Search Results - "Cheung, J R"

Reproductive and developmental safety of nirmatrelvir (PF-07321332), an oral SARS-CoV-2 M pro inhibitor in animal models by Catlin, N R, Bowman, C J, Campion, S N, Cheung, J R, Nowland, W S, Sathish, J G, Stethem, C M, Updyke, L, Cappon, G D

“…Nirmatrelvir (PF-07321332; NMV) the antiviral component of PAXLOVID™ is a potent and selective inhibitor of the SARS-CoV-2 main protease (M ), which plays a…”
Get full text

GI endoscopic reprocessing practices in the United States by Cheung, Raynard J., Ortiz, Daisy, DiMarino, Anthony J.

“…Background:  Patient infection from contaminated gastrointestinal (GI) endoscopes can generally be attributed to failure to follow appropriate reprocessing…”
Get full text

Surveillance after colorectal cancer resection by Berman, Jeffrey M, Cheung, Raynard J, Weinberg, David S

“…Berman et al conducted a MEDLINE search of all English language reports of post-operative surveillance for colorectal cancer. They reviewed all primary reports…”
Get full text

Intonation influences how children and adults interpret sarcasm by Glenwright, Melanie, Parackel, Jayanthi M, Cheung, Kristene R J, Nilsen, Elizabeth S

“…Adults distinguish sarcasm from literal language according to intonation involving a reduction in fundamental frequency (F0). We examined whether children's…”
Get more information

An evaluation of the sensitivity of the Ames assay to discern low-level mutagenic impurities by Kenyon, Michelle O., Cheung, Jennifer R., Dobo, Krista L., Ku, Warren W.

“…Low level impurities often reside in active pharmaceutical ingredients (API). Some of these impurities are potentially genotoxic since reactive intermediates…”
Get full text

Nature of N-nitrosodimethylamine demethylase and its inhibitors by YOO, J.-S. H, CHEUNG, R. J, PATTEN, C. J, WADE, D, YANG, C. S

“…The present study was undertaken to examine the nature of the low Km (KmI) form of rat liver microsomal N-nitrosodimethylamine demethylase (NDMAd) and its…”
Get full text

Repeatedly pairing vagus nerve stimulation with a movement reorganizes primary motor cortex by Porter, Benjamin A, Khodaparast, Navid, Fayyaz, Tabbassum, Cheung, Ryan J, Ahmed, Syed S, Vrana, William A, Rennaker, 2nd, Robert L, Kilgard, Michael P

“…Although sensory and motor systems support different functions, both systems exhibit experience-dependent cortical plasticity under similar conditions. If…”
Get full text

Reproductive and developmental safety of nirmatrelvir (PF-07321332), an oral SARS-CoV-2 Mpro inhibitor in animal models by Catlin, N.R., Bowman, C.J., Campion, S.N., Cheung, J.R., Nowland, W.S., Sathish, J.G., Stethem, C.M., Updyke, L., Cappon, G.D.

“…•No adverse effects of nirmatrelvir on rat fertility or reproduction.•Nirmatrelvir is not teratogenic in rats or rabbits.•No clinically relevant risks…”
Get full text

Risk to the health care worker of HIV infection and how to minimize It by Cheung, R J, DiMarino, Jr, A J

“…Occupational transmission of HIV fortunately is uncommon. The risk of acquiring HIV depends on the mode of exposure, the body fluid involved, and the source…”
Get more information

Aspirin resistance: a growing concern by Chow, Sheryl L, Cheung, Rebecca J

“…Aspirin is the cornerstone of therapy in the treatment and prevention of cardiovascular disease. The potential benefit of aspirin therapy may be significantly…”
Get full text

Bioluminescent Salmonella reverse mutation assay: a screen for detecting mutagenicity with high throughput attributes by Aubrecht, Jiri, Osowski, Jeffery J., Persaud, Prita, Cheung, Jennifer R., Ackerman, Joel, Lopes, Sarah H., Ku, Warren W.

“…Here, we describe the development and evaluation of a novel bioluminescent high-throughput Salmonella reverse mutation assay applicable to the screening of…”
Get full text

Surveillance after colorectal cancer resection by Berman, J M, Cheung, R J, Weinberg, D S

“…Despite improvements in adjuvant therapy, colorectal cancer recurs in up to half of patients in the USA, most frequently in liver, lung and locoregional…”
Get full text

A Myoclonic Reaction with Low-Dose Hydromorphone by Patel, Seema, Roshan, Veda R, Lee, Kelly C, Cheung, Rebecca J

“…Objective: To report a case of myoclonus associated with the use of a low dose of the opioid analgesic hydromorphone. Case Summary: A 55-year-old white man…”
Get full text

Acute Coffee Ingestion Does Not Affect LDL Cholesterol Level by Cheung, Rebecca J, Gupta, Eric K, Ito, Matthew K

“…BACKGROUND Although patients are instructed to abstain from food before having blood drawn for lipid analysis, many still drink coffee in the morning. It is…”
Get full text

The novel tumour suppressor gene ING1 is overexpressed in human melanoma cell lines by Campos, E.I., Cheung JR, K-J.J., Murray, A., Li, S., Li, G.

“…Summary Background Epidemiological evidence indicates that exposure to ultraviolet (UV) radiation is directly linked to the increase of both incidence and…”
Get full text

Key Articles, Guidelines, and Consensus Papers Relative to the Treatment of Dyslipidemias-2005 by Ito, Matthew K., Cheung, Rebecca J., Gupta, Eric K., Birtcher, Kimberly K., Chong, Pang H., Bianco, Theresa M., Bleske, Barry E.

“…Hypercholesterolemia is a major risk factor for development of coronary heart disease. Proper diagnosis and adequate treatment are vital to reducing morbidity…”
Get full text

Increased genetic damage in oral leukoplakia from high risk sites: Potential impact on staging and clinical management by LEWEI ZHANG, CHEUNG, K-John JR, LAM, Wan L, XING CHENG, POH, Catherine, PRIDDY, Robert, EPSTEIN, Joel, LE, Nhu D, ROSIN, Miriam P

“…Two staging systems for oral leukoplakias have been proposed to better predict prognosis. Although one system includes site as an independent determinant, its…”
Get full text

Expression of the novel tumour suppressor p33ing1 is independent of p53 by JR, K-Jj Cheung, BUSH, J. A, JIA, W, LI, G

“…A recently cloned tumour suppressor candidate, p33ING1, has been shown in vitro to collaborate with p53 to execute growth arrest and apoptosis. However, it is…”
Get full text

The tumour suppressor p33ING1 does not regulate migration and angiogenesis in melanoma cells by Cheung, Jr, K-John, Li, Gang

“…The tumour suppressor ING1 shares many biological functions with p53, such as cell cycle arrest, DNA repair, apoptosis, and chemosensitivity. Since p53…”
Get more information

The tumour suppressor p33ING1 does not enhance camptothecin-induced cell death in melanoma cells by Cheung, Jr, K-John, Li, Gang

“…The tumour suppressor ING1 shares many biological functions with p53, such as cell cycle arrest, DNA repair, apoptosis, and chemosensitivity. Previous findings…”
Get more information