Search Results - "Chi, Jufang"

Dihydromyricetin Prevents Diabetic Cardiomyopathy via miR-34a Suppression by Activating Autophagy by Ni, Tingjuan, Lin, Na, Lu, Wenqiang, Sun, Zhenzhu, Lin, Hui, Chi, Jufang, Guo, Hangyuan

“…Purpose The pro-aging miRNA, miR-34a, is hyperactivated in the cardiac myocardial tissues of patients and mice with diabetes, leading to diabetic…”
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Dark chocolate intake and cardiovascular diseases: a Mendelian randomization study by Yang, Juntao, Zhou, Jiedong, Yang, Jie, Lou, Haifei, Zhao, Bingjie, Chi, Jufang, Tang, Weiliang

“…Previous intervention studies have shown some benefits of dark chocolate for the cardiovascular system, but it has not been established whether dark chocolate…”
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LncRNA GHET1 from bone mesenchymal stem cell–derived exosomes improves doxorubicin-induced pyroptosis of cardiomyocytes by mediating NLRP3 by Zhai, Xiaoya, Zhou, Jiedong, Huang, Xingxiao, Weng, Jingfan, Lin, Hui, Sun, Shimin, Chi, Jufang, Meng, Liping

“…Doxorubicin (DOX) is an important chemotherapeutic agent for the treatment of hematologic tumors and breast carcinoma. However, its clinical application is…”
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Protective effect of urotensin II receptor antagonist urantide and exercise training on doxorubicin-induced cardiotoxicity by Sun, Jing, Zhou, Jiedong, Sun, Shimin, Lin, Hui, Zhang, Hanlin, Zhong, Zuoquan, Chi, Jufang, Guo, HangYuan

“…Doxorubicin (DOX) has a wide antitumor spectrum, but its adverse cardiotoxicity may lead to heart failure. Urotensin II (UII) is the most potent…”
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Inhibiting mir-34a-5p regulates doxorubicin-induced autophagy disorder and alleviates myocardial pyroptosis by targeting Sirt3-AMPK pathway by Zhong, Zuoquan, Gao, Yefei, Zhou, Jiedong, Wang, Fang, Zhang, Peipei, Hu, Songqing, Wu, Haowei, Lou, Haifei, Chi, Jufang, Lin, Hui, Guo, Hangyuan

“…Doxorubicin (DOX) is a commonly used chemotherapy drug widely applied in various cancers such as breast cancer, leukemia, and sarcomas. However, its usage is…”
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Icariin Ameliorates Diabetic Cardiomyopathy Through Apelin/Sirt3 Signalling to Improve Mitochondrial Dysfunction by Ni, Tingjuan, Lin, Na, Huang, Xingxiao, Lu, Wenqiang, Sun, Zhenzhu, Zhang, Jie, Lin, Hui, Chi, Jufang, Guo, Hangyuan

“…Myocardial contractile dysfunction in diabetic cardiomyocytes is a significant promoter of heart failure. Herein, we investigated the effect of icariin, a…”
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Fucoidan from Fucus vesiculosus attenuates doxorubicin-induced acute cardiotoxicity by regulating JAK2/STAT3-mediated apoptosis and autophagy by Zhang, Jie, Sun, Zhenzhu, Lin, Na, Lu, Wenqiang, Huang, Xingxiao, Weng, Jingfan, Sun, Shimin, Zhang, Chuanjing, Yang, Qi, Zhou, Guozhong, Guo, Hangyuan, Chi, Jufang

“…•Doxorubicin induces acute cardiotoxicity accompanied by disordered apoptosis and autophagy in vivo and vitro.•Fucoidan could restore doxorubicin-induced acute…”
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A Nomogram for Predicting Patent Foramen Ovale-Related Stroke Recurrence by Wu, Zhuonan, Zhang, Chuanjing, Liu, Nan, Xie, Wenqing, Yang, Jinjin, Guo, Hangyuan, Chi, Jufang

“…Background The high prevalence of patent foramen ovale (PFO) in cryptogenic stroke suggested a stroke-causing role for PFO. As risk factors for recurrence of…”
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SGLT1 Inhibition Attenuates Apoptosis in Diabetic Cardiomyopathy via the JNK and p38 Pathway by Lin, Na, Lin, Hui, Yang, Qi, Lu, Wenqiang, Sun, Zhenzhu, Sun, Shimin, Meng, Liping, Chi, Jufang, Guo, Hangyuan

“…Recent studies have revealed that a novel selective sodium-glucose cotransporter 1 (SGLT1) inhibiton has shown beneficial effects in cardiovascular diseases…”
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Yellow Wine Polyphenolic Compounds Inhibit Matrix Metalloproteinase-2, -9 Expression and Improve Atherosclerotic Plaque in LDL-Receptor–Knockout Mice by Zhai, Xiaoya, Chi, Jufang, Tang, Weiliang, Ji, Zheng, Zhao, Fei, Jiang, Chengjian, Lv, Haitao, Guo, Hangyuan

