Search Results - "Chew, Wei Xiang"
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1
Branched microtubule nucleation and dynein transport organize RanGTP asters in Xenopus laevis egg extract
Published in Molecular biology of the cell (01-01-2024)“…Chromosome segregation relies on the correct assembly of a bipolar spindle. Spindle pole self-organization requires dynein-dependent microtubule (MT) transport…”
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Journal Article -
2
Effects of microtubule length and crowding on active microtubule network organization
Published in iScience (17-02-2023)“…Active filament networks can organize into various dynamic architectures driven by cross-linking motors. Densities and kinetic properties of motors and…”
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Journal Article -
3
Surface reaction-diffusion kinetics on lattice at the microscopic scale
Published in Physical review. E (19-04-2019)“…Microscopic models of reaction-diffusion processes on the cell membrane can link local spatiotemporal effects to macroscopic self-organized patterns often…”
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Journal Article -
4
Cross-linker design determines microtubule network organization by opposing motors
Published in Proceedings of the National Academy of Sciences - PNAS (16-08-2022)“…During cell division, cross-linking motors determine the architecture of the spindle, a dynamic microtubule network that segregates the chromosomes in…”
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Journal Article -
5
Regulation of minimal spindle midzone organization by mitotic kinases
Published in Nature communications (29-10-2024)“…During cell division, the microtubule cytoskeleton undergoes dramatic cell cycle-driven reorganizations of its architecture. Coordinated by changes in the…”
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Journal Article -
6
Cooperativity transitions driven by higher-order oligomer formations in ligand-induced receptor dimerization
Published 13-12-2019“…Phys. Rev. E 100, 062407 (2019) While cooperativity in ligand-induced receptor dimerization has been linked with receptor-receptor couplings via minimal…”
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Journal Article -
7
Simulation of live-cell imaging system reveals hidden uncertainties in cooperative binding measurements
Published 04-07-2019“…1 July 2019 issue of Physical Review E (Vol. 100, No. 1) We propose a computational method to quantitatively evaluate the systematic uncertainties that arise…”
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Journal Article -
8
Surface reaction-diffusion kinetics on lattice at the microscopic scale
Published 17-11-2018“…Phys. Rev. E 99, 042411 (2019) Microscopic models of reaction-diffusion processes on the cell membrane can link local spatiotemporal effects to macroscopic…”
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Journal Article -
9
Reaction-diffusion kinetics on lattice at the microscopic scale
Published 01-09-2018“…Phys. Rev. E 98, 032418 (2018) Lattice-based stochastic simulators are commonly used to study biological reaction-diffusion processes. Some of these schemes…”
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Journal Article -
10
Cooperativity transitions driven by higher-order oligomer formations in ligand-induced receptor dimerization
Published in Physical review. E (13-12-2019)“…While cooperativity in ligand-induced receptor dimerization has been linked with receptor-receptor couplings via minimal representations of physical…”
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Journal Article -
11
Simulation of live-cell imaging system reveals hidden uncertainties in cooperative binding measurements
Published in Physical review. E (03-07-2019)“…We propose a computational method to quantitatively evaluate the systematic uncertainties that arise from undetectable sources in biological measurements using…”
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Journal Article -
12
Microscopic Lattice Method for Studying Intracellular Reaction-diffusion Kinetics
Published 01-01-2019“…Reaction and diffusion plays fundamental roles in many intracellular biochemical process. Bottom-up modelling approaches provide a way to connect the…”
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Dissertation -
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Study of Particle Dynamics in Dusty Plasma System Using Stochastic Models
Published 01-01-2013“…Dusty plasma typically consists of electrons and ions with micron-size charged dust particles. Due to complex inter-species interactions, the system…”
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Dissertation