Search Results - "Cheung, Timothy"

Learning critically drives parkinsonian motor deficits through imbalanced striatal pathway recruitment by Cheung, Timothy H C, Ding, Yunmin, Zhuang, Xiaoxi, Kang, Un Jung

“…Dopamine (DA) loss in Parkinson's disease (PD) causes debilitating motor deficits. However, dopamine is also widely linked to reward prediction and learning,…”
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Systems-level comparison of host-responses elicited by avian H5N1 and seasonal H1N1 influenza viruses in primary human macrophages by Lee, Suki M Y, Gardy, Jennifer L, Cheung, C Y, Cheung, Timothy K W, Hui, Kenrie P Y, Ip, Nancy Y, Guan, Y, Hancock, Robert E W, Peiris, J S Malik

“…Human disease caused by highly pathogenic avian influenza (HPAI) H5N1 can lead to a rapidly progressive viral pneumonia leading to acute respiratory distress…”
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Toll-like receptor 10 is involved in induction of innate immune responses to influenza virus infection by Lee, Suki M. Y., Kok, Kin-Hang, Jaume, Martial, Cheung, Timothy K. W., Yip, Tsz-Fung, Lai, Jimmy C. C., Yi Guan, Webster, Robert G., Jin, Dong-Yan, Peiris, J. S. Malik

“…Toll-like receptors (TLRs) play key roles in innate immune recognition of pathogen-associated molecular patterns of invading microbes. Among the 10 TLR family…”
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The signaling networks of the herpesvirus entry mediator (TNFRSF14) in immune regulation by Steinberg, Marcos W., Cheung, Timothy C., Ware, Carl F.

“…The tumor necrosis factor (TNF) receptor superfamily member herpesvirus entry mediator (HVEM) (TNFRSF14) regulates T‐cell immune responses by activating both…”
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BK channel density is regulated by endoplasmic reticulum associated degradation and influenced by the SKN-1A/NRF1 transcription factor by Cheung, Timothy P, Choe, Jun-Yong, Richmond, Janet E, Kim, Hongkyun

“…Ion channels are present at specific levels within subcellular compartments of excitable cells. The regulation of ion channel trafficking and targeting is an…”
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Protein Release by Controlled Desorption from Transiently Cationic Nanoparticles by Cheung, Timothy H., Xue, Chang, Kurtz, Daniel A., Shoichet, Molly S.

“…Therapeutic release from hydrogels is traditionally controlled by encapsulation within nanoparticles; however, this strategy is limited for the release of…”
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Dopamine D3 and 5-HT1B receptor dysregulation as a result of psychostimulant intake and forced abstinence: Implications for medications development by Neisewander, Janet L., Cheung, Timothy H.C., Pentkowski, Nathan S.

“…Addiction to psychostimulants, including cocaine and amphetamine, is associated with dysregulation of dopamine and serotonin (5-HT) neurotransmitter systems…”
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Vacuum-Assisted Eggshell-Type Bone Debridement with Implantation of Antibiotic-Impregnated Bone Substitute for Treatment of Calcaneal Osteomyelitis with Subsequent Charcot's Reconstruction: A Case Report by Yonemoto, Grant, Cheung, Timothy P, Vyce, Steven D, Gazes, Michael I

“…Charcot's neuroarthropathy complicated by calcaneal osteomyelitis can be difficult to treat. Various surgical techniques describe how to manage these…”
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Extinction under a behavioral microscope: Isolating the sources of decline in operant response rate by Cheung, Timothy H.C., Neisewander, Janet L., Sanabria, Federico

“…► A novel model separating extinction performance into its behavioral components. ► We illustrate the use of the model with two working examples. ► We describe…”
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Social context has differential effects on acquisition of nicotine self-administration in male and female rats by Peartree, Natalie A., Hatch, Kayla N., Goenaga, Julianna G., Dado, Nora R., Molla, Hanna, Dufwenberg, Martin A., Campagna, Allegra, Mendoza, Rachel, Cheung, Timothy H.C., Talboom, Joshua S., Neisewander, Janet L.