“…Many epidemiological studies have strongly suggested an inverse correlation between dietary polyphenol consumption and reduced risks of cardiovascular…”
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Herpud1 deficiency could reduce amyloid-β40 expression and thereby suppress homocysteine-induced atherosclerosis by blocking the JNK/AP1 pathway by Gao, Feidan, Zhang, Jie, Ni, Tingjuan, Lin, Na, Lin, Hui, Luo, Hangqi, Guo, Hangyuan, Chi, Jufang

“…Homocysteine (Hcy) is considered an independent risk factor for various cardiovascular diseases including atherosclerosis which is associated with lipid…”
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Functional components of Chinese rice wine can ameliorate diabetic cardiomyopathy through the modulation of autophagy, apoptosis, gut microbiota, and metabolites by Yang, Jinjin, Song, Jiaoying, Zhou, Jiedong, Lin, Hui, Wu, Zhuonan, Liu, Nan, Xie, Wenqing, Guo, Hangyuan, Chi, Jufang

“…Background Dietary polyphenols, polypeptides, and oligosaccharides modulate inflammation and immunity by altering the composition of gut microbiota. The…”
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The effect of ivabradine therapy on dilated cardiomyopathy patients with congestive heart failure: a systematic review and meta-analysis by Yang, Juntao, Lv, Tingting, Zhou, Jiedong, Lin, Hui, Zhao, Bingjie, Lou, Haifei, Liu, Hanxuan, Zhang, Tao, Guo, Hangyuan, Chi, Jufang

“…Background Ivabradine improves cardiac function in patients with heart failure, but its effect on dilated cardiomyopathy (DCM) remains unclear. We performed a…”
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Inappropriate Activation of TLR4/NF-κB is a Cause of Heart Failure by Zhou, Jiedong, Lin, Hui, Lv, Tingting, Hao, Jinjin, Zhang, Hanlin, Sun, Shimin, Yang, Juntao, Chi, Jufang, Guo, Hangyuan

“…Significance: Heart failure, a disease with extremely high incidence, is closely associated with inflammation and oxidative stress. The Toll-like receptor 4…”
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Repair effect of the poly (D,L-lactic acid) nanoparticle containing tauroursodeoxycholic acid-eluting stents on endothelial injury after stent implantation by Zhou, Jiedong, Weng, Jingfan, Huang, Xingxiao, Sun, Shimin, Yang, Qi, Lin, Hui, Yang, Jinjin, Guo, Hangyuan, Chi, Jufang

“…Background Chronic endoplasmic reticulum stress (ERS) plays a crucial role in cardiovascular diseases. Thus, it can be considered a therapeutic target for…”
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Machine learning algorithms identifying the risk of new-onset ACS in patients with type 2 diabetes mellitus: A retrospective cohort study by Zhong, Zuoquan, Sun, Shiming, Weng, Jingfan, Zhang, Hanlin, Lin, Hui, Sun, Jing, Pan, Miaohong, Guo, Hangyuan, Chi, Jufang

“…In recent years, the prevalence of type 2 diabetes mellitus (T2DM) has increased annually. The major complication of T2DM is cardiovascular disease (CVD). CVD…”
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Effects of Chinese yellow wine on nitric oxide synthase and intercellular adhesion molecule-1 expressions in rat vascular endothelial cells by Zhao, Fei, Ji, Zheng, Chi, Jufang, Tang, Weiliang, Zhai, Xiaoya, Meng, Liping, Guo, Hangyuan

“…Objective The objective of this study was to determine similarities in the effect of yellow wine as compared to statin and the possibility that yellow wine…”
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Rosuvastatin Inhibits MMP-2 Expression and Limits the Progression of Atherosclerosis in LDLR-deficient Mice by Guo, Hangyuan, Shi, Yafei, Liu, Longbin, Sun, Aijing, Xu, Fukang, Chi, Jufang

“…Background and Aims Statins have been shown to reduce morbidity and mortality of coronary heart disease (CHD). Matrix metalloproteinases (MMPs) have been found…”
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Chinese yellow wine and red wine inhibit matrix metalloproteinase-2 and improve atherosclerotic plaque in LDL receptor knockout mice by Guo, Hangyuan, Liu, Longbin, Shi, Yafei, Sun, Aijing, Xu, Fukang, Chi, Jufang, Huang, Dilai

“…Our previous study found that Chinese yellow wine could inhibit the production of homocysteine (HCY) induced extracellular matrix metalloproteinase-2 (MMP-2)…”
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Rosuvastatin may Modulate Insulin Signaling and Inhibit Atherogenesis Beyond its Plasma Cholesterol-Lowering Effect in Insulin-Resistant Mice by Guo, Hangyuan, Lv, Haitao, Tang, Weiliang, Chi, Jufang, Liu, Longbin, Xu, Fukang, Ji, Zheng, Zhai, Xiaoya, Peng, Fang

“…Objectives To provide evidence that rosuvastatin may improve insulin-resistance and inhibit atherogenesis by modulating insulin signaling, and whether this…”
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