Search Results - "Cheung, Alison"

Cell segmentation for immunofluorescence multiplexed images using two-stage domain adaptation and weakly labeled data for pre-training by Han, Wenchao, Cheung, Alison M., Yaffe, Martin J., Martel, Anne L.

“…Cellular profiling with multiplexed immunofluorescence (MxIF) images can contribute to a more accurate patient stratification for immunotherapy. Accurate cell…”
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Therapy-Induced Acute Recruitment of Circulating Endothelial Progenitor Cells to Tumors by Shaked, Yuval, Ciarrocchi, Alessia, Franco, Marcela, Lee, Christina R, Man, Shan, Cheung, Alison M, Hicklin, Daniel J, Chaplin, David, Foster, F. Stuart, Benezra, Robert, Kerbel, Robert S

“…The contribution of bone marrow-derived circulating endothelial progenitor cells (CEPs) to tumor angiogenesis has been controversial, primarily because of…”
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Quantitative single-cell analysis of immunofluorescence protein multiplex images illustrates biomarker spatial heterogeneity within breast cancer subtypes by Cheung, Alison Min-Yan, Wang, Dan, Liu, Kela, Hope, Tyna, Murray, Mayan, Ginty, Fiona, Nofech-Mozes, Sharon, Martel, Anne Louise, Yaffe, Martin Joel

“…The extent of cellular heterogeneity in breast cancer could have potential impact on diagnosis and long-term outcome. However, pathology evaluation is limited…”
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Microultrasound Molecular Imaging of Vascular Endothelial Growth Factor Receptor 2 in a Mouse Model of Tumor Angiogenesis by Rychak, Joshua J., Graba, James, Cheung, Alison M.Y., Mystry, Bina S., Lindner, Jonathan R., Kerbel, Robert S., Foster, F. Stuart

“…High-frequency microultrasound imaging of tumor progression in mice enables noninvasive anatomic and functional imaging at excellent spatial and temporal…”
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Targeted anti-vascular endothelial growth factor receptor-2 therapy leads to short-term and long-term impairment of vascular function and increase in tumor hypoxia by FRANCO, Marcela, SHAN MAN, CHEN, Limor, EMMENEGGER, Urban, SHAKED, Yuval, CHEUNG, Alison M, BROWN, Allison S, HICKLIN, Daniel J, FOSTER, F. Stuart, KERBEL, Robert S

“…Because antiangiogenic therapies inhibit the growth of new tumor-associated blood vessels, as well as prune newly formed vasculature, they would be expected to…”
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Ki-67 Membranous Staining: Biologically Relevant or an Artifact of Multiplexed Immunofluorescent Staining by Wang, Dan, Pang, Zhengyu, Clarke, Gina M, Nofech-Mozes, Sharon, Liu, Kela, Cheung, Alison M Y, Filkins, Robert J, Yaffe, Martin J

“…In the process of developing a multiplex of 8 common breast cancer biomarkers (Her2/neu, estrogen receptor, progesterone receptor, Ki-67, aldehyde…”
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Detecting Vascular Changes in Tumour Xenografts Using Micro-Ultrasound and Micro-CT Following Treatment with VEGFR-2 Blocking Antibodies by Cheung, Alison M.Y, Brown, Allison S, Cucevic, Viviene, Roy, Marcia, Needles, Andrew, Yang, Victor, Hicklin, Daniel J, Kerbel, Robert S, Foster, F. Stuart

“…Abstract Blockade of vascular endothelial growth factor (VEGF) binding to its receptors on endothelial cells has been shown preclinically to induce tumour…”
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Chk2 Is a Tumor Suppressor That Regulates Apoptosis in both an Ataxia Telangiectasia Mutated (ATM)-Dependent and an ATM-Independent Manner by Hirao, Atsushi, Cheung, Alison, Duncan, Gordon, Girard, Pierre-Marie, Elia, Andrew J., Wakeham, Andrew, Okada, Hitoshi, Sarkissian, Talin, Wong, Jorge A., Sakai, Takashi, de Stanchina, Elisa, Bristow, Robert G., Suda, Toshio, Lowe, Scott W., Jeggo, Penny A., Elledge, Stephen J., Mak, Tak W.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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What's new in Shock, December 2011? by Cheung, Alison M, Jeschke, Marc G

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School-based research agenda on healthcare simulation for nursing education in Hong Kong by Wong, Suet Lai, Gill, Baljit Kaur, Chan, Jacky Hoi Man, Cheung, Alison Pui Han, Charm, Caroline Yee Chong, Fung, Carmen Ka Man, Lam, Ching Yee, Tong, Mavis Ying Ting, Lo, Cora Ka Yee, Tsang, Alan Yat Kwan, Nestel, Debra

