Search Results - "Cheu, Ryan K."
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Translocated microbiome composition determines immunological outcome in treated HIV infection
Published in Cell (22-07-2021)“…The impact of the microbiome on HIV disease is widely acknowledged although the mechanisms downstream of fluctuations in microbial composition remain…”
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Quantitative modeling predicts mechanistic links between pre-treatment microbiome composition and metronidazole efficacy in bacterial vaginosis
Published in Nature communications (01-12-2020)“…Bacterial vaginosis is a condition associated with adverse reproductive outcomes and characterized by a shift from a Lactobacillus -dominant vaginal microbiota…”
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Impact of vaginal microbiome communities on HIV antiretroviral-based pre-exposure prophylaxis (PrEP) drug metabolism
Published in PLoS pathogens (01-12-2020)“…Despite the efficacy of antiretroviral-based pre-exposure prophylactics (PrEP) in men who have sex with men, studies in women have produced widely varying…”
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Increased mucosal neutrophil survival is associated with altered microbiota in HIV infection
Published in PLoS pathogens (11-04-2019)“…Gastrointestinal (GI) mucosal dysfunction predicts and likely contributes to non-infectious comorbidities and mortality in HIV infection and persists despite…”
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Altered Innate Immunity and Damaged Epithelial Integrity in Vaginal Microbial Dysbiosis
Published in Frontiers in reproductive health (13-07-2022)“…The role of neutrophils relative to vaginal dysbiosis is unclear. We hypothesize that bacterial vaginosis (BV)-associated bacteria may induce the activation…”
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Heavy Cannabis Use Associated With Reduction in Activated and Inflammatory Immune Cell Frequencies in Antiretroviral Therapy-Treated Human Immunodeficiency Virus-Infected Individuals
Published in Clinical infectious diseases (01-06-2018)“…Cannabis is a widely used drug in the United States, and the frequency of cannabis use in the human immunodeficiency virus (HIV)-infected population is…”
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