Search Results - "Chesnaye, Nicholas C."

Results from the ERA-EDTA Registry indicate a high mortality due to COVID-19 in dialysis patients and kidney transplant recipients across Europe by Jager, Kitty J, Kramer, Anneke, Chesnaye, Nicholas C, Couchoud, Cécile, Sánchez-Álvarez, J Emilio, Garneata, Liliana, Collart, Fréderic, Hemmelder, Marc H, Ambühl, Patrice, Kerschbaum, Julia, Legeai, Camille, Del Pino Y Pino, María Dolores, Mircescu, Gabriel, Mazzoleni, Lionel, Hoekstra, Tiny, Winzeler, Rebecca, Mayer, Gert, Stel, Vianda S, Wanner, Christoph, Zoccali, Carmine, Massy, Ziad A

“…The aim of this study was to investigate 28-day mortality after COVID-19 diagnosis in the European kidney replacement therapy population. In addition, we…”
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Intention to treat and per protocol analysis in clinical trials by Tripepi, Giovanni, Chesnaye, Nicholas C., Dekker, Friedo W., Zoccali, Carmine, Jager, Kitty J.

“…In clinical epidemiology, experimental studies usually take the form of randomized controlled clinical trials (RCTs). The data analysis of an RCT can be…”
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An introduction to inverse probability of treatment weighting in observational research by Chesnaye, Nicholas C, Stel, Vianda S, Tripepi, Giovanni, Dekker, Friedo W, Fu, Edouard L, Zoccali, Carmine, Jager, Kitty J

“…ABSTRACT In this article we introduce the concept of inverse probability of treatment weighting (IPTW) and describe how this method can be applied to adjust…”
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Timing of dialysis initiation to reduce mortality and cardiovascular events in advanced chronic kidney disease: nationwide cohort study by Fu, Edouard L, Evans, Marie, Carrero, Juan-Jesus, Putter, Hein, Clase, Catherine M, Caskey, Fergus J, Szymczak, Maciej, Torino, Claudia, Chesnaye, Nicholas C, Jager, Kitty J, Wanner, Christoph, Dekker, Friedo W, van Diepen, Merel

“…To identify the optimal estimated glomerular filtration rate (eGFR) at which to initiate dialysis in people with advanced chronic kidney disease. Nationwide…”
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Symptom Burden before and after Dialysis Initiation in Older Patients by de Rooij, Esther N M, Meuleman, Yvette, de Fijter, Johan W, Jager, Kitty J, Chesnaye, Nicholas C, Evans, Marie, Caskey, Fergus J, Torino, Claudia, Porto, Gaetana, Szymczak, Maciej, Drechsler, Christiane, Wanner, Christoph, Dekker, Friedo W, Hoogeveen, Ellen K

“…For older patients with kidney failure, lowering symptom burden may be more important than prolonging life. Dialysis initiation may affect individual kidney…”
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Mortality risk disparities in children receiving chronic renal replacement therapy for the treatment of end-stage renal disease across Europe: an ESPN-ERA/EDTA registry analysis by Chesnaye, Nicholas C, MSc, Schaefer, Franz, Prof, Bonthuis, Marjolein, PhD, Holman, Rebecca, PhD, Baiko, Sergey, PhD, Baskın, Esra, MD, Bjerre, Anna, PhD, Cloarec, Sylvie, MD, Cornelissen, Elisabeth A M, PhD, Espinosa, Laura, MD, Heaf, James, DMSc, Stone, Rosário, MD, Shtiza, Diamant, PhD, Zagozdzon, Ilona, PhD, Harambat, Jérôme, Prof, Jager, Kitty J, Prof, Groothoff, Jaap W, MD, van Stralen, Karlijn J, PhD

“…Summary Background We explored the variation in country mortality rates in the paediatric population receiving renal replacement therapy across Europe, and…”
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Converting from face-to-face to postal follow-up and its effects on participant retention, response rates and errors: lessons from the EQUAL study in the UK by Gates, Emer, Hole, Barnaby, Hayward, Samantha, Chesnaye, Nicholas C, Meuleman, Yvette, Dekker, Friedo W, Evans, Marie, Heimburger, Olof, Torino, Claudia, Porto, Gaetana, Szymczak, Maciej, Drechsler, Christiane, Wanner, Christoph, Jager, Kitty J, Roderick, Paul, Caskey, Fergus

“…Prospective cohort studies are challenging to deliver, with one of the main difficulties lying in retention of participants. The need to socially distance…”
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Protein Biomarkers and Major Cardiovascular Events in Older People With Advanced CKD: The European Quality (EQUAL) Study by Hayward, Samantha J L, Chesnaye, Nicholas C, Hole, Barnaby, Aylward, Ryan, Meuleman, Yvette, Torino, Claudia, Porto, Gaetana, Szymczak, Maciej, Drechsler, Christiane, Dekker, Friedo W, Evans, Marie, Jager, Kitty J, Wanner, Christoph, Caskey, Fergus J

“…Cardiovascular disease is the leading cause of morbidity and mortality in chronic kidney disease (CKD). We investigated 184 inflammatory and cardiovascular…”
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Where to look for the most frequent biases? by Jager, Kitty J., Tripepi, Giovanni, Chesnaye, Nicholas C., Dekker, Friedo W., Zoccali, Carmine, Stel, Vianda S.

