Search Results - "Cheyne, Lesley"
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1
Characterization of the Myocardial Inflammatory Response in Acute Stress-Induced (Takotsubo) Cardiomyopathy
Published in JACC. Basic to translational science (01-12-2018)“…Visual Abstract…”
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2
Comparison of intramyocellular lipid metabolism in patients with diabetes and male athletes
Published in Nature communications (15-05-2024)“…Despite opposing insulin sensitivity and cardiometabolic risk, both athletes and patients with type 2 diabetes have increased skeletal myocyte fat storage: the…”
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3
Renin-Angiotensin and Endothelin Systems in Patients Post-Takotsubo Cardiomyopathy
Published in Journal of the American Heart Association (19-07-2022)“…Background We investigate if renin-angiotensin and endothelin-1 response pathways follow the same pattern of recovery as left ventricular ejection fraction in…”
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4
Synthesis and hyperpolarisation of eNOS substrates for quantification of NO production by 1H NMR spectroscopy
Published in Bioorganic & medicinal chemistry (15-05-2017)“…[Display omitted] Hyperpolarization enhances the intensity of the NMR signals of a molecule, whose in vivo metabolic fate can be monitored by MRI with higher…”
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5
Metabolic alterations in a rat model of takotsubo syndrome
Published in Cardiovascular research (29-06-2022)“…Abstract Aims Cardiac energetic impairment is a major finding in takotsubo patients. We investigate specific metabolic adaptations to direct future therapies…”
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6
Matrix-dependent size modifications of iron oxide nanoparticles (Ferumoxytol) spiked into rat blood cells and plasma: Characterisation with TEM, AF4-UV-MALS-ICP-MS/MS and spICP-MS
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15-08-2019)“…Engineered nanoparticles such as iron oxide (Fe3O4) nanoparticles (IONPs) offer several benefits in nanomedicine, notably as contrast agents in magnetic…”
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Parvalbumin-positive CA1 interneurons are required for spatial working but not for reference memory
Published in Nature neuroscience (01-03-2011)“…Parvalbumin-positive GABAergic interneurons in cortical circuits are hypothesized to control cognitive function. To test this idea directly, we functionally…”
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Abstract 10408: Insulin Resistance in Type 2 Diabetes is Moderated by Saturated Fatty Acids
Published in Circulation (New York, N.Y.) (08-11-2022)“…BackgroundIncreased intramyocellular lipid storage occurs in skeletal muscle of both athletes and type 2 diabetes patients (T2D) but their metabolic phenotypes…”
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Impaired Cardiac and Skeletal Muscle Energetics Following Anthracycline Therapy for Breast Cancer
Published in Circulation. Cardiovascular imaging (01-10-2023)“…BACKGROUNDAnthracycline-related cardiac toxicity is a recognized consequence of cancer therapies. We assess resting cardiac and skeletal muscle energetics and…”
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10
Fast field-cycling magnetic resonance detection of intracellular ultra-small iron oxide particles in vitro: Proof-of-concept
Published in Journal of magnetic resonance (1997) (01-04-2020)“…[Display omitted] •FFC-MR can detect and quantify dependence of macrophage USPIO R1 dispersion in vitro.•Inflammation assessment in vivo and the utility of…”
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11
Synthesis and hyperpolarisation of eNOS substrates for quantification of NO production by 1 H NMR spectroscopy
Published in Bioorganic & medicinal chemistry (15-05-2017)“…Hyperpolarization enhances the intensity of the NMR signals of a molecule, whose in vivo metabolic fate can be monitored by MRI with higher sensitivity. SABRE…”
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