Search Results - "Chi, Menghui"
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Plumbagin inhibits fungal growth, HMGB1/LOX-1 pathway and inflammatory factors in A. fumigatus keratitis
Published in Frontiers in microbiology (09-04-2024)“…To investigate the anti-inflammatory and antifungal effects of plumbagin (PL) in ( ) keratitis, the minimum inhibitory concentration (MIC), time-killing curve,…”
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Benzyl isothiocyanate improves the prognosis of Aspergillus fumigatus keratitis by reducing fungal load and inhibiting Mincle signal pathway
Published in Frontiers in microbiology (16-02-2023)“…keratitis is a potential blinding disease associated with invasion and excessive inflammatory response. Benzyl isothiocyanate (BITC) is a secondary metabolite…”
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Mesoporous zinc oxide-based drug delivery system offers an antifungal and immunoregulatory strategy for treating keratitis
Published in Journal of controlled release (01-04-2024)“…Fungal keratitis is a refractory eye disease that is prone to causing blindness. Fungal virulence and inflammatory responses are two major factors that…”
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Pentoxifylline treats Aspergillus fumigatus keratitis by reducing fungal burden and suppressing corneal inflammation
Published in European journal of pharmacology (15-04-2023)“…Fungal keratitis (FK) is a blinding ocular disease, which mainly results from fungal damage and excessive inflammation. Pentoxifylline, a kind of…”
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Chelerythrine ameliorates Aspergillus fumigatus keratitis through suppressing the LOX-1/p38 MAPK signaling pathway
Published in Cytokine (Philadelphia, Pa.) (01-10-2024)“…•Chelerythrine treatment reduced the severity of fungal keratitis in mice.•Chelerythrine exhibited anti-fungal activity against A. fumigatus both in vivo and…”
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Resveratrol has neuroprotective effects and plays an anti-inflammatory role through Dectin-1/p38 pathway in Aspergillus fumigatus keratitis
Published in Cytokine (Philadelphia, Pa.) (01-07-2024)“…•Resveratrol exertsantifungal activitiesagainst Aspergillus fumigatus (A. fumigatus)•Resveratrol alleviates the severity of mouse fungal keratitis.•Resveratrol…”
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Oxymatrine mitigates Aspergillus fumigatus keratitis by suppressing fungal activity and restricting pyroptosis
Published in Experimental eye research (01-03-2024)“…Fungal keratitis (FK) is a refractory keratitis caused by excessive inflammation and fungal damage. Excessive inflammation can lead to tissue damage and…”
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The therapeutic role and mechanism of 4-Methoxycinnamic acid in fungal keratitis
Published in International immunopharmacology (01-03-2023)“…•MCA exerts antifungal effects by inhibiting fungal cell wall synthesis, disrupting cell membrane permeability, and inhibiting biofilm formation.•The…”
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Zeolitic Imidazolate Framework-8 Offers an Anti-Inflammatory and Antifungal Method in the Treatment of Aspergillus Fungal Keratitis in vitro and in vivo
Published in International journal of nanomedicine (01-11-2024)“…Fungal keratitis is a serious blinding eye disease. Traditional drugs used to treat fungal keratitis commonly have the disadvantages of low bioavailability,…”
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ZIF-90 treats fungal keratitis by promoting macrophage apoptosis and inhibiting inflammatory response
Published 27-10-2024“…Fungal keratitis is a severe vision-threatening corneal infection with a prognosis influenced by fungal virulence and the host's immune defense mechanisms. The…”
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Zeolitic Imidazolate Framework-8 offers an anti-inflammatory and antifungal method in the treatment of Aspergillus fungus keratitis in vitro and in vivo
Published 29-09-2024“…Background: Fungal keratitis is a serious blinding eye disease. Traditional drugs used to treat fungal keratitis commonly have the disadvantages of low…”
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