“…Study quality depends on a number of factors, one of them being internal validity. Such validity can be affected by random and systematic error, the latter…”
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Non-linear relationships in clinical research by Chesnaye, Nicholas C, van Diepen, Merel, Dekker, Friedo, Zoccali, Carmine, Jager, Kitty J, Stel, Vianda S

“…True linear relationships are rare in clinical data. Despite this, linearity is often assumed during analyses, leading to potentially biased estimates and…”
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Differences in the epidemiology, management and outcomes of kidney disease in men and women by Chesnaye, Nicholas C., Carrero, Juan Jesus, Hecking, Manfred, Jager, Kitty J.

“…Improved understanding of differences in kidney disease epidemiology, management and outcomes in men and women could help nephrologists to better meet the…”
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The impact of population ageing on the burden of chronic kidney disease by Chesnaye, Nicholas C., Ortiz, Alberto, Zoccali, Carmine, Stel, Vianda S., Jager, Kitty J.

“…The burden of chronic kidney disease (CKD) and its risk factors are projected to rise in parallel with the rapidly ageing global population. By 2050, the…”
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Mortality risk in European children with end-stage renal disease on dialysis by Chesnaye, Nicholas C, Schaefer, Franz, Groothoff, Jaap W, Bonthuis, Marjolein, Reusz, György, Heaf, James G, Lewis, Malcolm, Maurer, Elisabeth, Paripović, Dušan, Zagozdzon, Ilona, van Stralen, Karlijn J, Jager, Kitty J

“…We aimed to describe survival in European pediatric dialysis patients and compare the differential mortality risk between patients starting on hemodialysis…”
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Renal function decline in older men and women with advanced chronic kidney disease—results from the EQUAL study by Chesnaye, Nicholas C, Dekker, Friedo W, Evans, Marie, Caskey, Fergus J, Torino, Claudia, Postorino, Maurizio, Szymczak, Maciej, Ramspek, Chava L, Drechsler, Christiane, Wanner, Christoph, Jager, Kitty J

“…Abstract Introduction Understanding the mechanisms underlying the differences in renal decline between men and women may improve sex-specific clinical…”
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Work status and work ability of patients receiving kidney replacement therapy: results from a European survey by de Jong, Rianne W, Boezeman, Edwin J, Chesnaye, Nicholas C, Bemelman, Frederike J, Massy, Ziad A, Jager, Kitty J, Stel, Vianda S, de Boer, Angela G E M

“…ABSTRACT Background Employment is important for the quality of life and financial security of patients of working age receiving kidney replacement therapy…”
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Machine learning models for predicting acute kidney injury: a systematic review and critical appraisal by Vagliano, Iacopo, Chesnaye, Nicholas C, Leopold, Jan Hendrik, Jager, Kitty J, Abu-Hanna, Ameen, Schut, Martijn C

“…Background The number of studies applying machine learning (ML) to predict acute kidney injury (AKI) has grown steadily over the past decade. We assess and…”
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Survival in children requiring chronic renal replacement therapy by Chesnaye, Nicholas C., van Stralen, Karlijn J., Bonthuis, Marjolein, Harambat, Jérôme, Groothoff, Jaap W., Jager, Kitty J.

“…Survival in the pediatric end-stage renal disease (ESRD) population has improved substantially over recent decades. Nonetheless, mortality remains at least 30…”
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Sex and gender disparities in the epidemiology and outcomes of chronic kidney disease by Carrero, Juan Jesus, Hecking, Manfred, Chesnaye, Nicholas C., Jager, Kitty J.

“…Key Points The proportion of women with predialysis chronic kidney disease (CKD) is higher than that of men; this difference is likely due to the longer life…”
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International prescribing patterns and polypharmacy in older people with advanced chronic kidney disease: results from the European Quality study by Hayward, Samantha, Hole, Barnaby, Denholm, Rachel, Duncan, Polly, Morris, James E, Fraser, Simon D S, Payne, Rupert A, Roderick, Paul, Chesnaye, Nicholas C, Wanner, Christoph, Drechsler, Christiane, Postorino, Maurizio, Porto, Gaetana, Szymczak, Maciej, Evans, Marie, Dekker, Friedo W, Jager, Kitty J, Caskey, Fergus J

“…Abstract Background People with chronic kidney disease (CKD) are at high risk of polypharmacy. However, no previous study has investigated international…”
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The association between TMAO, CMPF, and clinical outcomes in advanced chronic kidney disease: results from the European QUALity (EQUAL) Study by Dai, Lu, Massy, Ziad A, Stenvinkel, Peter, Chesnaye, Nicholas C, Larabi, Islam Amine, Alvarez, Jean Claude, Caskey, Fergus J, Torino, Claudia, Porto, Gaetana, Szymczak, Maciej, Krajewska, Magdalena, Drechsler, Christiane, Wanner, Christoph, Jager, Kitty J, Dekker, Friedo W, Evenepoel, Pieter, Evans, Marie

“…Trimethylamine N-oxide (TMAO), a metabolite from red meat and fish consumption, plays a role in promoting cardiovascular events. However, data regarding TMAO…”
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