Search Results - "Cheung, Julie F."

Mechanism of early dissemination and metastasis in Her2+ mammary cancer by Harper, Kathryn L., Sosa, Maria Soledad, Entenberg, David, Hosseini, Hedayatollah, Cheung, Julie F., Nobre, Rita, Avivar-Valderas, Alvaro, Nagi, Chandandaneep, Girnius, Nomeda, Davis, Roger J., Farias, Eduardo F., Condeelis, John, Klein, Christoph A., Aguirre-Ghiso, Julio A.

“…Two related papers show that cells disseminated from malignant lesions at early time points during tumorigenesis can contribute to metastases at distant organs…”
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Priming of myelin-specific T cells in the absence of dendritic cells results in accelerated development of Experimental Autoimmune Encephalomyelitis by Luu, Thaiphi, Cheung, Julie F, Baccon, Jennifer, Waldner, Hanspeter

“…Experimental autoimmune encephalomyelitis (EAE) is an established animal model of multiple sclerosis (MS). Inflammatory CD4+ T cell responses directed against…”
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Neoantigen-driven B cell and CD4 T follicular helper cell collaboration promotes anti-tumor CD8 T cell responses by Cui, Can, Wang, Jiawei, Fagerberg, Eric, Chen, Ping-Min, Connolly, Kelli A., Damo, Martina, Cheung, Julie F., Mao, Tianyang, Askari, Adnan S., Chen, Shuting, Fitzgerald, Brittany, Foster, Gena G., Eisenbarth, Stephanie C., Zhao, Hongyu, Craft, Joseph, Joshi, Nikhil S.

“…CD4 T follicular helper (TFH) cells support B cells, which are critical for germinal center (GC) formation, but the importance of TFH-B cell interactions in…”
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Phenotypic heterogeneity of disseminated tumour cells is preset by primary tumour hypoxic microenvironments by Fluegen, Georg, Avivar-Valderas, Alvaro, Wang, Yarong, Padgen, Michael R., Williams, James K., Nobre, Ana Rita, Calvo, Veronica, Cheung, Julie F., Bravo-Cordero, Jose Javier, Entenberg, David, Castracane, James, Verkhusha, Vladislav, Keely, Patricia J., Condeelis, John, Aguirre-Ghiso, Julio A.

“…Hypoxia is a poor-prognosis microenvironmental hallmark of solid tumours, but it is unclear how it influences the fate of disseminated tumour cells (DTCs) in…”
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A reservoir of stem-like CD8 + T cells in the tumor-draining lymph node preserves the ongoing antitumor immune response by Connolly, Kelli A, Kuchroo, Manik, Venkat, Aarthi, Khatun, Achia, Wang, Jiawei, William, Ivana, Hornick, Noah I, Fitzgerald, Brittany L, Damo, Martina, Kasmani, Moujtaba Y, Cui, Can, Fagerberg, Eric, Monroy, Isabel, Hutchins, Amanda, Cheung, Julie F, Foster, Gena G, Mariuzza, Dylan L, Nader, Mursal, Zhao, Hongyu, Cui, Weiguo, Krishnaswamy, Smita, Joshi, Nikhil S

“…“Stem-like” TCF1 CD8 T (T ) cells are necessary for long-term maintenance of T cell responses and the efficacy of immunotherapy, but, as tumors contain signals…”
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IL-7R licenses a population of epigenetically poised memory CD8 + T cells with superior antitumor efficacy that are critical for melanoma memory by Micevic, Goran, Daniels, Andrew, Flem-Karlsen, Karine, Park, Koonam, Talty, Ronan, McGeary, Meaghan, Mirza, Haris, Blackburn, Holly N, Sefik, Esen, Cheung, Julie F, Hornick, Noah I, Aizenbud, Lilach, Joshi, Nikhil S, Kluger, Harriet, Iwasaki, Akiko, Bosenberg, Marcus W, Flavell, Richard A

