Search Results - "Chetia, Dipak"

Computational guided identification of a citrus flavonoid as potential inhibitor of SARS-CoV-2 main protease by Gogoi, Neelutpal, Chowdhury, Purvita, Goswami, Ashis Kumar, Das, Aparoop, Chetia, Dipak, Gogoi, Bhaskarjyoti

“…Although vaccine development is being undertaken at a breakneck speed, there is currently no effective antiviral drug for severe acute respiratory syndrome…”
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Novel series of 1,2,4-trioxane derivatives as antimalarial agents by Rudrapal, Mithun, Chetia, Dipak, Singh, Vineeta

“…Among three series of 1,2,4-trioxane derivatives, five compounds showed good in vitro antimalarial activity, three compounds of which exhibited better activity…”
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Identification of potential plant-based inhibitor against viral proteases of SARS-CoV-2 through molecular docking, MM-PBSA binding energy calculations and molecular dynamics simulation by Gogoi, Bhaskarjyoti, Chowdhury, Purvita, Goswami, Nabajyoti, Gogoi, Neelutpal, Naiya, Tufan, Chetia, Pankaj, Mahanta, Saurov, Chetia, Dipak, Tanti, Bhaben, Borah, Probodh, Handique, Pratap Jyoti

“…The Coronavirus disease 2019 (COVID-19), caused by the novel coronavirus, SARS-CoV-2, has recently emerged as a pandemic. Here, an attempt has been made…”
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In Vivo Validation of Folkloric Use of Costus pictus D. Don as Antidiabetic Plant in Assam, Using Streptozotocin Induced Wister Rat Model by Bhuyan, Biman, Chetia, Dipak

“…Costus pictus D. Don belonging to the family Costaceae is one of the most commonly used plant among traditional healers in the upper Assam region in India,…”
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Design, molecular docking, drug-likeness, and molecular dynamics studies of 1,2,4-trioxane derivatives as novel Plasmodium falciparum falcipain-2 (FP-2) inhibitors by Ghosh, Subham, Chetia, Dipak, Gogoi, Neelutpal, Rudrapal, Mithun

“…Despite significant progress made in drug discovery and development over the past few decades, malaria remains a life-threatening infectious disease across the…”
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Antiviral phytocompounds “ellagic acid” and “(+)-sesamin” of Bridelia retusa identified as potential inhibitors of SARS-CoV-2 3CL pro using extensive molecular docking, molecular dynamics simulation studies, binding free energy calculations, and bioactivity prediction by Umar, Abd. Kakhar, Zothantluanga, James H., Aswin, Keerthic, Maulana, Saipul, Sulaiman Zubair, Muhammad, Lalhlenmawia, H., Rudrapal, Mithun, Chetia, Dipak

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected billions and has killed millions to date. Studies are being carried out to find…”
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Integrated computational approach towards repurposing of antimalarial drug against SARS-CoV-2 main protease by Gogoi, Neelutpal, Chowdhury, Purvita, Goswami, Ashis Kumar, Das, Aparoop, Chetia, Dipak, Gogoi, Bhaskarjyoti

“…Huge vaccination drives are underway around the world for the ongoing COVID-19 pandemic. However, the search for antiviral drugs is equally crucial. As new…”
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In vitro antimalarial activity evaluation of two ethnomedicinal plants against chloroquine sensitive and resistant strains of Plasmodium falciparum by Gogoi, Neelutpal, Gogoi, Bhaskarjyoti, Chetia, Dipak

“…Background In this study, we selected two medicinal plants Citrus maxima (Burm.) Merr. and Artemisia nilagirica (C.B. Clarke) Pamp. on the basis of their…”
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Identification of bioactive molecules from Triphala (Ayurvedic herbal formulation) as potential inhibitors of SARS-CoV-2 main protease (Mpro) through computational investigations by Rudrapal, Mithun, Celik, Ismail, Khan, Johra, Ansari, Mohammad Azam, Alomary, Mohammad N., Alatawi, Fuad Abdullah, Yadav, Rohitash, Sharma, Tripti, Tallei, Trina Ekawati, Pasala, Praveen Kumar, Sahoo, Ranjan Kumar, Khairnar, Shubham J., Bendale, Atul R., Zothantluanga, James H., Chetia, Dipak, Walode, Sanjay G.

