Search Results - "Cherukommu, Shirisha"
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BODIPY-based Ru(II) and Ir(III) organometallic complexes of avobenzone, a sunscreen material: Potent anticancer agents
Published in Journal of inorganic biochemistry (01-12-2018)“…The use of organic compounds with known medicinal properties in the synthesis of metal-based complexes is an important alternative to improve the biological…”
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A Virtual Screening Approach for the Identification of High Affinity Small Molecules Targeting BCR-ABL1 Inhibitors for the Treatment of Chronic Myeloid Leukemia
Published in Current topics in medicinal chemistry (01-01-2017)“…CML originates due to reciprocal translocation in Philadelphia chromosome leading to the formation of fusion product BCR-ABL which constitutively activates…”
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Synthesis of DNA interactive C3-trans-cinnamide linked β-carboline conjugates as potential cytotoxic and DNA topoisomerase I inhibitors
Published in Bioorganic & medicinal chemistry (15-09-2018)“…[Display omitted] •New C3-trans-cinnamide linked β-carboline conjugates were synthesized.•Compounds 8v and 8x showed potent in vitro activity (nM) on MCF-7…”
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In Vitro and In Vivo Demonstration of Human-Ovarian-Cancer Necrosis through a Water-Soluble and Near-Infrared-Absorbing Chlorin
Published in Journal of medicinal chemistry (14-06-2018)“…With the objective of developing efficient sensitizers for therapeutic applications, we synthesized a water-soluble…”
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