“…Recurrence of advanced melanoma after therapy is a major risk factor for reduced survival, and treatment options are limited. Antitumor immune memory plays a…”
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A PERK-Specific Inhibitor Blocks Metastatic Progression by Limiting Integrated Stress Response-Dependent Survival of Quiescent Cancer Cells by Calvo, Veronica, Zheng, Wei, Adam-Artigues, Anna, Staschke, Kirk A, Huang, Xin, Cheung, Julie F, Nobre, Ana Rita, Fujisawa, Sho, Liu, David, Fumagalli, Maria, Surguladze, David, Stokes, Michael E, Nowacek, Ari, Mulvihill, Mark, Farias, Eduardo F, Aguirre-Ghiso, Julio A

“…The integrated stress response (ISR) kinase PERK serves as a survival factor for both proliferative and dormant cancer cells. We aim to validate PERK…”
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Inducible de novo expression of neoantigens in tumor cells and mice by Damo, Martina, Fitzgerald, Brittany, Lu, Yisi, Nader, Mursal, William, Ivana, Cheung, Julie F., Connolly, Kelli A., Foster, Gena G., Akama-Garren, Elliot, Lee, Da-Yae, Chang, Greg P., Gocheva, Vasilena, Schmidt, Leah M., Boileve, Alice, Wilson, Josephine H., Cui, Can, Monroy, Isabel, Gokare, Prashanth, Cabeceiras, Peter, Jacks, Tyler, Joshi, Nikhil S.

“…Inducible expression of neoantigens in mice would enable the study of endogenous antigen-specific naïve T cell responses in disease and infection, but has been…”
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Bone marrow NG2 + /Nestin + mesenchymal stem cells drive DTC dormancy via TGFβ2 by Nobre, Ana Rita, Risson, Emma, Singh, Deepak K, Di Martino, Julie S, Cheung, Julie F, Wang, Jiapeng, Johnson, John, Russnes, Hege G, Bravo-Cordero, Jose Javier, Birbrair, Alexander, Naume, Bjorn, Azhar, Mohamad, Frenette, Paul S, Aguirre-Ghiso, Julio A

“…In the bone marrow (BM) microenvironment, where breast cancer (BC) disseminated tumour cells (DTCs) can remain dormant for decades, NG2 /Nestin mesenchymal…”
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Corrigendum: Mechanism of early dissemination and metastasis in Her2 + mammary cancer by Harper, Kathryn L, Sosa, Maria Soledad, Entenberg, David, Hosseini, Hedayatollah, Cheung, Julie F, Nobre, Rita, Avivar-Valderas, Alvaro, Nagi, Chandandaneep, Girnius, Nomeda, Davis, Roger J, Farias, Eduardo F, Condeelis, John, Klein, Christoph A, Aguirre-Ghiso, Julio A

“…This corrects the article DOI: 10.1038/nature20609…”
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A mouse model for the study of anti-tumor T cell responses in Kras-driven lung adenocarcinoma by Fitzgerald, Brittany, Connolly, Kelli A., Cui, Can, Fagerberg, Eric, Mariuzza, Dylan L., Hornick, Noah I., Foster, Gena G., William, Ivana, Cheung, Julie F., Joshi, Nikhil S.

“…Kras-driven lung adenocarcinoma (LUAD) is the most common lung cancer. A significant fraction of patients with Kras-driven LUAD respond to immunotherapy, but…”
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1025 Tumor-specific CD8+ T cells epigenetically licensed by IL-7R are critical for anti-tumor immunity in melanoma by Micevic, Goran, Daniels, Andrew, Flem-Karlsen, Karine, Park, Koonam, Talty, Ronan, McGeary, Meaghan, Mirza, Haris, Blackburn, Holly N, Sefik, Esen, Cheung, Julie F, Hornick, Noah, Aizenbud, Lilach, Joshi, Nikhil, Kluger, Harriet, Iwasaki, Akiko, Bosenberg, Marcus, Flavell, Richard

“…BackgroundRecurrence of advanced melanoma after checkpoint therapy is a major risk factor for death, and treatment options are limited. Anti-tumor memory plays…”
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Diverse Models of Immunoediting: Exploring Tumor-T Cell Interactions in Developing Cancers by Cheung, Julie F

