Search Results - "Cheung, Alison M"
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Cell segmentation for immunofluorescence multiplexed images using two-stage domain adaptation and weakly labeled data for pre-training
Published in Scientific reports (15-03-2022)“…Cellular profiling with multiplexed immunofluorescence (MxIF) images can contribute to a more accurate patient stratification for immunotherapy. Accurate cell…”
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Therapy-Induced Acute Recruitment of Circulating Endothelial Progenitor Cells to Tumors
Published in Science (American Association for the Advancement of Science) (22-09-2006)“…The contribution of bone marrow-derived circulating endothelial progenitor cells (CEPs) to tumor angiogenesis has been controversial, primarily because of…”
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Targeted anti-vascular endothelial growth factor receptor-2 therapy leads to short-term and long-term impairment of vascular function and increase in tumor hypoxia
Published in Cancer research (Chicago, Ill.) (01-04-2006)“…Because antiangiogenic therapies inhibit the growth of new tumor-associated blood vessels, as well as prune newly formed vasculature, they would be expected to…”
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Brca2 deficiency does not impair mammary epithelium development but promotes mammary adenocarcinoma formation in p53+/- mutant mice
Published in Cancer research (Chicago, Ill.) (15-03-2004)“…Brca2 is an important tumor suppressor associated with susceptibility to breast cancer. Although increasing evidence indicates that the primary function of…”
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Microultrasound Molecular Imaging of Vascular Endothelial Growth Factor Receptor 2 in a Mouse Model of Tumor Angiogenesis
Published in Molecular imaging (01-09-2007)“…High-frequency microultrasound imaging of tumor progression in mice enables noninvasive anatomic and functional imaging at excellent spatial and temporal…”
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What's new in Shock, December 2011?
Published in Shock (Augusta, Ga.) (01-12-2011)Get full text
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Ki-67 Membranous Staining: Biologically Relevant or an Artifact of Multiplexed Immunofluorescent Staining
Published in Applied immunohistochemistry & molecular morphology (01-07-2016)“…In the process of developing a multiplex of 8 common breast cancer biomarkers (Her2/neu, estrogen receptor, progesterone receptor, Ki-67, aldehyde…”
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Detecting Vascular Changes in Tumour Xenografts Using Micro-Ultrasound and Micro-CT Following Treatment with VEGFR-2 Blocking Antibodies
Published in Ultrasound in medicine & biology (01-08-2007)“…Abstract Blockade of vascular endothelial growth factor (VEGF) binding to its receptors on endothelial cells has been shown preclinically to induce tumour…”
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PTEN in the haematopoietic system and its therapeutic indications
Published in Trends in molecular medicine (01-11-2006)“…A unique feature of the haematopoietic system is its self-renewal ability while maintaining a stable number of pluripotent haematopoietic stem cells (HSCs)…”
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Interframe Clutter Filtering for High Frequency Flow Imaging
Published in Ultrasound in medicine & biology (01-04-2007)“…Abstract This study investigates ‘interframe’ clutter filtering with a high frequency (HF) flow imaging system with the objective of improving the performance…”
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Loss of Brca2 and p53 synergistically promotes genomic instability and deregulation of T-cell apoptosis
Published in Cancer research (Chicago, Ill.) (01-11-2002)“…BRCA2 is a breast cancer susceptibility gene of which the product is thought to be involved in monitoring genome integrity and cell cycle progression…”
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Abstract PO-084: Protein marker heterogeneity in breast cancer subtypes measured using immunofluorescence protein multiplexing and quantitative, single cell image analysis
Published in Cancer research (Chicago, Ill.) (01-11-2020)“…The extent of intra-tumoral heterogeneity - the variation in the composition of cells in a given tumor and those in the local tumor microenvironment - could…”
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Abstract 5622: Integrative cross-platform characterisation of mammographic screen-detected breast cancer
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Mammography screening is widely used for earlier detection of breast cancer and has been shown to contribute to reduction of mortality and morbidity. Most…”
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Three-dimensional ultrasound biomicroscopy for xenograft growth analysis
Published in Ultrasound in medicine & biology (01-06-2005)“…We reported the use of high-frequency ultrasound biomicroscopy (UBM) in the quantitative analysis of early tumor growth in mice bearing melanoma xenografts in…”
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