Search Results - "Chevrier, Anik"

Rotator cuff repair: a review of surgical techniques, animal models, and new technologies under development by Deprés-tremblay, Gabrielle, BSc, Chevrier, Anik, PhD, Snow, Martyn, MD, Hurtig, Mark B., DVM, Rodeo, Scott, MD, Buschmann, Michael D., PhD

“…Rotator cuff tears are the most common musculoskeletal injury occurring in the shoulder. Current surgical repair fails to heal in 20% to 95% of patients,…”
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Manufacturing Process Affects Coagulation Kinetics of Ortho-R, an Injectable Chitosan-Platelet-Rich Plasma Biomaterial for Tissue Repair by Chevrier, Anik, Lavertu, Marc

“…Ortho-R (ChitogenX Inc., Kirkland, QC, Canada) is an injectable combination drug-biologic product that is used as an adjunct to augment the standard of care…”
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Injectable Lyophilized Chitosan-Thrombin-Platelet-Rich Plasma (CS-FIIa-PRP) Implant to Promote Tissue Regeneration: In Vitro and Ex Vivo Solidification Properties by Milano, Fiona, Chevrier, Anik, De Crescenzo, Gregory, Lavertu, Marc

“…Freeze-dried chitosan formulations solubilized in platelet-rich plasma (PRP) are currently evaluated as injectable implants with the potential for augmenting…”
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Meniscus structure in human, sheep, and rabbit for animal models of meniscus repair by Chevrier, Anik, Nelea, Monica, Hurtig, Mark B., Hoemann, Caroline D., Buschmann, Michael D.

“…Meniscus injury is a frequently encountered clinical orthopedic issue and is epidemiologically correlated to osteoarthritis. The development of new treatments…”
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Characterization of Subchondral Bone Repair for Marrow-Stimulated Chondral Defects and Its Relationship to Articular Cartilage Resurfacing by Chen, Hongmei, Chevrier, Anik, Hoemann, Caroline D., Sun, Jun, Ouyang, Wei, Buschmann, Michael D.

“…Background Microfracture and drilling are bone marrow–stimulation techniques that initiate cartilage repair by providing access to cell populations in…”
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Depth of subchondral perforation influences the outcome of bone marrow stimulation cartilage repair by Chen, Hongmei, Hoemann, Caroline D., Sun, Jun, Chevrier, Anik, McKee, Marc D., Shive, Matthew S., Hurtig, Mark, Buschmann, Michael D.

“…Subchondral drilling and microfracture are bone marrow stimulation techniques commonly used for the treatment of cartilage defects. Few studies to date have…”
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Chitosan–Platelet-Rich Plasma Implants Improve Rotator Cuff Repair in a Large Animal Model: Pivotal Study by Chevrier, Anik, Hurtig, Mark B., Lavertu, Marc

“…The purpose of this study was to assess the safety and efficacy of chitosan–platelet-rich plasma (PRP) hybrid implants used as an adjunct to surgical rotator…”
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Chitosan-Glycerol Phosphate/Blood Implants Improve Hyaline Cartilage Repair in Ovine Microfracture Defects by Hoemann, Caroline D., Hurtig, Mark, Rossomacha, Evgeny, Sun, Jun, Chevrier, Anik, Shive, Matthew S., Buschmann, Michael D.

“…Background: Microfracture is a surgical procedure that is used to treat focal articular cartilage defects. Although joint function improves following…”
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Young adult chondrocytes proliferate rapidly and produce a cartilaginous tissue at the gel-media interface in agarose cultures by Tran-Khanh, Nicolas, Chevrier, Anik, Lascau-Coman, Viorica, Hoemann, Caroline D, Buschmann, Michael D

“…Primary chondrocytes cultured in agarose can escape the gel, accumulate at the interface between agarose and the culture medium, and form an outgrowing tissue…”
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Robust Segmentation-Free Algorithm for Homogeneity Quantification in Images by Milano, Fiona, Chevrier, Anik, De Crescenzo, Gregory, Lavertu, Marc

“…Objective: Homogeneity is a notion used to describe images in various fields and is often linked to critical aspects of those fields. However, this term is…”
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siRNA Delivery with Chitosan: Influence of Chitosan Molecular Weight, Degree of Deacetylation, and Amine to Phosphate Ratio on in Vitro Silencing Efficiency, Hemocompatibility, Biodistribution, and in Vivo Efficacy by Alameh, Mohamad, Lavertu, Marc, Tran-Khanh, Nicolas, Chang, Chi-Yuan, Lesage, Frederic, Bail, Martine, Darras, Vincent, Chevrier, Anik, Buschmann, Michael D

“…Chitosan (CS) shows in vitro and in vivo efficacy for siRNA delivery but with contradictory findings for incompletely characterized systems. For understanding…”
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Chitosan-platelet-rich plasma implants improve rotator cuff repair in a large animal model: Pilot study by Chevrier, Anik, Hurtig, Mark B, Lavertu, Marc

“…Freeze-dried formulations of chitosan can be solubilized in platelet-rich plasma (PRP) to form injectable implants that are used as an adjunct treatment during…”
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Electromechanical probe and automated indentation maps are sensitive techniques in assessing early degenerated human articular cartilage by Sim, Sotcheadt, Chevrier, Anik, Garon, Martin, Quenneville, Eric, Lavigne, Patrick, Yaroshinsky, Alex, Hoemann, Caroline D., Buschmann, Michael D.

