Search Results - "Chevalier, Annick"
-
1
Atezolizumab plus bevacizumab and chemotherapy for metastatic, persistent, or recurrent cervical cancer (BEATcc): a randomised, open-label, phase 3 trial
Published in The Lancet (British edition) (06-01-2024)“…The GOG240 trial established bevacizumab with chemotherapy as standard first-line therapy for metastatic or recurrent cervical cancer. In the BEATcc trial…”
Get full text
Journal Article -
2
Immune tumor microenvironnement (iTME) post-neoadjuvant chemotherapy, beyond PD-L1: Novel immune targets in ovarian cancer, data from the CHIVA trial, a GINECO/GINEGEPS study
Published in Journal of clinical oncology (01-06-2022)“…5554 Background: Antibodies targeting PDL1 or PD1 have been disappointing so far in the treatment of ovarian cancer (OC). A greater understanding of the…”
Get full text
Journal Article -
3
Victoria: A multicentric, randomized, open-label, phase I/II of mTOR inhibitor (VISTUSERTIB) combined with anastrozole in patients with hormone receptor-positive advanced/metastatic endometrial cancer—A CLIPP program INCA in collaboration with GINECO group
Published in Journal of clinical oncology (20-05-2021)“…Abstract only 5507 Background: Endometrial carcinoma is generally hormone dependent and aromatase inhibitors are used in routine practice before or after 1 st…”
Get full text
Journal Article -
4
Multicentre randomized phase II trial of olaparib as maintenance therapy in platinum-sensitive advanced endometrial carcinoma: The GINECO-UTOLA study
Published in Journal of clinical oncology (20-05-2020)“…Abstract only TPS6109 Background: Advanced endometrial cancer (EC) patients relapse despite treatment with combination chemotherapy and have a short…”
Get full text
Journal Article -
5
Impact of adding nintedanib to neoadjuvant chemotherapy (NACT) for advanced epithelial ovarian cancer (EOC) patients: The CHIVA double-blind randomized phase II GINECO study
Published in Journal of clinical oncology (20-05-2019)“…Abstract only 5512 Background: Nintedanib, an oral inhibitor of VEGF-FGF-PDGF receptors, has been shown to prolong progression-free survival (PFS) when added…”
Get full text
Journal Article -
6
Modeled CA-125 kinetics during neoadjuvant chemotherapy for predicting the likelihood of optimal interval debulking surgery in ovarian cancer patients: Data from CHIVA trial (a GINECO study)
Published in Journal of clinical oncology (20-05-2019)“…Abstract only 5546 Background: A pre-operative predictive biomarker of CC0 interval debulking surgery (IDS) likelihood would be helpful. The modeled CA125…”
Get full text
Journal Article -
7
A New Paradigm in Managing Advanced Ovarian Cancer: Differentiating Patients Requiring Neoadjuvant Treatment from Primary Cytoreduction
Published in Cancers (30-09-2021)“…Our study aims to evaluate the comparability of primary debulking surgery (PDS) and neoadjuvant chemotherapy (NACT) patients. This single-center retrospective…”
Get full text
Journal Article -
8
CA-125 ELIMination Rate Constant K (KELIM) Is a Marker of Chemosensitivity in Patients with Ovarian Cancer: Results from the Phase II CHIVA Trial
Published in Clinical cancer research (01-09-2020)“…In patients with ovarian cancer receiving neoadjuvant chemotherapy, the first-line treatment success will depend on both the tumor-primary chemosensitivity and…”
Get full text
Journal Article -
9
A RAD51 functional assay as a candidate test for homologous recombination deficiency in ovarian cancer
Published in Gynecologic oncology (01-04-2023)“…Homologous recombination deficiency (HRD), defined as BRCA1/2 mutation (BRCAmut) or high genomic instability, is used to identify ovarian cancer (OC) patients…”
Get full text
Journal Article -
10
Safety and Efficacy of the mTOR Inhibitor, Vistusertib, Combined With Anastrozole in Patients With Hormone Receptor-Positive Recurrent or Metastatic Endometrial Cancer: The VICTORIA Multicenter, Open-label, Phase 1/2 Randomized Clinical Trial
Published in JAMA oncology (01-07-2022)“…Endometrial cancer is often hormone-dependent and treated with aromatase inhibitors. The PI3K-AKT-mTOR pathway deregulation observed in endometrial cancer…”
Get more information
Journal Article -
11
Corrigendum to “A RAD51 functional assay as a candidate test for homologous recombination deficiency in ovarian cancer”
Published in Gynecologic oncology (01-08-2023)Get full text
Journal Article -
12
Validation of the Clinical Use of GIScar, an Academic-developed Genomic Instability Score Predicting Sensitivity to Maintenance Olaparib for Ovarian Cancer
Published in Clinical cancer research (01-11-2023)“…Abstract Purpose: The optimal application of maintenance PARP inhibitor therapy for ovarian cancer requires accessible, robust, and rapid testing of homologous…”
Get full text
Journal Article -
13
Comparative analysis of predictive values of the kinetics of 11 circulating miRNAs and of CA125 in ovarian cancer during first line treatment (a GINECO study)
Published in Gynecologic oncology (01-10-2020)“…MicroRNAs (miRNAs) are promising biomarkers in ovarian cancer. Their kinetics during treatment might be useful for monitoring disease burden, and guiding…”
Get full text
Journal Article -
14
Effect of Weekly Paclitaxel With or Without Bevacizumab on Progression-Free Rate Among Patients With Relapsed Ovarian Sex Cord-Stromal Tumors: The ALIENOR/ENGOT-ov7 Randomized Clinical Trial
Published in JAMA oncology (01-12-2020)“…To our knowledge, this is the first randomized trial in sex cord-stromal tumors, and it establishes weekly paclitaxel as standard-of-care therapy after…”
Get more information
Journal Article -
15
What is new in the surgical treatment of pelvic gynecologic cancers?
Published in Bulletin du cancer (01-01-2006)“…General tendency of modern cancerology is the research of adequacy between extent of disease and treatments. This concept is of course valid for gynaecology…”
Get more information
Journal Article -
16
Surgical staging of early invasive epithelial ovarian tumors
Published in Seminars in surgical oncology (01-07-2000)“…Early stage epithelial ovarian carcinoma is defined pathologically as a tumor strictly limited to one or both ovaries without any extra‐ovarian disease (i.e.,…”
Get full text
Journal Article -
17
MR imaging of endometrial carcinoma: role and limits
Published in Bulletin du cancer (01-11-2002)“…To assess the MR imaging (MRI) in initial decision making of endometrial carcinoma. From january 1997 to march 2002, 86 patients with clinical stage I…”
Get full text
Journal Article -
18
Frequency of genetic diseases and cancer antecedents in 493 adults with visceral or soft tissue sarcomas
Published in Bulletin du cancer (01-10-2003)“…Little is known about epidemiology of adults soft tissue and visceral sarcomas (ASTS). The frequency of previous cancers and associated genetic diseases has…”
Get full text
Journal Article -
19
Actualités chirurgicales dans les cancers gynécologiques pelviens
Published in Bulletin du cancer (2006)Get full text
Journal Article -
20
IRM des cancers de l'endomètre : apports et limites
Published in Bulletin du cancer (01-11-2002)Get full text
Journal Article