Search Results - "Chhabra, Ravneet"
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Molecular and modular intricacies of precision oncology
Published in Frontiers in immunology (23-10-2024)“…Precision medicine is revolutionizing the world in combating different disease modalities, including cancer. The concept of personalized treatments is not new,…”
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Journal Article -
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Lysophosphatidic acid reverses Temsirolimus-induced changes in lipid droplets and mitochondrial networks in renal cancer cells
Published in PloS one (03-06-2020)“…Increased cytoplasmic lipid droplets (LDs) and elevated AKT/mTOR signaling are characteristics of clear cell renal cell carcinoma (ccRCC). Lysophosphatidic…”
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Journal Article -
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Global miRNA/proteomic analyses identify miRNAs at 14q32 and 3p21, which contribute to features of chronic iron-exposed fallopian tube epithelial cells
Published in Scientific reports (18-03-2021)“…Malignant transformation of fallopian tube secretory epithelial cells (FTSECs) is a key contributing event to the development of high-grade serous ovarian…”
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Journal Article -
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Links Between Iron and Lipids: Implications in Some Major Human Diseases
Published in Pharmaceuticals (Basel, Switzerland) (22-10-2018)“…Maintenance of iron homeostasis is critical to cellular health as both its excess and insufficiency are detrimental. Likewise, lipids, which are essential…”
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Iron Pathways and Iron Chelation Approaches in Viral, Microbial, and Fungal Infections
Published in Pharmaceuticals (Basel, Switzerland) (25-09-2020)“…Iron is an essential element required to support the health of organisms. This element is critical for regulating the activities of cellular enzymes including…”
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Journal Article -
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11 Humanized ICOS mice as a novel tool for predicting and monitoring T-cell-mediated immunotherapy response
Published in Journal for immunotherapy of cancer (01-11-2023)“…BackgroundThe clinical response rate to checkpoint inhibitors can vary due to disease heterogeneity and complex tumor escape mechanisms, necessitating a need…”
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Journal Article -
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Deregulated expression of the 14q32 miRNA cluster in clear cell renal cancer cells
Published in Frontiers in oncology (17-04-2023)“…Clear cell renal cell carcinomas (ccRCC) are characterized by arm-wide chromosomal alterations. Loss at 14q is associated with disease aggressiveness in ccRCC,…”
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Trigger factor assisted folding of the recombinant epoxide hydrolases identified from C. pelagibacter and S. nassauensis
Published in Protein expression and purification (01-12-2014)“…•In this study, two EH encoding genes cpeh (1143bp) and sneh (891bp) have been cloned.•The overexpressed His6-tagged CPEH formed inclusion bodies and SNEH…”
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Journal Article -
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Cellular and Molecular Alterations Associated with Ovarian and Renal Cancer Pathophysiology
Published 01-01-2021“…Elucidating molecular alterations underlying tumor development and chemoresistance are critical to expand our understanding of the disease pathophysiology…”
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Dissertation -
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