Search Results - "Cheung, Jerry S."

Quantitative chemical exchange saturation transfer (CEST) MRI of glioma using Image Downsampling Expedited Adaptive Least-squares (IDEAL) fitting by Zhou, Iris Yuwen, Wang, Enfeng, Cheung, Jerry S., Zhang, Xiaoan, Fulci, Giulia, Sun, Phillip Zhe

“…Chemical Exchange Saturation Transfer (CEST) MRI is sensitive to dilute metabolites with exchangeable protons, allowing tissue characterization in diseases…”
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Association between pH-weighted endogenous amide proton chemical exchange saturation transfer MRI and tissue lactic acidosis during acute ischemic stroke by Sun, Phillip Zhe, Cheung, Jerry S, Wang, Enfeng, Lo, Eng H

“…The ischemic tissue becomes acidic after initiation of anaerobic respiration, which may result in impaired tissue metabolism and, ultimately, in severe tissue…”
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Simulation and optimization of pulsed radio frequency irradiation scheme for chemical exchange saturation transfer (CEST) MRI-demonstration of pH-weighted pulsed-amide proton CEST MRI in an animal model of acute cerebral ischemia by Sun, Phillip Zhe, Wang, Enfeng, Cheung, Jerry S., Zhang, Xiaoan, Benner, Thomas, Sorensen, A. Gregory

“…Chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) is capable of measuring dilute labile protons and microenvironmental properties…”
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Direct saturation‐corrected chemical exchange saturation transfer MRI of glioma: Simplified decoupling of amide proton transfer and nuclear overhauser effect contrasts by Yuwen Zhou, Iris, Wang, Enfeng, Cheung, Jerry S., Lu, Dongshuang, Ji, Yang, Zhang, Xiaoan, Fulci, Giulia, Sun, Phillip Zhe

“…Purpose Chemical exchange saturation transfer (CEST) MRI has shown promise in tissue characterization in diseases like stroke and tumor. However, in vivo CEST…”
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Suppression of Liver Tumor Growth and Metastasis by Adiponectin in Nude Mice through Inhibition of Tumor Angiogenesis and Downregulation of Rho Kinase/IFN-Inducible Protein 10/Matrix Metalloproteinase 9 Signaling by Man, Kwan, Ng, Kevin T P, Xu, Aimin, Cheng, Qiao, Lo, Chung Mau, Xiao, Jiang Wei, Sun, Bai Shun, Lim, Zophia X H, Cheung, Jerry S, Wu, Ed X, Sun, Chris K W, Poon, Ronnie T P, Fan, Sheung Tat

“…Purpose: We aimed to investigate the effects of adiponectin on liver cancer growth and metastasis and explore the underlying mechanisms. Experimental Design:…”
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Diffusion tensor imaging of renal ischemia reperfusion injury in an experimental model by Cheung, Jerry S., Fan, Shu Juan, Chow, April M., Zhang, Jingbo, Man, Kwan, Wu, Ed X.

“…Renal ischemia reperfusion injury (IRI) is a major cause of acute renal failure. It occurs in various clinical settings such as renal transplantation, shock…”
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Diffusion tensor imaging of liver fibrosis in an experimental model by Cheung, Jerry S., Fan, Shu Juan, Gao, Darwin S., Chow, April M., Man, Kwan, Wu, Ed X.

“…Purpose To characterize changes in diffusion properties of liver using diffusion tensor imaging (DTI) in an experimental model of liver fibrosis. Materials and…”
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Mapping tissue pH in an experimental model of acute stroke – Determination of graded regional tissue pH changes with non-invasive quantitative amide proton transfer MRI by Wang, Enfeng, Wu, Yin, Cheung, Jerry S., Igarashi, Takahiro, Wu, Limin, Zhang, Xiaoan, Sun, Phillip Zhe

“…pH-weighted amide proton transfer (APT) MRI is sensitive to tissue pH change during acute ischemia, complementing conventional perfusion and diffusion stroke…”
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Imaging acute ischemic tissue acidosis with pH-sensitive endogenous amide proton transfer (APT) MRI—Correction of tissue relaxation and concomitant RF irradiation effects toward mapping quantitative cerebral tissue pH by Sun, Phillip Zhe, Wang, Enfeng, Cheung, Jerry S.

