Search Results - "Chi, Alicia"
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Human Endometrial Transcriptome and Progesterone Receptor Cistrome Reveal Important Pathways and Epithelial Regulators
Published in The journal of clinical endocrinology and metabolism (01-04-2020)“…Abstract Context Poor uterine receptivity is one major factor leading to pregnancy loss and infertility. Understanding the molecular events governing…”
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Inhibition of Kpnβ1 mediated nuclear import enhances cisplatin chemosensitivity in cervical cancer
Published in BMC cancer (02-02-2021)“…Inhibition of nuclear import via Karyopherin beta 1 (Kpnβ1) shows potential as an anti-cancer approach. This study investigated the use of nuclear import…”
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Targeting nuclear transporters in cancer: Diagnostic, prognostic and therapeutic potential
Published in IUBMB life (01-04-2016)“…The Karyopherin superfamily is a major class of soluble transport receptors consisting of both import and export proteins. The trafficking of proteins involved…”
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Targeting the Nuclear Import Receptor Kpnβ1 as an Anticancer Therapeutic
Published in Molecular cancer therapeutics (01-04-2016)“…Karyopherin beta 1 (Kpnβ1) is a nuclear transport receptor that imports cargoes into the nucleus. Recently, elevated Kpnβ1 expression was found in certain…”
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A tight balance of Karyopherin β1 expression is required in cervical cancer cells
Published in BMC cancer (16-11-2018)“…Karyopherin β1 (Kpnβ1) is the main nuclear import protein involved in the transport of cargoes from the cytoplasm into the cell nucleus. Previous research has…”
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WNK1 regulates uterine homeostasis and its ability to support pregnancy
Published in JCI insight (19-11-2020)“…WNK1 (with no lysine [K] kinase 1) is an atypical kinase protein ubiquitously expressed in humans and mice. A mutation in its encoding gene causes hypertension…”
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A unique poly(A) tail profile uncovers the stability and translational activation of TOP transcripts during neuronal differentiation
Published in iScience (15-09-2023)“…Cell differentiation is associated with global changes in translational activity. Here, we characterize how mRNA poly(A) tail processing supports this dynamic…”
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WNK1 is required during male pachynema to sustain fertility
Published in iScience (15-09-2023)“…WNK1 is an important regulator in many physiological functions, yet its role in male reproduction is unexplored. In the male germline, WNK1 is upregulated in…”
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Prevalence of Haematoloechus pulcher metacercariae (Digenea: Plagiorchioidea) in the crayfish Cambarellus montezumae in Salazar Lagoon, Estado de México
Published in Revista mexicana de biodiversidad (01-09-2015)“…Crayfish can be intermediate hosts of larval digeneans. Cambarellus montezumae is a crustacean endemic of the Mexican plateau and is part of the diet of the…”
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Abstract B09: KPNB1-mediated nuclear import is required for inflammatory cytokine expression, invasion and survival of cancer cells
Published in Cancer research (Chicago, Ill.) (15-11-2017)“…Abstract Karyopherin β1 (KPNB1) is a nuclear transport protein involved in the transport of transcription factors and other proteins containing a nuclear…”
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Targeting nuclear transporters in cancer: Diagnostic, prognostic and therapeutic potential: TARGETING NUCLEAR TRANSPORTERS IN CANCER
Published in IUBMB life (01-04-2016)Get full text
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Inhibition of Kpn[beta]1 mediated nuclear import enhances cisplatin chemosensitivity in cervical cancer
Published in BMC cancer (02-02-2021)“…Background Inhibition of nuclear import via Karyopherin beta 1 (Kpn[beta]1) shows potential as an anti-cancer approach. This study investigated the use of…”
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Journal Article