Search Results - "Cheyne, Juliette E"
-
1
Spontaneous Activity Drives Local Synaptic Plasticity In Vivo
Published in Neuron (Cambridge, Mass.) (15-07-2015)“…Spontaneous activity fine-tunes neuronal connections in the developing brain. To explore the underlying synaptic plasticity mechanisms, we monitored naturally…”
Get full text
Journal Article -
2
Hippocampal Deficits in Amyloid-β-Related Rodent Models of Alzheimer's Disease
Published in Frontiers in neuroscience (07-04-2020)“…Alzheimer's disease (AD) is a progressive neurodegenerative disease that is the most common cause of dementia. Symptoms of AD include memory loss,…”
Get full text
Journal Article -
3
The Role of Zinc and NMDA Receptors in Autism Spectrum Disorders
Published in Pharmaceuticals (Basel, Switzerland) (20-12-2022)“…NMDA-type glutamate receptors are critical for synaptic plasticity in the central nervous system. Their unique properties and age-dependent arrangement of…”
Get full text
Journal Article -
4
Shankopathies in the Developing Brain in Autism Spectrum Disorders
Published in Frontiers in neuroscience (22-12-2021)“…The SHANK family of proteins play critical structural and functional roles in the postsynaptic density (PSD) at excitatory glutamatergic synapses. Through…”
Get full text
Journal Article -
5
Autism-associated mutations in ProSAP2/Shank3 impair synaptic transmission and neurexin-neuroligin-mediated transsynaptic signaling
Published in The Journal of neuroscience (24-10-2012)“…Mutations in several postsynaptic proteins have recently been implicated in the molecular pathogenesis of autism and autism spectrum disorders (ASDs),…”
Get full text
Journal Article -
6
4D super-resolution microscopy with conventional fluorophores and single wavelength excitation in optically thick cells and tissues
Published in PloS one (31-05-2011)“…Optical super-resolution imaging of fluorescently stained biological samples is rapidly becoming an important tool to investigate protein distribution at the…”
Get full text
Journal Article -
7
Spontaneous Activity Patterns Are Altered in the Developing Visual Cortex of the Fmr1 Knockout Mouse
Published in Frontiers in neural circuits (26-09-2019)“…Fragile X syndrome (FXS) is the most prevalent inherited cause of autism and is accompanied by behavioral and sensory deficits. Errors in the wiring of the…”
Get full text
Journal Article -
8
Auditory processing in rodent models of autism: a systematic review
Published in Journal of neurodevelopmental disorders (30-08-2022)“…Autism is a complex condition with many traits, including differences in auditory sensitivity. Studies in human autism are plagued by the difficulty of…”
Get full text
Journal Article -
9
Recording plasticity in neuronal activity in the rodent intrinsic cardiac nervous system using calcium imaging techniques
Published in Frontiers in synaptic neuroscience (04-04-2023)“…The intrinsic cardiac nervous system (ICNS) is composed of interconnected clusters of neurons called ganglionated plexi (GP) which play a major role in…”
Get full text
Journal Article -
10
Synaptic SAP97 Isoforms Regulate AMPA Receptor Dynamics and Access to Presynaptic Glutamate
Published in The Journal of neuroscience (08-04-2009)“…The synaptic insertion of GluR1-containing AMPA-type glutamate receptors (AMPARs) is critical for synaptic plasticity. However, mechanisms responsible for…”
Get full text
Journal Article -
11
Synaptic integration of newly generated neurons in rat dissociated hippocampal cultures
Published in Molecular and cellular neuroscience (01-07-2011)“…In the dentate gyrus of the hippocampus new neurons are born from precursor cells throughout development and into adulthood. These newborn neurons hold…”
Get full text
Journal Article -
12
Clustered synapses develop in distinct dendritic domains in visual cortex before eye opening
Published in eLife (11-07-2024)“…Synaptic inputs to cortical neurons are highly structured in adult sensory systems, such that neighboring synapses along dendrites are activated by similar…”
Get full text
Journal Article -
13
Somatostatin interneurons restrict cell recruitment to retinally driven spontaneous activity in the developing cortex
Published in Cell reports (Cambridge) (06-07-2021)“…During early development, before the eyes open, synaptic refinement of sensory networks depends on activity generated by developing neurons themselves. In the…”
Get full text
Journal Article -
14
Low-cost reversible tandem lens mesoscope for brain imaging in rodents
Published in Neurophotonics (Print) (01-01-2024)“…The development of imaging systems that are cost-efficient and modular is essential for modern neuroscience research. In the current study, we designed,…”
Get full text
Journal Article -
15
Disruption of Critical Period Plasticity in a Mouse Model of Neurofibromatosis Type 1
Published in The Journal of neuroscience (08-07-2020)“…Neurofibromatosis type 1 (NF1) is a common monogenic neurodevelopmental disorder associated with physical and cognitive problems. The cognitive issues are…”
Get full text
Journal Article -
16
Plasticity-dependent changes in metabotropic glutamate receptor expression at excitatory hippocampal synapses
Published in Molecular and cellular neuroscience (01-03-2008)“…Group I metabotropic glutamate receptors, mGluR1 and mGluR5, modulate NMDA receptor-mediated synaptic transmission and plasticity and mediate mGluR-dependent…”
Get full text
Journal Article -
17
Clustered synapses develop in distinct dendritic domains in visual cortex before eye opening
Published in eLife (11-07-2024)“…Synaptic inputs to cortical neurons are highly structured in adult sensory systems, such that neighboring synapses along dendrites are activated by similar…”
Get full text
Journal Article