“…ABSTRACT Recent advances in the development of new drugs to halt or even reverse the progression of Osteoarthritis at an early‐stage requires new tools to…”
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Lyophilisation and concentration of chitosan/siRNA polyplexes: Influence of buffer composition, oligonucleotide sequence, and hyaluronic acid coating by Veilleux, Daniel, Gopalakrishna Panicker, Rajesh Krishnan, Chevrier, Anik, Biniecki, Kristof, Lavertu, Marc, Buschmann, Michael D.

“…[Display omitted] Chitosan (CS)/siRNA polyplexes have great therapeutic potential for treating multiple diseases by gene silencing. However, clinical…”
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Injectable freeze‐dried chitosan‐platelet‐rich‐plasma implants improve marrow‐stimulated cartilage repair in a chronic‐defect rabbit model by Dwivedi, Garima, Chevrier, Anik, Hoemann, Caroline D., Buschmann, Michael D.

“…Bone‐marrow stimulation (BMS) improves knee‐joint function but elicits incomplete repair. Liquid chitosan (CS)–glycerol phosphate/blood clots have been shown…”
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A multivalent mRNA-LNP vaccine protects against Clostridioides difficile infection by Alameh, Mohamad-Gabriel, Semon, Alexa, Bayard, Nile U, Pan, Yi-Gen, Dwivedi, Garima, Knox, James, Glover, Rochelle C, Rangel, Paula C, Tanes, Ceylan, Bittinger, Kyle, She, Qianxuan, Hu, Haitao, Bonam, Srinivasa Reddy, Maslanka, Jeffrey R, Planet, Paul J, Moustafa, Ahmed M, Davis, Benjamin, Chevrier, Anik, Beattie, Mitchell, Ni, Houping, Blizard, Gabrielle, Furth, Emma E, Mach, Robert H, Lavertu, Marc, Sellmyer, Mark A, Tam, Ying, Abt, Michael C, Weissman, Drew, Zackular, Joseph P

“…infection (CDI) is an urgent public health threat with limited preventative options. In this work, we developed a messenger RNA (mRNA)-lipid nanoparticle (LNP)…”
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Interspecies comparison of subchondral bone properties important for cartilage repair by Chevrier, Anik, Kouao, Ahou S. M., Picard, Genevieve, Hurtig, Mark B., Buschmann, Michael D.

“…ABSTRACT Microfracture repair tissue in young adult humans and in rabbit trochlea is frequently of higher quality than in corresponding ovine or horse models…”
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Chitosan inhibits platelet-mediated clot retraction, increases platelet-derived growth factor release, and increases residence time and bioactivity of platelet-rich plasma in vivo by Deprés-Tremblay, Gabrielle, Chevrier, Anik, Tran-Khanh, Nicolas, Nelea, Monica, Buschmann, Michael D

“…Platelet-rich plasma (PRP) has been used to treat different orthopedic conditions, however, the clinical benefits of using PRP remain uncertain. Chitosan…”
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Freeze-dried chitosan-platelet-rich plasma implants improve supraspinatus tendon attachment in a transosseous rotator cuff repair model in the rabbit by Deprés-Tremblay, Gabrielle, Chevrier, Anik, Snow, Martyn, Rodeo, Scott, Buschmann, Michael D

“…Rotator cuff tears result in shoulder pain, stiffness, weakness and loss of motion. After surgical repair, high failure rates have been reported based on…”
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Chondroinduction Is the Main Cartilage Repair Response to Microfracture and Microfracture With BST-CarGel: Results as Shown by ICRS-II Histological Scoring and a Novel Zonal Collagen Type Scoring Method of Human Clinical Biopsy Specimens by Hoemann, Caroline D., Tran-Khanh, Nicolas, Chevrier, Anik, Chen, Gaoping, Lascau-Coman, Viorica, Mathieu, Colleen, Changoor, Adele, Yaroshinsky, Alex, McCormack, Robert G., Stanish, William D., Buschmann, Michael D.

“…Background: Current cartilage repair histological scoring systems are unable to explain the relationship between collagen type II deposition and overall repair…”
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