“…BackgroundHealthcare simulation has been used as a pedagogical strategy in nursing education. Evidence has shown one of the positive impacts that simulations…”
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Brca2 deficiency does not impair mammary epithelium development but promotes mammary adenocarcinoma formation in p53+/- mutant mice by CHEUNG, Alison M. Y, ELIA, Andrew, TSAO, Ming-Sound, DONE, Susan, WAGNER, Kay-Uwe, HENNIGHAUSEN, Lothar, HAKEM, Razqallah, MAK, Tak W

“…Brca2 is an important tumor suppressor associated with susceptibility to breast cancer. Although increasing evidence indicates that the primary function of…”
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The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo by Sirard, C, de la Pompa, J L, Elia, A, Itie, A, Mirtsos, C, Cheung, A, Hahn, S, Wakeham, A, Schwartz, L, Kern, S E, Rossant, J, Mak, T W

“…Mutations in the SMAD4/DPC4 tumor suppressor gene, a key signal transducer in most TGFbeta-related pathways, are involved in 50% of pancreatic cancers…”
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Chk2 is dispensable for p53-mediated G1 arrest but is required for a latent p53-mediated apoptotic response by Jack, Melissa T, Woo, Richard A, Hirao, Atsushi, Cheung, Alison, Mak, Tak W, Lee, Patrick W K

“…In response to genotoxic stress, mammalian cells can activate cell cycle checkpoint pathways to arrest the cell for repair of DNA damage or induce apoptosis to…”
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PTEN in the haematopoietic system and its therapeutic indications by Cheung, Alison M., Mak, Tak W.

“…A unique feature of the haematopoietic system is its self-renewal ability while maintaining a stable number of pluripotent haematopoietic stem cells (HSCs)…”
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Interframe Clutter Filtering for High Frequency Flow Imaging by Needles, Andrew, Goertz, David E, Cheung, Alison M, Foster, F. Stuart

“…Abstract This study investigates ‘interframe’ clutter filtering with a high frequency (HF) flow imaging system with the objective of improving the performance…”
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Epithelial Ovarian Cancer: Providing Evidence of Predisposition Genes by Shah, Sidrah, Cheung, Alison, Kutka, Mikolaj, Sheriff, Matin, Boussios, Stergios

“…Epithelial ovarian cancer (EOC) is one of the cancers most influenced by hereditary factors. A fourth to a fifth of unselected EOC patients carry pathogenic…”
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Three-dimensional ultrasound biomicroscopy for xenograft growth analysis by Cheung, Alison M Y, Brown, Allison S, Hastie, Lauren A, Cucevic, Viviene, Roy, Marcia, Lacefield, James C, Fenster, Aaron, Foster, F Stuart

“…We reported the use of high-frequency ultrasound biomicroscopy (UBM) in the quantitative analysis of early tumor growth in mice bearing melanoma xenografts in…”
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Loss of Brca2 and p53 synergistically promotes genomic instability and deregulation of T-cell apoptosis by CHEUNG, Alison M. Y, PRAKASH HANDE, M, YOU-TEN, Annick, ELIA, Andrew, SQUIRE, Jeremy, BRISTOW, Rob, HAKEM, Razqallah, MAK, Tak W, JALALI, Farid, TSAO, Ming-Sound, SKINNIDER, Brian, HIRAO, Atsushi, MCPHERSON, J. Peter, KARASKOVA, Jana, SUZUKI, Akira, WAKEHAM, Andrew

“…BRCA2 is a breast cancer susceptibility gene of which the product is thought to be involved in monitoring genome integrity and cell cycle progression…”
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Non-Epithelial Ovarian Cancers: How Much Do We Really Know? by Cheung, Alison, Shah, Sidrah, Parker, Jack, Soor, Pavandeep, Limbu, Anu, Sheriff, Matin, Boussios, Stergios

“…Non-epithelial ovarian cancers (NEOC) are a group of uncommon malignancies that mainly includes germ cell tumours (GCT), sex cord-stromal tumours (SCST), and…”
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Abstract 2726: Characterization of immune microenvironment and heterogeneity in breast cancer subtypes by Jain, Drashti, Liao, Linda, Hopkins, Megan, Quintayo, Mary Anne, Talebian, Vida, Bayani, Jane, Cheung, Alison, Yaffe, Martin, Bartlett, John, Spears, Melanie

“…Despite ongoing advancements in the clinical management of breast cancer (BC), the variability in the response to treatment requires continued understanding of…”
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