“…[Display omitted] Severe acute respiratory syndrome coronavirus disease (SARS-CoV-2) induced coronavirus disease 2019 (COVID-19) pandemic is the present…”
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A Simple Work-Up-free, Solvent-free Approach to Novel Amino Acid Linked 1,4-Disubstituted 1,2,3-Triazoles as Potent Antituberculosis Agents by Garg, Anirban, Borah, Debajit, Trivedi, Priyanka, Gogoi, Dipshikha, Chaliha, Amrita Kashyap, Ali, Abdul Aziz, Chetia, Dipak, Chaturvedi, Vinita, Sarma, Diganta

“…An efficient, green strategy for synthesis of 1,4-disubstituted-1,2,3-triazole has been developed using 1,8-diazabicyclo[5.4.0]­undec-7-ene (DBU) acetate ionic…”
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Characterization of potent antidiabetic compounds from Costus pictus D. Don found in Assam, India using in vitro in vivo methods by Biman Bhuyan, Dipak Chetia

“…ABSTRACT Objective: Costus pictus D. Don is a traditionally used plant in Naojan area of Golaghat district of Assam, India specifically for treating diabetes…”
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Computational guided identification of potential leads from Acacia pennata (L.) Willd. as inhibitors for cellular entry and viral replication of SARS-CoV-2 by Zothantluanga, James H., Gogoi, Neelutpal, Shakya, Anshul, Chetia, Dipak, Lalthanzara, H.

“…Background Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) started in 2019 and is still an on-going…”
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Molecular docking, synthesis and in vitro antimalarial evaluation of certain novel curcumin analogues by Dohutia, Chandrajit, Chetia, Dipak, Gogoi, Kabita, Bhattacharyya, Dibya Ranjan, Sarma, Kishore

“…The receptor protein PfATP6 has been identified as the common target of artemisinin and curcumin. The work was initiated to assess the antimalarial activity of…”
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Synthesis and antimalarial activity evaluation of 3-(3-(7-chloroquinolin-4-ylamino)propyl)-1,3-thiazinan-4-one derivatives by Kumawat, Mukesh Kumar, Singh, Udaya Pratap, Singh, Bhupendra, Prakash, Anil, Chetia, Dipak

“…Some novel derivatives of 3-(3-(7-chloroquinolin-4-ylamino)propyl)-1,3-thiazinan-4-one were synthesized and characterized by their physical and spectral data…”
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Synthesis, characterization and antimalarial activity of hybrid 4-aminoquinoline-1,3,5-triazine derivatives by Bhat, Hans Raj, Singh, Udaya Pratap, Yadav, Pankaj S., Kumar, Vikas, Gahtori, Prashant, Das, Aparoop, Chetia, Dipak, Prakash, Anil, Mahanta, J.

“…A novel series of hybrid 4-aminoquinolines-1,3,5-triazine were synthesized by means of aromatic nucleophilic displacement of chlorine atoms of…”
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Synthesis, antimalarial activity evaluation and molecular docking studies of some novel dispiro-1,2,4,5-tetraoxanes by Mukesh Kumar Kumawat, Dipak Chetia

“…Seven novel dispiro-1,2,4,5-tetraoxane derivatives were synthesized and characterized by a number of analytical and spectroscopic techniques. The molecules…”
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Synthesis and antimalarial activity study of some new Mannich bases of 7-chloro-4-aminoquinoline by Roy, Susanta, Chetia, Dipak, Rudrapal, Mithun, Prakash, Anil

“…New derivatives of 7-chloro-4-aminoquinoline Mannich base were prepared by selectively modifying the aliphatic diethyl amino function of isoquine with…”
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Identification of antimalarial phytoconstituents from Tinospora sinensis (Lour.) Merr. stem by in vitro whole cell assay and multiple targets directed in silico screening against Plasmodium falciparum by Gogoi, Neelutpal, Gogoi, Bhaskarjyoti, Kaishap, Partha Pratim, Chetia, Dipak

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Synthesis, Antimalarial Activity Evaluation and Molecular Docking Studies of Some New Substituted Spiro-1,2,4,5-Tetraoxane Derivatives by Kumawat, Mukesh Kumar, Chetia, Dipak

“…Eight new substituted spiro-1,2,4,5-tetraoxane derivatives were synthesized and characterized by a number of analytical and spectroscopic techniques. The…”
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Ruthenium(II)‐Catalyzed Synthesis of Spirobenzofuranones by a Decarbonylative Annulation Reaction by Kaishap, Partha P., Duarah, Gauri, Sarma, Bipul, Chetia, Dipak, Gogoi, Sanjib

“…The first decarbonylative insertion of an alkyne through C−H/C−C activation of six‐membered compounds is reported. The Ru‐catalyzed reaction of…”
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