Search Results - "Cheung, Ronald"

Recent insights into the molecular basis of Fanconi anemia: genes, modifiers, and drivers by Cheung, Ronald S., Taniguchi, Toshiyasu

“…Fanconi anemia (FA), the most common form of inherited bone marrow failure, predisposes to leukemia and solid tumors. FA is caused by the genetic disruption of…”
Get full text

FANCI Regulates Recruitment of the FA Core Complex at Sites of DNA Damage Independently of FANCD2 by Castella, Maria, Jacquemont, Celine, Thompson, Elizabeth L, Yeo, Jung Eun, Cheung, Ronald S, Huang, Jen-Wei, Sobeck, Alexandra, Hendrickson, Eric A, Taniguchi, Toshiyasu

“…The Fanconi anemia (FA)-BRCA pathway mediates repair of DNA interstrand crosslinks. The FA core complex, a multi-subunit ubiquitin ligase, participates in the…”
Get full text

Diagnostic accuracy of current machine learning classifiers for age-related macular degeneration: a systematic review and meta-analysis by Cheung, Ronald, Chun, Jacob, Sheidow, Tom, Motolko, Michael, Malvankar-Mehta, Monali S.

“…Background and objective The objective of this study was to systematically review and meta-analyze the diagnostic accuracy of current machine learning…”
Get full text

Endoscopic management of Wirsungocele with recurrent acute pancreatitis by Cheung, Ronald L Y, Chan, Shannon M, Yip, Hon C, Teoh, Anthony Y B

Get more information

Ubiquitination-Linked Phosphorylation of the FANCI S/TQ Cluster Contributes to Activation of the Fanconi Anemia I/D2 Complex by Cheung, Ronald S., Castella, Maria, Abeyta, Antonio, Gafken, Philip R., Tucker, Nyka, Taniguchi, Toshiyasu

“…Repair of interstrand crosslinks by the Fanconi anemia (FA) pathway requires both monoubiquitination and de-ubiquitination of the FANCI/FANCD2 (FANCI/D2)…”
Get full text

Percutaneous cholecystostomy for high-risk patients with acute cholangitis by Li, Yan-Lin, Wong, Kin-Hoi, Chiu, Keith Wan-Hang, Cheng, Andrew Kai-Chun, Cheung, Ronald Kin-On, Yam, Max Kai-Ho, Chan, Angie Lok-Chi, Chan, Victor Siang-Hua, Law, Martin Wai-Ming, Lee, Paul Sing-Fun

“…Percutaneous cholecystostomy (PC) is a well-established treatment for acute cholecystitis. We investigate the performance and role of PC in managing acute…”
Get full text

Lower-intensity CPX-351 plus venetoclax induction for adults with newly diagnosed AML unfit for intensive chemotherapy by Uy, Geoffrey L, Pullarkat, Vinod A, Baratam, Praneeth, Stuart, Robert K, Walter, Roland B, Winer, Eric S, Wang, Qi, Faderl, Stefan, Chakravarthy, Divya, Menno, Diane, Cheung, Ronald S, Lin, Tara L

“…Preclinical data suggest a rationale for combining CPX-351, a dual-drug liposomal encapsulation of daunorubicin and cytarabine, with venetoclax, a B-cell…”
Get full text

CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI by Hu, Wen-Feng, Krieger, Kimiko L., Lagundžin, Dragana, Li, Xueli, Cheung, Ronald S., Taniguchi, Toshiyasu, Johnson, Keith R., Bessho, Tadayoshi, Monteiro, Alvaro N. A., Woods, Nicholas T.

“…BRCA1 C-terminal domains are found in a specialized group of 23 proteins that function in the DNA damage response to protect genomic integrity. C-terminal…”
Get full text

p53-R273H gains new function in induction of drug resistance through down-regulation of procaspase-3 by Wong, Ronald Pak Cheung, Tsang, Wing Pui, Chau, Pui Yee, Co, Ngai Na, Tsang, Tsun Yee, Kwok, Tim Tak

“…Development of drug resistance is one of the major obstacles in cancer chemotherapy. The molecular mechanism leading to drug resistance is still not fully…”
Get full text

Interactions between MYC and transforming growth factor alpha alter the growth and tumorigenicity of liver progenitor cells by Cheung, Ronald S.Y., Brooling, John T., Johnson, Melissa M., Riehle, Kimberly J., Campbell, Jean S., Fausto, Nelson

“…The MYC oncogene induces both cell proliferation and apoptosis. The apoptotic function of MYC is thought to inhibit carcinogenesis; thus, when disrupted,…”
Get full text

CPX-351, a Dual-Drug Liposomal Formulation, Alleviates the Cardiotoxicity of Daunorubicin and Cytarabine to Induced Human Pluripotent Stem Cell-Derived Cardiomyocytes by Fortin, Marie C., LaCroix, Andrew, Wang, Qi, Cheung, Ronald S.