“…Cancer's complexity is characterized by its genetic diversity, adaptability to environmental changes, and the extent of immunoediting that results from…”
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Correction: Corrigendum: Mechanism of early dissemination and metastasis in Her2.sup.+ mammary cancer by Harper, Kathryn L, Sosa, Maria Soledad, Entenberg, David, Hosseini, Hedayatollah, Cheung, Julie F, Nobre, Rita, Avivar-Valderas, Alvaro

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Inducible de novo expression of neoantigens in tumor cells and mice with NINJA by Damo, Martina, Fitzgerald, Brittany, Lu, Yisi, Nader, Mursal, William, Ivana, Cheung, Julie F., Connolly, Kelli A., Foster, Gena G., Akama-Garren, Elliot, Lee, Da-Yae, Chang, Greg P., Gocheva, Vasilena, Schmidt, Leah M., Boileve, Alice, Wilson, Josephine H., Cui, Can, Monroy, Isabel, Gokare, Prashanth, Cabeceiras, Peter, Jacks, Tyler, Joshi, Nikhil S.

“…Inducible expression of neoantigens in mice would enable the study of endogenous antigen-specific naïve T cell responses in disease and infection, but has been…”
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Abstract B030: Productive T-cell-mediated immunoediting of developing sarcomas by distinct mechanisms by Hunt, Brian G, Cheung, Julie F., Venkatesan, Srividhya, Loza, Jennifer L., Connolly, Kelli A., Wahed, Shudipto, Cheng, Elaine, Bansal, Ishan, Borr, Emily, Wei, Wei, William, Ivana, Fitzgerald, Brittany, Joshi, Nikhil

“…Immunoediting is the process where developing tumors are shaped by cells of the immune system. Tumors with low immunogenicity are likely to emerge after…”
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Correction: Corrigendum: Mechanism of early dissemination and metastasis in Her2+ mammary cancer by Harper, Kathryn L., Sosa, Maria Soledad, Entenberg, David, Hosseini, Hedayatollah, Cheung, Julie F., Nobre, Rita, Avivar-Valderas, Alvaro, Nagi, Chandandaneep, Girnius, Nomeda, Davis, Roger J., Farias, Eduardo F., Condeelis, John, Klein, Christoph A., Aguirre-Ghiso, Julio A.

“…Nature 540, 588–592 (2016); doi:10.1038/nature20609 In Extended Data Fig. 4g of this Letter, the image showing the rabbit IgG control (top image) was…”
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Erratum: Corrigendum: Mechanism of early dissemination and metastasis in Her2+ mammary cancer by Harper, Kathryn L., Sosa, Maria Soledad, Entenberg, David, Hosseini, Hedayatollah, Cheung, Julie F., Nobre, Rita, Avivar-Valderas, Alvaro, Nagi, Chandandaneep, Girnius, Nomeda, Davis, Roger J., Farias, Eduardo F., Condeelis, John, Klein, Christoph A., Aguirre-Ghiso, Julio A.

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Mechanism of early dissemination and metastasis in Her2^sup +^ mammary cancer by Harper, Kathryn L, Sosa, Maria Soledad, Entenberg, David, Hosseini, Hedayatollah, Cheung, Julie F, Nobre, Rita, Avivar-Valderas, Alvaro, Nagi, Chandandaneep, Girnius, Nomeda, Davis, Roger J, Farias, Eduardo F, Condeelis, John, Klein, Christoph A, Aguirre-Ghiso, Julio A

“…Metastasis is the leading cause of cancer-related deaths; metastatic lesions develop from disseminated cancer cells (DCCs) that can remain dormant1…”
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Abstract A43: Phenotypic heterogeneity of disseminated tumor cells is predetermined by primary tumor hypoxic microenvironments by Fluegen, Georg, Avivar-Valderas, Alvaro, Wang, Yarong, Padgen, Michael R., Williams, James K., Verkhusha, Vladislav, Cheung, Julie F., Entenberg, David, Castracane, James, Keely, Patricia J., Condeelis, John, Aguirre-Ghiso, Julio A.

“…Heterogeneity within and between primary tumors (PTs) is reflected by genetic and epigenetic diversity and varying PT microenvironments. Further, whether PT…”
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