Search Results - "Chervo, María F."
-
1
Blockade of Stat3 oncogene addiction induces cellular senescence and reveals a cell-nonautonomous activity suitable for cancer immunotherapy
Published in Oncoimmunology (01-01-2020)“…Stat3 is constitutively activated in several tumor types and plays an essential role in maintaining their malignant phenotype and immunosupression. To take…”
Get full text
Journal Article -
2
Correction: Halting ErbB-2 isoforms retrograde transport to the nucleus as a new theragnostic approach for triple-negative breast cancer
Published in Cell death & disease (15-12-2023)Get full text
Journal Article -
3
Canonical ErbB-2 isoform and ErbB-2 variant c located in the nucleus drive triple negative breast cancer growth
Published in Oncogene (24-09-2020)“…Triple negative breast cancer (TNBC) refers to tumors that do not express clinically significant levels of estrogen and progesterone receptors, and lack…”
Get full text
Journal Article -
4
Halting ErbB-2 isoforms retrograde transport to the nucleus as a new theragnostic approach for triple-negative breast cancer
Published in Cell death & disease (09-05-2022)“…Triple-negative breast cancer (TNBC) is clinically defined by the absence of estrogen and progesterone receptors and the lack of membrane overexpression or…”
Get full text
Journal Article -
5
Nuclear ErbB-2: a Novel Therapeutic Target in ErbB-2-Positive Breast Cancer?
Published in Hormones & cancer (01-06-2019)“…Membrane overexpression of ErbB-2 (MErbB-2), a member of the ErbB family of receptor tyrosine kinases, occurs in 15–20% of breast cancers (BC) and constitutes…”
Get full text
Journal Article -
6
Nuclear PDCD4 Expression Defines a Subset of Luminal B-Like Breast Cancers with Good Prognosis
Published in Hormones & cancer (01-10-2020)“…The hormone receptor-positive (estrogen and/or progesterone receptor (PR)-positive) and HER2-negative breast cancer (BC) subtype is a biologically…”
Get full text
Journal Article -
7
ErbB-2 nuclear function in breast cancer growth, metastasis and resistance to therapy
Published in Endocrine-related cancer (01-12-2016)“…Approximately 15–20% of breast cancers (BC) show either membrane overexpression of ErbB-2 (MErbB-2), a member of the ErbBs family of receptor tyrosine kinases,…”
Get full text
Journal Article -
8
ODP571 Blockade of ErbB-2 Nuclear Function Induces the Interferon Signaling Pathway in Breast Cancer Models Resistant to Trastuzumab
Published in Journal of the Endocrine Society (01-11-2022)“…Abstract ErbB-2, a member of ErbB family of receptor tyrosine kinases, is a key oncogenic driver in breast cancer. Despite clinical efficiency of…”
Get full text
Journal Article -
9
Androgen Receptor Highjacks ErbB-2 Nuclear Function to Induce Triple Negative Breast Cancer Growth
Published in Journal of the Endocrine Society (03-05-2021)“…Abstract Triple negative breast cancer (TNBC) has poor prognosis and neither established biomarkers nor therapeutic targets. On the one hand the androgen…”
Get full text
Journal Article -
10
Abstract 2265: Stat3 and ErbB-2 interaction in breast cancer metastasis
Published in Cancer research (Chicago, Ill.) (01-08-2015)“…Abstract Metastasis is a complex multistep process, responsible for as much as 90% of cancer-related deaths, yet obtaining successful treatment for these…”
Get full text
Journal Article -
11
SUN-122 Nuclear PDCD4 Expression Predicts Good Clinical Outcome in Luminal A-Like and Luminal B-Like Breast Cancer Subtypes
Published in Journal of the Endocrine Society (08-05-2020)“…Abstract Hormone receptor-positive (HR+, estrogen and/or progesterone receptor-positive) and HER2-negative breast cancer (BC) subtype is a biologically…”
Get full text
Journal Article -
12
Abstract 1558: Deciphering the role of ribosomal paralogs RPL39/RPL39L in metaplastic breast cancer
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Metaplastic breast cancer (MpBC) is a rare, highly aggressive, and metastatic malignancy that accounts for <5% of all breast cancer diagnoses. Most…”
Get full text
Journal Article -
13
Abstract 344: Blockade of retrograde transport in triple negative breast cancer excludes ErbB-2 isoforms from the nucleus and abrogates tumor growth
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Abstract Triple negative breast cancer (TNBC) is clinically defined by the absence of estrogen and progesterone receptors and the lack of membrane…”
Get full text
Journal Article -
14
Nuclear ErbB-2-Induced Transcriptome Drives Triple Negative Breast Cancer Growth
Published in Journal of the Endocrine Society (03-05-2021)“…Abstract Triple negative breast cancer (TNBC) refers to tumors that do not express clinically significant levels of estrogen and progesterone receptors, and…”
Get full text
Journal Article