Search Results - "Cheung, Crystal S F"

Natural Flanking Sequences for Peptides Included in a Quantification Concatamer Internal Standard by Cheung, Crystal S. F, Anderson, Kyle W, Wang, Meiyao, Turko, Illarion V

“…Quantification by targeted proteomics has largely depended on mass spectrometry and isotope-labeled internal standards. In addition to traditionally used…”
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Quantification of Borrelia burgdorferi Membrane Proteins in Human Serum: A New Concept for Detection of Bacterial Infection by Cheung, Crystal S. F, Anderson, Kyle W, Benitez, Kenia Y. Villatoro, Soloski, Mark J, Aucott, John N, Phinney, Karen W, Turko, Illarion V

“…The Borrelia burgdorferi spirochete is the causative agent of Lyme disease, the most common tick-borne disease in the United States. The low abundance of…”
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Broad shifts in gene expression during early postnatal life are associated with shifts in histone methylation patterns by Lui, Julian C, Chen, Weiping, Cheung, Crystal S F, Baron, Jeffrey

“…During early postnatal life, extensive changes in gene expression occur concomitantly in multiple major organs, indicating the existence of a common core…”
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Spatial regulation of gene expression during growth of articular cartilage in juvenile mice by Lui, Julian C., Chau, Michael, Chen, Weiping, Cheung, Crystal S. F., Hanson, Jeffrey, Rodriguez-Canales, Jaime, Nilsson, Ola, Baron, Jeffrey

“…Background: In juvenile mammals, the epiphyses of long bones grow by chondrogenesis within the articular cartilage. A better understanding of the molecular…”
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Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry by Lai, Yen-Ting, Wang, Tao, O’Dell, Sijy, Louder, Mark K., Schön, Arne, Cheung, Crystal S. F., Chuang, Gwo-Yu, Druz, Aliaksandr, Lin, Bob, McKee, Krisha, Peng, Dongjun, Yang, Yongping, Zhang, Baoshan, Herschhorn, Alon, Sodroski, Joseph, Bailer, Robert T., Doria-Rose, Nicole A., Mascola, John R., Langley, David R., Kwong, Peter D.

“…Diverse entry inhibitors targeting the gp120 subunit of the HIV-1 envelope (Env) trimer have been developed including BMS-626529, also called temsavir, a…”
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An influenza H1 hemagglutinin stem-only immunogen elicits a broadly cross-reactive B cell response in humans by Andrews, Sarah F, Cominsky, Lauren Y, Shimberg, Geoffrey D, Gillespie, Rebecca A, Gorman, Jason, Raab, Julie E, Brand, Joshua, Creanga, Adrian, Gajjala, Suprabhath R, Narpala, Sandeep, Cheung, Crystal S F, Harris, Darcy R, Zhou, Tongqing, Gordon, Ingelise, Holman, LaSonji, Mendoza, Floreliz, Houser, Katherine V, Chen, Grace L, Mascola, John R, Graham, Barney S, Kwong, Peter D, Widge, Alicia, Dropulic, Lesia K, Ledgerwood, Julie E, Kanekiyo, Masaru, McDermott, Adrian B

“…Current yearly seasonal influenza vaccines primarily induce an antibody response directed against the immunodominant but continually diversifying hemagglutinin…”
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A single residue in influenza virus H2 hemagglutinin enhances the breadth of the B cell response elicited by H2 vaccination by Andrews, Sarah F., Raab, Julie E., Gorman, Jason, Gillespie, Rebecca A., Cheung, Crystal S. F., Rawi, Reda, Cominsky, Lauren Y., Boyington, Jeffrey C., Creanga, Adrian, Shen, Chen-Hsiang, Harris, Darcy R., Olia, Adam S., Nazzari, Alexandra F., Zhou, Tongqing, Houser, Katherine V., Chen, Grace L., Mascola, John R., Graham, Barney S., Kanekiyo, Masaru, Ledgerwood, Julie E., Kwong, Peter D., McDermott, Adrian B.

“…Conserved epitopes on the influenza hemagglutinin (HA) stem are an attractive target for universal vaccine strategies as they elicit broadly neutralizing…”
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Preclinical evaluation of the mTOR–PI3K inhibitor BEZ235 in nasopharyngeal cancer models by Ma, Brigette B.Y, Lui, Vivian W.Y, Hui, Connie W.C, Lau, Cecilia P.Y, Wong, Chi H, Hui, Edwin P, Ng, Margaret H.L, Cheng, Suk H, Tsao, Sai W, Tsang, Chi-Man, Cheung, Crystal S.F, Ho, Kakiu, Chan, Anthony T.C

“…Abstract The dual PI3K–mTOR inhibitor BEZ235 was evaluated in preclinical models of nasopharyngeal carcinoma (NPC). The IC50 value of BEZ235 for growth was in…”
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Preclinical evaluation of sunitinib as single agent or in combination with chemotherapy in nasopharyngeal carcinoma by Hui, Edwin Pun, Lui, Vivian W. Y., Wong, Cesar S. C., Ma, Brigette B. Y., Lau, Cecilia P. Y., Cheung, Crystal S. F., Ho, Kakiu, Cheng, Suk-hang, Ng, Margaret H. L., Chan, Anthony T. C.

“…Summary Purpose : Sunitinib is a multi-target receptor tyrosine kinase (RTK) inhibitor against vascular endothelial growth factor receptors, platelet-derived…”
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Identification of chondrocyte-binding peptides by phage display by Cheung, Crystal S.F., Lui, Julian C., Baron, Jeffrey

“…ABSTRACT As an initial step toward targeting cartilage tissue for potential therapeutic applications, we sought cartilage‐binding peptides using phage display,…”
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A new approach to quantification of mAb aggregates using peptide affinity probes by Cheung, Crystal S. F., Anderson, Kyle W., Patel, Pooja M., Cade, Keale L., Phinney, Karen W., Turko, Illarion V.

“…Using mAbs as therapeutic molecules is complicated by the propensity of mAbs to aggregate at elevated concentrations, which can lead to a variety of adverse…”
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Evolutionary conservation and modulation of a juvenile growth-regulating genetic program by Delaney, Angela, Padmanabhan, Vasantha, Rezvani, Geoffrey, Chen, Weiping, Forcinito, Patricia, Cheung, Crystal S F, Baron, Jeffrey, Lui, Julian C K

“…Body size varies enormously among mammalian species. In small mammals, body growth is typically suppressed rapidly, within weeks, whereas in large mammals,…”
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Editor’s Focus by Lui, Julian C., Chau, Michael, Chen, Weiping, Cheung, Crystal S. F., Hanson, Jeffrey, Rodriguez-Canales, Jaime, Nilsson, Ola, Baron, Jeffrey

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Broad Shifts in Gene Expression during Early Postnatal Life Are Associated with Shifts in Histone Methylation Patterns: e86957 by Lui, Julian C, Chen, Weiping, Cheung, Crystal SF, Baron, Jeffrey

“…During early postnatal life, extensive changes in gene expression occur concomitantly in multiple major organs, indicating the existence of a common core…”
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