“…Amide proton transfer (APT) MRI is sensitive to ischemic tissue acidosis and has been increasingly used as a research tool to investigate disrupted tissue…”
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In Vivo Lipid Profiling Using Proton Magnetic Resonance Spectroscopy in an Experimental Liver Fibrosis Model by Cheung, Jerry S., PhD, Fan, Shu Juan, MSc, Gao, Darwin S., BEng, Chow, April M., PhD, Yang, Jian, MD, PhD, Man, Kwan, PhD, Wu, Ed X., PhD

“…Rationale and Objectives The aim of this study was to characterize early hepatic lipid changes in an experimental model of liver fibrosis using proton (1 H)…”
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Determination of multipool contributions to endogenous amide proton transfer effects in global ischemia with high spectral resolution in vivo chemical exchange saturation transfer MRI by Zhou, Iris Yuwen, Lu, Dongshuang, Ji, Yang, Wu, Limin, Wang, Enfeng, Cheung, Jerry S., Zhang, Xiao‐An, Sun, Phillip Zhe

“…Purpose Chemical exchange saturation transfer (CEST) MRI has been used for quantitative assessment of dilute metabolites and/or pH in disorders such as acute…”
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Multifunctional Yolk−Shell Nanoparticles: A Potential MRI Contrast and Anticancer Agent by Gao, Jinhao, Liang, Gaolin, Cheung, Jerry S, Pan, Yue, Kuang, Yi, Zhao, Fan, Zhang, Bei, Zhang, Xixiang, Wu, Ed X, Xu, Bing

“…We report a new type of multifunctional nanomaterials, FePt@Fe2O3 yolk−shell nanoparticles, that exhibit high cytotoxicity originated from the FePt yolks and…”
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Stratification of Heterogeneous Diffusion MRI Ischemic Lesion With Kurtosis Imaging Evaluation of Mean Diffusion and Kurtosis MRI Mismatch in an Animal Model of Transient Focal Ischemia by CHEUNG, Jerry S, WANG, Enfeng, LO, Eng H, PHILLIP ZHE SUN

“…Ischemic tissue damage is heterogeneous, resulting in complex patterns in the widely used diffusion-weighted MRI. Our study examined the spatiotemporal…”
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pH imaging reveals worsened tissue acidification in diffusion kurtosis lesion than the kurtosis/diffusion lesion mismatch in an animal model of acute stroke by Wang, Enfeng, Wu, Yin, Cheung, Jerry S, Zhou, Iris Yuwen, Igarashi, Takahiro, Zhang, XiaoAn, Sun, Phillip Zhe

“…Diffusion weighted imaging (DWI) has been commonly used in acute stroke examination, yet a portion of DWI lesion may be salvageable. Recently, it has been…”
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Fast multislice pH-weighted chemical exchange saturation transfer (CEST) MRI with Unevenly segmented RF irradiation by Sun, Phillip Zhe, Cheung, Jerry S., Wang, Enfeng, Benner, Thomas, Sorensen, A. Gregory

“…Chemical exchange saturation transfer (CEST) MRI is a versatile imaging technique for measuring microenvironment properties via dilute CEST labile groups…”
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In Vivo Proton Magnetic Resonance Spectroscopy of Hepatic Ischemia/Reperfusion Injury in an Experimental Model by Chow, April M., PhD, Chan, Kannie W.Y., PhD, Fan, Shu Juan, MSc, Yang, Jian, MD, PhD, Cheung, Jerry S., PhD, Khong, Pek-Lan, MD, Wu, Ed X., PhD

“…Rationale and Objectives Hepatic ischemia/reperfusion injury (IRI) occurs during certain hepatobiliary surgeries, hemorrhagic shock, and veno-occlusive…”
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Comparison of dosimetric impact of intra‐fractional setup discrepancy between multiple‐ and single‐isocenter approaches in linac‐based stereotactic radiotherapy of multiple brain metastases by Tsui, Sylvia S. W., Wu, Vincent W. C., Cheung, Jerry S. C.

“…Introduction Treatment of multiple brain metastases by linac‐based stereotactic radiotherapy (SRT) can employ either a multiple‐isocenter (MI) or…”
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A breath-hold R2 mapping pulse sequence detects a decrease in myocardial ferritin iron after one-week of iron chelation by Kim, Daniel, Wu, Ed X, Jensen, Jens, Au, Wing-Yan, Feng, Li, Cheung, Jerry S, Ha, Shau-Yin, Sheth, Sujit S, Brittenham, Gary M

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Microbubbles as a novel contrast agent for brain MRI by Cheung, Jerry S., Chow, April M., Guo, Hua, Wu, Ed X.

“…Gas-filled microbubbles have the potential to become a unique MR contrast agent due to their magnetic susceptibility effect, biocompatibility and localized…”
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Molecular MRI of Liver Fibrosis by a Peptide-Targeted Contrast Agent in an Experimental Mouse Model by Chow, April M, Tan, Mingqian, Gao, Darwin S, Fan, Shu Juan, Cheung, Jerry S, Qiao, Zhongwei, Man, Kwan, Lu, Zheng-Rong, Wu, Ed X

“…OBJECTIVESCyclic decapeptide CGLIIQKNEC (CLT1) has been demonstrated to target fibronectin-fibrin complexes in the extracellular matrix of different tumors and…”
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