Search Results - "Cheung, Joyce"
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Structure of an activated DNA-PK and its implications for NHEJ
Published in Molecular cell (18-02-2021)“…DNA-dependent protein kinase (DNA-PK), like all phosphatidylinositol 3-kinase-related kinases (PIKKs), is composed of conserved FAT and kinase domains…”
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2
A role for the HOXB7 homeodomain protein in DNA repair
Published in Cancer research (Chicago, Ill.) (15-02-2007)“…Homeobox genes encode transcription factors which function in body axis patterning in the developing embryo. Recent evidence suggests that the maintenance of…”
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3
Suppression of erythropoiesis in malarial anemia is associated with hemozoin in vitro and in vivo
Published in Blood (15-10-2006)“…Malarial anemia is a global public health problem and is characterized by a low reticulocyte response in the presence of life-threatening hemolysis. Although…”
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4
Looking Beyond the Cell in Cellulitis
Published in Advances in skin & wound care (01-05-2017)“…BACKGROUND:Patients with erythematous skin are likely to receive a diagnosis of cellulitis; however, the accuracy of this diagnosis is approximately only 33%…”
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5
Surgical vein graft preparation promotes cellular dysfunction, oxidative stress, and intimal hyperplasia in human saphenous vein
Published in Journal of vascular surgery (01-07-2014)“…Introduction Human saphenous vein (HSV) is the most widely used bypass conduit for peripheral and coronary vascular reconstructions. However, outcomes are…”
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6
FNDC3B is another novel partner fused to RARA in the t(3;17)(q26;q21) variant of acute promyelocytic leukemia
Published in Blood (11-05-2017)Get full text
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7
Evidence for an inositol hexakisphosphate-dependent role for Ku in mammalian nonhomologous end joining that is independent of its role in the DNA-dependent protein kinase
Published in Nucleic acids research (01-10-2008)“…Nonhomologous end-joining (NHEJ) is an important pathway for the repair of DNA double-strand breaks (DSBs) and plays a critical role in maintaining genomic…”
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Combined effects of sensory cueing and limb activation on unilateral neglect in subacute left hemiplegic stroke patients: a randomized controlled pilot study
Published in Clinical rehabilitation (01-07-2013)“…Objective: To compare the effects of contralesional sensory cueing and limb activation with that of sham control in the treatment of unilateral neglect after…”
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9
Deep genomic characterization highlights complexities and prognostic markers of pediatric acute myeloid leukemia
Published in Communications biology (31-03-2023)“…Pediatric acute myeloid leukemia (AML) is an uncommon but aggressive hematological malignancy. The poor outcome is attributed to inadequate prognostic…”
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10
Bile diversion to the distal small intestine has comparable metabolic benefits to bariatric surgery
Published in Nature communications (21-07-2015)“…Roux-en-Y gastric bypass (RYGB) is highly effective in reversing obesity and associated diabetes. Recent observations in humans suggest a contributing role of…”
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11
Anxiety and Mood Disorders and Cannabis Use
Published in The American journal of drug and alcohol abuse (01-03-2010)“…Background: Cannabis use has been linked to anxiety and mood disorders (AMD) in clinical cases, but little research on this relationship has been reported at…”
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12
The Hsp90-binding peptidylprolyl isomerase FKBP52 potentiates glucocorticoid signaling in vivo
Published in The EMBO journal (03-03-2003)“…Hsp90 is required for the normal activity of steroid receptors, and in steroid receptor complexes it is typically bound to one of the immunophilin‐related…”
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13
Blocking P2X7 receptor with AZ 10606120 exacerbates vascular hyperpermeability and inflammation in murine polymicrobial sepsis
Published in Physiological reports (01-06-2022)“…Sepsis is a devastating disease with high morbidity and mortality and no specific treatments. The pathophysiology of sepsis involves a hyperinflammatory…”
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14
Promoting effectiveness of “working from home”: findings from Hong Kong working population under COVID-19
Published in Asian education and development studies (11-03-2021)“…PurposeWorking-from-home (WFH) practice has been adopted by many companies of a variety of industries in a diverse manner; however, it is not until the recent…”
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15
An anionic, endosome-escaping polymer to potentiate intracellular delivery of cationic peptides, biomacromolecules, and nanoparticles
Published in Nature communications (01-11-2019)“…Peptides and biologics provide unique opportunities to modulate intracellular targets not druggable by conventional small molecules. Most peptides and…”
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The Difference Between Critical Care Initiation Anion Gap and Prehospital Admission Anion Gap is Predictive of Mortality in Critical Illness
Published in Critical care medicine (2013)“…We hypothesized that the delta anion gap defined as difference between critical care initiation standard anion gap and prehospital admission standard anion gap…”
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17
Mutational spectrum and prognosis in Chinese patients with prefibrotic primary myelofibrosis
Published in EJHaem (01-02-2022)“…Prefibrotic primary myelofibrosis (Pre‐PMF) has been classified as a separate entity of myeloproliferative neoplasms (MPNs). Pre‐PMF is clinically…”
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18
Prevalence of Problematic Video Gaming among Ontario Adolescents
Published in International journal of mental health and addiction (01-12-2012)“…Video game playing has become a very popular activity among adolescents. Its impact on the mental health and well-being of players is just beginning to be…”
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19
A novel NUP98-JADE2 fusion in a patient with acute myeloid leukemia resembling acute promyelocytic leukemia
Published in Blood advances (25-01-2022)“…Acute promyelocytic leukemia (APL) is a specific subtype of acute myeloid leukemia (AML) characterized by block of differentiation at the promyelocytic stage…”
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20
Cell-free hemoglobin increases inflammation, lung apoptosis, and microvascular permeability in murine polymicrobial sepsis
Published in PloS one (03-02-2020)“…Increased endothelial permeability is central to the pathogenesis of sepsis and leads to organ dysfunction and death but the endogenous mechanisms that drive…”
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