Search Results - "Chevillet, John R"

Absolute quantification by droplet digital PCR versus analog real-time PCR by Hindson, Christopher M, Chevillet, John R, Briggs, Hilary A, Gallichotte, Emily N, Ruf, Ingrid K, Hindson, Benjamin J, Vessella, Robert L, Tewari, Muneesh

“…Droplet digital PCR shows greater precision and reproducibility but no consistent gain in sensitivity when compared to real-time PCR. Nanoliter-sized droplet…”
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Quantitative and stoichiometric analysis of the microRNA content of exosomes by Chevillet, John R., Kang, Qing, Ruf, Ingrid K., Briggs, Hilary A., Vojtech, Lucia N., Hughes, Sean M., Cheng, Heather H., Arroyo, Jason D., Meredith, Emily K., Gallichotte, Emily N., Pogosova-Agadjanyan, Era L., Morrissey, Colm, Stirewalt, Derek L., Hladik, Florian, Yu, Evan Y., Higano, Celestia S., Tewari, Muneesh

“…Exosomes have been proposed as vehicles for microRNA (miRNA) -based intercellular communication and a source of miRNA biomarkers in bodily fluids. Although…”
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Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma by Arroyo, Jason D, Chevillet, John R, Kroh, Evan M, Ruf, Ingrid K, Pritchard, Colin C, Gibson, Donald F, Mitchell, Patrick S, Bennett, Christopher F, Pogosova-Agadjanyan, Era L, Stirewalt, Derek L, Tait, Jonathan F, Tewari, Muneesh

“…MicroRNAs (miRNAs) circulate in the bloodstream in a highly stable, extracellular form and are being developed as blood-based biomarkers for cancer and other…”
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Issues and prospects of microRNA-based biomarkers in blood and other body fluids by Chevillet, John R, Lee, Inyoul, Briggs, Hilary A, He, Yuqing, Wang, Kai

“…Cell-free circulating microRNAs (miRNAs) in the blood are good diagnostic biomarker candidates for various physiopathological conditions, including cancer,…”
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Tumor characterization by ultrasound-release of multiple protein and microRNA biomarkers, preclinical and clinical evidence by D'Souza, Aloma L, Chevillet, John R, Ghanouni, Pejman, Yan, Xinrui, Tewari, Muneesh, Gambhir, Sanjiv S

“…We have previously shown that low frequency ultrasound can release biomarkers from cells into the murine circulation enabling an amplification and localization…”
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Multiple Integrated Copies and High-Level Production of the Human Retrovirus XMRV (Xenotropic Murine Leukemia Virus-Related Virus) from 22Rv1 Prostate Carcinoma Cells by KNOUF, Emily C, METZGER, Michael J, MITCHELL, Patrick S, ARROYO, Jason D, CHEVILLET, John R, TEWARI, Muneesh, DUSTY MILLER, A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Identification and characterization of small-molecule inhibitors of hepsin by Chevillet, John R, Park, Gemma J, Bedalov, Antonio, Simon, Julian A, Vasioukhin, Valeri I

“…Hepsin is a type II transmembrane serine protease overexpressed in the majority of human prostate cancers. We recently demonstrated that hepsin promotes…”
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Droplet Digital PCR for Absolute Quantification of Extracellular MicroRNAs in Plasma and Serum: Quantification of the Cancer Biomarker hsa-miR-141 by Giraldez, Maria D, Chevillet, John R, Tewari, Muneesh

“…Droplet-based digital PCR provides high-precision, absolute quantification of nucleic acid target sequences with wide-ranging applications for both research…”
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Release of Cell-free MicroRNA Tumor Biomarkers into the Blood Circulation with Pulsed Focused Ultrasound: A Noninvasive, Anatomically Localized, Molecular Liquid Biopsy by Chevillet, John R, Khokhlova, Tatiana D, Giraldez, Maria D, Schade, George R, Starr, Frank, Wang, Yak-Nam, Gallichotte, Emily N, Wang, Kai, Hwang, Joo Ha, Tewari, Muneesh

“…Purpose To compare the abilities of three pulsed focused ultrasound regimes (that cause tissue liquefaction, permeabilization, or mild heating) to release…”
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A Microfluidic Device to Enhance Viral Transduction Efficiency During Manufacture of Engineered Cellular Therapies by Moore, Nathan, Chevillet, John R., Healey, Laura J., McBrine, Connor, Doty, Daniel, Santos, Jose, Teece, Bryan, Truslow, James, Mott, Vienna, Hsi, Peter, Tandon, Vishal, Borenstein, Jeffrey T., Balestrini, Jenna, Kotz, Kenneth

“…The development and approval of engineered cellular therapies are revolutionizing approaches to treatment of diseases. However, these life-saving therapies…”
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High intensity focused ultrasound-induced bubbles stimulate the release of nucleic acid cancer biomarkers by Khokhlova, Tatiana, Chevillet, John R., Schade, George R., Giraldez, Maria D., Wang, Yak-Nam, Hwang, Joo Ha, Tewari, Muneesh

“…Recently, several nucleic acid cancer biomarkers, e.g., microRNA and mutant DNA, have been identified and shown promise for improving cancer diagnostics…”
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Abstract 1118: Circulating microRNA biomarkers for cancer exist in multiple biophysical states by Chevillet, John R., Gallichotte, Emily N., Cheng, Heather H., Vojtech, Lucia N., Arroyo, Jason D., Briggs, Hilary, Vessella, Robert L., Higano, Celestia S., Yu, Evan Y., Pogosova-Agadjanyan, Era L., Stirewalt, Derek L., Hladik, Florian, Tewari, Muneesh

“…Abstract MicroRNAs (miRNAs) are small regulatory RNA molecules that function in a wide range of normal and pathologic cellular processes. Cell-free miRNAs…”
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Abstract 4881: A novel method of tumor characterization by protein and microRNA biomarker release using ultrasound by D'Souza, Aloma L., Chevillet, John R., Kroh, Evan M., Tewari, Muneesh, Gambhir, Sanjiv S., Glazer, Gary M.

“…Abstract Earlier cancer diagnosis and monitoring of therapy could be improved by the earlier detection of circulating biomarkers. Ultrasound at low frequencies…”
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Micro-RNA Detection Using Nanopore Force Spectroscopy with MspA by Derrington, Ian M., Feldman, David J., Gundlach, Jens H., Parkin, Rachael K., Chevillet, John R., Tewari, Muneesh

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Hepsin in prostate cancer progression by Chevillet, John R

“…Although significant progress has been made in our understanding of prostate cancer progression and metastasis, much remains unknown and therapeutic approaches…”
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