Search Results - "Chhibbar, Prabal"

From bench to bedside via bytes: Multi-omic immunoprofiling and integration using machine learning and network approaches by Xiao, Hanxi, Rosen, Aaron, Chhibbar, Prabal, Moise, Lenny, Das, Jishnu

“…A significant surge in research endeavors leverages the vast potential of high-throughput omic technology platforms for broad profiling of biological responses…”
Get full text

559: IMMUNE MICROENVIRONMENT PROFILING OF NORMAL APPEARING COLORECTAL TISSUES SEPARATES LYNCH SYNDROME PATIENTS ALONG THEIR COLON CANCER STATUS by Brand, Rhonda, Uttam, Shikhar, Zyhowski, Ashley, Pitlor, Danielle, Chhibbar, Prabal, Metter, E. Jeffrey, Dudley, Beth, Karloski, Eve, Brand, Randall

Get full text

Correlates of COVID-19 mRNA vaccine humoral immune responses in men living with HIV-1 by Tuttle, Dylan J., Castanha, Priscila M. S., Nasser, Amro, Wilkins, Maris S., Cuff, Deirdre E., Chhibbar, Prabal, Sluis-Cremer, Nicolas P., Das, Jishnu, Mailliard, Robbie B., Rinaldo, Charles R., Marques, Ernesto T. A.

“…It is important that people with HIV-1 (PWH) receive an FDA-approved vaccine for COVID-19. Because PWH are known to elicit less effective immune responses to…”
Get full text

Temporal dynamics and genomic programming of plasma cell fates by Manakkat Vijay, Godhev Kumar, Zhou, Ming, Thakkar, Kairavee, Rothrauff, Abigail, Chawla, Amanpreet Singh, Chen, Dianyu, Lau, Louis Chi-Wai, Gerges, Peter Habib, Chetal, Kashish, Chhibbar, Prabal, Fan, Jingyu, Das, Jishnu, Joglekar, Alok, Borghesi, Lisa, Salomonis, Nathan, Xu, Heping, Singh, Harinder

“…Affinity-matured plasma cells (PCs) of varying lifespans are generated through a germinal center (GC) response. The developmental dynamics and genomic programs…”
Get full text

Uncovering cell-type-specific immunomodulatory variants and molecular phenotypes in COVID-19 using structurally resolved protein networks by Chhibbar, Prabal, Guha Roy, Priyamvada, Harioudh, Munesh K., McGrail, Daniel J., Yang, Donghui, Singh, Harinder, Hinterleitner, Reinhard, Gong, Yi-Nan, Yi, S. Stephen, Sahni, Nidhi, Sarkar, Saumendra N., Das, Jishnu

“…Immunomodulatory variants that lead to the loss or gain of specific protein interactions often manifest only as organismal phenotypes in infectious disease…”
Get full text

SARS-CoV-2 mRNA Vaccines Induce Greater Complement Activation and Decreased Viremia and Nef Antibodies in Men With HIV-1 by Tuttle, Dylan J, Castanha, Priscila M S, Nasser, Amro, Wilkins, Maris S, Galarza, Tamara García, Alaoui-El-Azher, Mounia, Cuff, Deirdre E, Chhibbar, Prabal, Das, Jishnu, Li, Yijia, Barratt-Boyes, Simon M, Mailliard, Robbie B, Sluis-Cremer, Nicolas, Rinaldo, Charles R, Marques, Ernesto T A

“…Abstract Background Immune dysregulation in people with human immunodeficiency virus-1 (PWH) persists despite potent antiretroviral therapy and, consequently,…”
Get full text

Generating protein sequences from antibiotic resistance genes data using Generative Adversarial Networks by Chhibbar, Prabal, Joshi, Arpit

“…We introduce a method to generate synthetic protein sequences which are predicted to be resistant to certain antibiotics. We did this using 6,023 genes that…”
Get full text