Search Results - "Chi, Alicia"

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  1. 1

    Human Endometrial Transcriptome and Progesterone Receptor Cistrome Reveal Important Pathways and Epithelial Regulators by Chi, Ru-pin Alicia, Wang, Tianyuan, Adams, Nyssa, Wu, San-pin, Young, Steven L, Spencer, Thomas E, DeMayo, Francesco

    “…Abstract Context Poor uterine receptivity is one major factor leading to pregnancy loss and infertility. Understanding the molecular events governing…”
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    Journal Article
  2. 2

    Inhibition of Kpnβ1 mediated nuclear import enhances cisplatin chemosensitivity in cervical cancer by Chi, Ru-Pin Alicia, van der Watt, Pauline, Wei, Wei, Birrer, Michael J, Leaner, Virna D

    Published in BMC cancer (02-02-2021)
    “…Inhibition of nuclear import via Karyopherin beta 1 (Kpnβ1) shows potential as an anti-cancer approach. This study investigated the use of nuclear import…”
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    Journal Article
  3. 3

    Targeting nuclear transporters in cancer: Diagnostic, prognostic and therapeutic potential by Stelma, Tamara, Chi, Alicia, van der Watt, Pauline J., Verrico, Annalisa, Lavia, Patrizia, Leaner, Virna D.

    Published in IUBMB life (01-04-2016)
    “…The Karyopherin superfamily is a major class of soluble transport receptors consisting of both import and export proteins. The trafficking of proteins involved…”
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  4. 4

    Targeting the Nuclear Import Receptor Kpnβ1 as an Anticancer Therapeutic by van der Watt, Pauline J, Chi, Alicia, Stelma, Tamara, Stowell, Catherine, Strydom, Erin, Carden, Sarah, Angus, Liselotte, Hadley, Kate, Lang, Dirk, Wei, Wei, Birrer, Michael J, Trent, John O, Leaner, Virna D

    Published in Molecular cancer therapeutics (01-04-2016)
    “…Karyopherin beta 1 (Kpnβ1) is a nuclear transport receptor that imports cargoes into the nucleus. Recently, elevated Kpnβ1 expression was found in certain…”
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    Journal Article
  5. 5

    A tight balance of Karyopherin β1 expression is required in cervical cancer cells by Carden, Sarah, van der Watt, Pauline, Chi, Alicia, Ajayi-Smith, Aderonke, Hadley, Katie, Leaner, Virna D

    Published in BMC cancer (16-11-2018)
    “…Karyopherin β1 (Kpnβ1) is the main nuclear import protein involved in the transport of cargoes from the cytoplasm into the cell nucleus. Previous research has…”
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    Journal Article
  6. 6

    WNK1 regulates uterine homeostasis and its ability to support pregnancy by Chi, Ru-Pin Alicia, Wang, Tianyuan, Huang, Chou-Long, Wu, San-Pin, Young, Steven L, Lydon, John P, DeMayo, Francesco J

    Published in JCI insight (19-11-2020)
    “…WNK1 (with no lysine [K] kinase 1) is an atypical kinase protein ubiquitously expressed in humans and mice. A mutation in its encoding gene causes hypertension…”
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  7. 7

    A unique poly(A) tail profile uncovers the stability and translational activation of TOP transcripts during neuronal differentiation by Baptissart, Marine, Papas, Brian N., Chi, Ru-pin Alicia, Li, Yin, Lee, Dongwon, Puviindran, Bhairavy, Morgan, Marcos

    Published in iScience (15-09-2023)
    “…Cell differentiation is associated with global changes in translational activity. Here, we characterize how mRNA poly(A) tail processing supports this dynamic…”
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  8. 8

    WNK1 is required during male pachynema to sustain fertility by Chi, Ru-pin Alicia, Xu, Xiaojiang, Li, Jian-Liang, Xu, Xin, Hu, Guang, Brown, Paula, Willson, Cynthia, Kirsanov, Oleksandr, Geyer, Christopher, Huang, Chou-Long, Morgan, Marcos, DeMayo, Francesco

    Published in iScience (15-09-2023)
    “…WNK1 is an important regulator in many physiological functions, yet its role in male reproduction is unexplored. In the male germline, WNK1 is upregulated in…”
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  9. 9
  10. 10

    Abstract B09: KPNB1-mediated nuclear import is required for inflammatory cytokine expression, invasion and survival of cancer cells by Stelma, Tamara, Chi, Alicia, Mall, Anwar, Govender, Dhiren, Leaner, Virna D.

    Published in Cancer research (Chicago, Ill.) (15-11-2017)
    “…Abstract Karyopherin β1 (KPNB1) is a nuclear transport protein involved in the transport of transcription factors and other proteins containing a nuclear…”
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    Journal Article
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  14. 14

    Inhibition of Kpn[beta]1 mediated nuclear import enhances cisplatin chemosensitivity in cervical cancer by Chi, Ru-pin Alicia, van der Watt, Pauline, Wei, Wei, Birrer, Michael J, Leaner, Virna D

    Published in BMC cancer (02-02-2021)
    “…Background Inhibition of nuclear import via Karyopherin beta 1 (Kpn[beta]1) shows potential as an anti-cancer approach. This study investigated the use of…”
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    Journal Article