Search Results - "Chesney, Andrew D"
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SARS-COV-2 spike protein fragment eases amyloidogenesis of α-synuclein
Published in The Journal of chemical physics (07-07-2023)“…Parkinson's disease is accompanied by the presence of amyloids in the brain that are formed of α-synuclein chains. The correlation between COVID-19 and the…”
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Effect of an Amyloidogenic SARS-COV‑2 Protein Fragment on α‑Synuclein Monomers and Fibrils
Published in The journal of physical chemistry. B (26-05-2022)“…Aggregates of α-synuclein are thought to be the disease-causing agent in Parkinson’s disease. Various case studies have hinted at a correlation between…”
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Differential effects of SARS-CoV-2 amyloidogenic segments on the aggregation and toxicity of human islet amyloid polypeptide within membrane environments
Published in International journal of biological macromolecules (01-12-2024)“…Human islet amyloid polypeptide (hIAPP), an intrinsically disordered protein (IDP), plays a significant role in the pathogenesis of type 2 diabetes through its…”
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Human Amylin in the Presence of SARS-COV‑2 Protein Fragments
Published in ACS omega (04-04-2023)“…COVID-19 can lead to the onset of type-II diabetes, which is associated with the aggregation of islet amyloid polypeptides, also called amylin. Using molecular…”
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