Search Results - "Chhaya, Meha"

Off-target binding of an anti-amyloid beta monoclonal antibody to platelet factor 4 causes acute and chronic toxicity in cynomolgus monkeys by Loberg, Lise I, Chhaya, Meha, Ibraghimov, Alexander, Tarcsa, Edit, Striebinger, Andreas, Popp, Andreas, Huang, Lili, Oellien, Frank, Barghorn, Stefan

“…ABT-736 is a humanized monoclonal antibody generated to target a specific conformation of the amyloid-beta (Aβ) protein oligomer. Development of ABT-736 for…”
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Protein language models enable prediction of polyreactivity of monospecific, bispecific, and heavy-chain-only antibodies by Yu, Xin, Vangjeli, Kostika, Prakash, Anusha, Chhaya, Meha, Stanley, Samantha J, Cohen, Noah, Huang, Lili

“…Abstract Background Early assessment of antibody off-target binding is essential for mitigating developability risks such as fast clearance, reduced efficacy,…”
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Targeting Anti-TGF- β Therapy to Fibrotic Kidneys with a Dual Specificity Antibody Approach by McGaraughty, Steve, Davis-Taber, Rachel A, Zhu, Chang Z, Cole, Todd B, Nikkel, Arthur L, Chhaya, Meha, Doyle, Kelly J, Olson, Lauren M, Preston, Gregory M, Grinnell, Christine M, Salte, Katherine M, Giamis, Anthony M, Luo, Yanping, Sun, Victor, Goodearl, Andrew D, Gopalakrishnan, Murali, Lacy, Susan E

“…Targeted delivery of a therapeutic agent to a site of pathology to ameliorate disease while limiting exposure at undesired tissues is an aspirational treatment…”
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Off-target binding of an anti-amyloid beta monoclonal antibody to platelet factor 4 causes acute and chronic toxicity in cynomolgus monkeys by Loberg, Lise I., Chhaya, Meha, Ibraghimov, Alexander, Tarcsa, Edit, Striebinger, Andreas, Popp, Andreas, Huang, Lili, Oellien, Frank, Barghorn, Stefan

“…ABT-736 is a humanized monoclonal antibody generated to target a specific conformation of the amyloid-beta (Aβ) protein oligomer. Development of ABT-736 for…”
Get full text