, Kliewer, E V, Chia, K-S, Tonita, J M, Martos, C, Jonasson, J G, Boffetta, P, Brennan, P, Hashibe, M

“…Background: Patterns of second primary cancers (SPCs) following first primary lung cancers (FPLCs) may provide aetiological insights into FPLC. Methods: Cases…”
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Prognostic Significance of a Novel Hypoxia-Regulated Marker, Carbonic Anhydrase IX, in Invasive Breast Carcinoma by CHIA, Stephen K, WYKOFF, Charles C, WATSON, Peter H, CHENG HAN, LEEK, Russell D, PASTOREK, Jaromir, GATTER, Kevin C, RATCLIFFE, Peter, HARRIS, Adrian L

“…To assess the frequency of expression and the prognostic significance of a hypoxia-regulated marker, carbonic anhydrase IX (CA IX), in a cohort of patients…”
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Late risk of relapse and mortality among postmenopausal women with estrogen responsive early breast cancer after 5 years of tamoxifen by Kennecke, H.F., Olivotto, I.A., Speers, C., Norris, B., Chia, S.K., Bryce, C., Gelmon, K.A.

“…Background: Letrozole after 5 years of adjuvant tamoxifen results in a significant reduction in risk of recurrence from estrogen receptor (ER) positive breast…”
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