Search Results - "Cheung, Sally W.T."
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A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface
Published in Cell (03-12-2015)“…The centrosome is the primary microtubule organizing center of the cells and templates the formation of cilia, thereby operating at a nexus of…”
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CEP120 and SPICE1 Cooperate with CPAP in Centriole Elongation
Published in Current biology (22-07-2013)“…Centrosomes organize microtubule (MT) arrays and are comprised of centrioles surrounded by ordered pericentriolar proteins [1–4]. Centrioles are barrel-shaped…”
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The Deubiquitinase USP37 Regulates Chromosome Cohesion and Mitotic Progression
Published in Current biology (31-08-2015)“…A bipolar mitotic spindle facilitates the equal segregation of chromosomes to two daughter cells. To achieve bipolar attachment of microtubules to kinetochores…”
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Developmentally Programmed Nuclear Destruction during Yeast Gametogenesis
Published in Developmental cell (17-07-2012)“…Autophagy controls cellular catabolism in diverse eukaryotes and modulates programmed cell death in plants and animals. While studies of the unicellular yeast…”
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A proximity-dependent biotinylation map of a human cell
Published in Nature (London) (01-07-2021)“…Compartmentalization is a defining characteristic of eukaryotic cells, and partitions distinct biochemical processes into discrete subcellular locations…”
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Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators
Published in Cell reports (Cambridge) (22-11-2016)“…Reversible phosphorylation is a fundamental regulatory mechanism, intricately coordinated by kinases and phosphatases, two classes of enzymes widely disrupted…”
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Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly
Published in Nature communications (30-04-2018)“…Centrosomes are required for faithful chromosome segregation during mitosis. They are composed of a centriole pair that recruits and organizes the…”
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Programmed nuclear destruction in yeast: Self-eating by vacuolar lysis
Published in Autophagy (01-02-2013)“…Studies of the budding yeast Saccharomyces cerevisiae have provided many of the most important insights into the mechanisms of autophagy, which are common to…”
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