“…Introduction: CPX-351 (US: Vyxeos ®; EU: Vyxeos ® Liposomal), a dual-drug liposomal encapsulation of daunorubicin + cytarabine at a synergistic 1:5 molar…”
Get full text

Population Pharmacokinetic-Pharmacodynamic Modeling of Neutrophil and Platelet Count for Lower-Intensity Therapy of CPX-351 Combined with Venetoclax in Acute Myeloid Leukemia by Liang, Yali, Cook, Sarah F, Cheung, Ronald, Zhou, Honghui, Coppola, Sheryl, Wang, Qi, Mager, Donald E, Van Wart, Scott A

“…Background: Improved survival outcomes and a comparable safety profile with CPX-351 (a dual-drug liposomal encapsulation of daunorubicin and cytarabine in a…”
Get full text

Evaluating the Short-term Environmental and Clinical Effects of a Radiation Oncology Department's Response to the COVID-19 Pandemic by Cheung, Ronald, Ito, Emma, Lopez, Marianela, Rubinstein, Ed, Keller, Harald, Cheung, Fred, Liu, Zhihui Amy, Liu, Fei-Fei, Wong, Philip

“…During the COVID-19 pandemic, many radiation oncology departments worldwide adopted the use of shorter and more intense hypofractionated regimens. Hospital…”
Get full text

Effectiveness of Machine Learning Classifiers for Cataract Screening by Cheung, Ronald

“…Cataract is the leading cause of blindness and vision loss globally. The implementation of artificial intelligence (AI) in the healthcare industry has been on…”
Get full text

Risk of Parkinson's disease in glaucoma patients: a systematic review and meta-analysis by Zhao, Bill, Cheung, Ronald, Malvankar-Mehta, Monali S.

“…To conduct a systematic review and meta-analysis to evaluate the relationship between glaucoma and the risk of Parkinson's disease. A systematic search of…”
Get full text

The Prevalence of Occupational Burnout Among Ophthalmologists: A Systematic Review and Meta-Analysis by Cheung, Ronald, Yu, Brian, Iordanous, Yiannis, Malvankar-Mehta, Monali S.

“…Objective To investigate the prevalence of occupational burnout among ophthalmologists in order to better understand the mental and physical well-being of eye…”
Get full text

58: Evaluating the Short-Term Environmental and Clinical Effects of a Radiation Oncology Department’s Response to the COVID-19 Pandemic (STEER COVID-19) by Wong, Philip, Cheung, Ronald, Ito, Emma, Lopez, Marianela, Rubinstein, Ed, Keller, Harald, Cheung, Fred, Liu, Zhihui Amy, Liu, Fei-Fei

Get full text

295 Influence of Socio-Economic Status on Radiotherapy Adverse Events by Wong, Philip, Dhivagaran, Thanansayan, Cheung, Ronald, Ito, Emma, Chan, Kitty, So, Nathaniel, Keller, Harald, Cheung, Frederick, Rubinstein, Edward, Liu, Zhihui Amy, Tsang, Richard

Get full text

Lower-Intensity CPX-351 + Venetoclax for Patients with Newly Diagnosed Acute Myeloid Leukemia Who Are Unfit for Intensive Chemotherapy: Post Hoc Analysis By Disease Risk Subgroups by Lin, Tara L., Baratam, Praneeth, Stuart, Robert K., Walter, Roland B., Winer, Eric S., Faderl, Stefan, Chandrasekaran, Vijayalakshmi, Chakravarthy, Divya, Cheung, Ronald S., Pullarkat, Vinod A.

Get full text

Comparing the diagnostic accuracy of telemedicine utilization versus in-person clinical examination for retinopathy of prematurity in premature infants: a systematic review by Li, Wanjin, Cheung, Ronald, Malvankar-Mehta, Monali S.

“…To synthesize the literature assessing the diagnostic accuracy of telemedicine evaluation compared with clinical examination for retinopathy of prematurity…”
Get full text