Search Results - "Chestkov, I V"
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Patient-Specific Induced Pluripotent Stem Cells for SOD1-Associated Amyotrophic Lateral Sclerosis Pathogenesis Studies
Published in Actanaturae (01-01-2014)“…The genetic reprogramming technology allows one to generate pluripotent stem cells for individual patients. These cells, called induced pluripotent stem cells…”
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Abundance of ribosomal RNA gene copies in the genomes of schizophrenia patients
Published in Schizophrenia research (01-07-2018)“…The ribosome is a critical component of the translation machinery. The key component of ribosomes is ribosomal RNA (rRNA). Dysregulation of rRNA biogenesis has…”
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Quantification of cell-free DNA in blood plasma and DNA damage degree in lymphocytes to evaluate dysregulation of apoptosis in schizophrenia patients
Published in Journal of psychiatric research (01-04-2017)“…Abstract Oxidative DNA damage has been proposed as one of the causes of schizophrenia (SZ), and post mortem data indicate a dysregulation of apoptosis in SZ…”
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ROS-Induced DNA Damage Associates with Abundance of Mitochondrial DNA in White Blood Cells of the Untreated Schizophrenic Patients
Published in Oxidative medicine and cellular longevity (01-01-2018)“…Objective. The aim of this study was (1) to examine the leukocyte mtDNA copy number (CN) in unmedicated (SZ (m−)) and medicated (SZ (m+)) male patients with…”
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Molecular barriers to processes of genetic reprogramming and cell transformation
Published in Biochemistry (Moscow) (01-12-2014)“…Genetic reprogramming by ectopic expression of transcription factor genes induces the pluripotent state in somatic cells. This technology provides an…”
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Genetic cell reprogramming: A new technology for basic research and applied usage
Published in Russian journal of genetics (01-04-2015)“…Gene function disclosure and the development of modern technologies of genetic manipulations offered the possibility of genetic reprogramming application to…”
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A platform for studies of Huntington’s disease on the basis of induced pluripotent stem cells
Published in Annaly kliničeskoj i èksperimentalʹnoj nevrologii (Online) (01-02-2017)“…Huntingtons disease (HD) is one of the most severe hereditaryneurodegenerative disorders caused by CAG repeats expansionin the HTT gene. A recently elaborated…”
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Genetic Cell Reprogramming: A New Technology for Basic Research and Applied Usage
Published in Genetika (01-04-2015)“…Gene function disclosure and the development of modern technologies of genetic manipulations offered the possibility of genetic reprogramming application to…”
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