“…Rational Smoking typically begins during adolescence or early adulthood in a social context, yet the role of social context in animal models is poorly…”
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A bout analysis of operant response disruption by Brackney, Ryan J., Cheung, Timothy H.C., Sanabria, Federico

“…•The organization of operant behavior was disrupted in two strains of rat.•Extinction progressively reduced the rate at which response bouts were…”
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A review of the phytochemical and pharmacological properties of Amauroderma rugosum by Zheng, Cheng‐Wen, Cheung, Timothy Man‐Yau, Leung, George Pak‐Heng

“…Amauroderma rugosum (AR) is a basidiomycete in the Ganodermataceae family that has been used traditionally to prevent epileptic attacks and constant crying in…”
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Biology of Influenza A Virus by CHEUNG, TIMOTHY K. W., POON, LEO L. M.

“…:  The outbreaks of avian influenza A virus in poultry and humans over the last decade posed a pandemic threat to human. Here, we discuss the basic…”
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Minocycline-Induced Black Bone Disease in Foot and Ankle Surgery: A Case Report by Rashid, Arij M, Cheung, Timothy P, Paracha, Rumzah, Vitale, Glenn C, Vyce, Steven D

“…Bone and periarticular tissue discoloration can be an unexpected finding that is often disconcerting for surgeons and may alter surgical plans and overall…”
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Neuroprotective Effects of Polysaccharides and Gallic Acid from Amauroderma rugosum against 6-OHDA-Induced Toxicity in SH-SY5Y Cells by Rangsinth, Panthakarn, Pattarachotanant, Nattaporn, Wang, Wen, Shiu, Polly Ho-Ting, Zheng, Chengwen, Li, Renkai, Tencomnao, Tewin, Chuchawankul, Siriporn, Prasansuklab, Anchalee, Cheung, Timothy Man-Yau, Li, Jingjing, Leung, George Pak-Heng

“…The pharmacological activity and medicinal significance of (AR) have rarely been documented. We examined the antioxidant and neuroprotective effects of AR on…”
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A new criterion for acquisition of nicotine self-administration in rats by Peartree, Natalie A, Sanabria, Federico, Thiel, Kenneth J, Weber, Suzanne M, Cheung, Timothy H.C, Neisewander, Janet L

“…Abstract Background Acquisition of nicotine self-administration in rodents is relatively difficult to establish and measures of acquisition rate are sometimes…”
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Epitope topography of agonist antibodies to the checkpoint inhibitory receptor BTLA by Cheung, Timothy C., Atwell, Shane, Bafetti, Lisa, Cuenca, Paulina Delgado, Froning, Karen, Hendle, Jorg, Hickey, Michael, Ho, Carolyn, Huang, Jiawen, Lieu, Ricky, Lim, Stacie, Lippner, David, Obungu, Victor, Ward-Kavanagh, Lindsay, Weichert, Kenneth, Ware, Carl F., Vendel, Andrew C.

“…B and T lymphocyte attenuator (BTLA) is an attractive target for a new class of therapeutics that attempt to rebalance the immune system by agonizing…”
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Amauroderma rugosum Extract Suppresses Inflammatory Responses in Tumor Necrosis Factor Alpha/Interferon Gamma-Induced HaCaT Keratinocytes by Shiu, Polly Ho-Ting, Li, Jingjing, Zheng, Chengwen, Rangsinth, Panthakarn, Li, Renkai, Cheung, Queenie Tze-Lam, Lau, Angel Heng-Yee, Chan, Jacqueline Cho-Ki, Kwan, Yiu-Wa, Cheung, Timothy Man-Yau, Leung, George Pak-Heng

“…Keratinocytes form the physical barrier of the skin and play an important role in the inflammatory process. Amauroderma rugosum is an edible mushroom; however,…”
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Hippocampal lesions facilitate instrumental learning with delayed reinforcement but induce impulsive choice in rats by Cheung, Timothy H C, Cardinal, Rudolf N

“…Animals must frequently act to influence the world even when the reinforcing outcomes of their actions are delayed. Learning with action-outcome delays is a…”
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THE ISOLATION OF MOTIVATIONAL, MOTORIC, AND SCHEDULE EFFECTS ON OPERANT PERFORMANCE: A MODELING APPROACH by Brackney, Ryan J., Cheung, Timothy H. C., Neisewander, Janet L., Sanabria, Federico

“…Dissociating motoric and motivational effects of pharmacological manipulations on operant behavior is a substantial challenge. To address this problem, we…”
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