Search Results - "Chernyshenko, V. O."

Limited Proteolysis of Fibrinogen by Fibrinogenase from Echis multisquamatis Venom by Chernyshenko, V. O.

“…Previously we purified fibrinogenase from venom of Echis multisquamatis and showed that the enzyme predominantly cleaves BβArg42-Ala43 peptide bond of…”
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Men of the molecules by Chernyshenko, V. O.

“…In memoriam Eduard Lugovskoi and Russell Doolittle we are referring to several episodes of their life and work. Russell Doolittle an American biochemist and…”
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MOLECULAR MECHANISMS OF INTRAVASCULAR INHIBITION AND STIMULATION OF EXTRAVASCULAR THROMBOSIS by Chernyshenko, V. O

“…The hemostasis system is designed to maintain a balance between the processes of blood clotting, anticoagulation, as well as fibrinolysis, to ensure constant…”
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Validation of the diagnostics algorithm to monitor coagulation parameters in pregnant women by Korolova, D. S., Pavlenko, A. O., Altorjay, A., Zhuk, S. I., Us, I. V., Tsaryk, Y., Suranyi, A., Chernyshenko, V. O.

“…Thrombotic events are among the most dangerous complications of pregnancy. Therefore, selection of appropriate tests and standardization of techniques used for…”
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Chelidonium majus WATER EXTRACT INITIATES PLATELET AGGREGATION AND INHIBITS FIBRIN POLYMERIZATION IN BLOOD PLASMA by Marunych, R. Yu

“…Chelidonium majus is a well-known source of biologically active compounds. Most of them are alkaloids, which are used in researches and for tradition medicine…”
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OPTIMIZATION OF THE EVALUATION METHOD OF THE PERFORMANCE OF THERAPY USING INDIRECT ACTION ANTICOAGULANTS by Korolova, D. S.

“…Aim. Treatment by indirect anticoagulants (vitamin K antagonists) requires a personalized approach for controlling the overall level of prothrombin and the…”
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Evaluation of biochemical indicators in blood plasma of rats with tetracycline-induced hepatosis and their correction by milk phospholipids by Gryshchenko, V. A., Musiychuk, V. V., Chernyshenko, V. O., Gornytska, O. V., Platonova, T. M.

“…Tetracycline is a drug with direct cytotoxic action on the liver, and therefore it is widely used in pharmaceutical studies of therapeutic effectiveness of…”
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Thromboelastographic study of fibrin clot and molecular basis of maximum clot firmness by Korolova, D. S., Stohnii, Y. M., Gryshchuk, V. I., Zhuk, S. I., Us, I. V., Chernyshenko, T. M., Kostiuchenko, O. P., Klymenko, K. P., Platonov, O. M., Ivashchenko, O. I., Chernyshenko, V. O.

“…Maximum clot firmness (MCF) is the main parameter of thromboelastography (TEG) reflecting the stability of a clot. In this work, we looked for markers that can…”
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Functional properties of individual sub-domains of the fibrin(ogen) αC-domains by Stohnii, Y.M., Yatsenko, T.A., Nikulina, V.V., Kucheriavyi, Y.P., Hrabovskyi, O.O., Slominskyi, O.Yu, Savchenko, K.S., Garmanchuk, L.V., Varbanets, L.D., Tykhomyrov, A.O., Chernyshenko, V.O.

“…•The use of specific proteases allowed us to obtain truncated forms of fibrin(ogen) lacking its C-terminal sub-domains or both N- and C-terminal sub-domains of…”
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Novel monoclonal antibody to fibrin(ogen) αC-region for detection of the earliest forms of soluble fibrin by N. E. Lugovska, I. M. Kolesnikova, Ye. M. Stohnii, V. O. Chernyshenko, A. V. Rebriev, O. P. Kostiuchenko, G .K. Gogolinska, N. A. Dziubliuk, L. D. Varbanets, T. M. Platonova, S. V. Komisarenko

“…Obtaining new monoclonal antibodies (mAbs) towards fibrin(ogen) and its fragments is an important task for studying mechanisms of blood clot formation,…”
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Isolation and purification of Bacillus thuringiensis var. israelensis IМV В-7465 peptidase with specificity toward elastin and collagen by Nidialkova, N A, Varbanets, L D, Chernyshenko, V O

“…Peptidase of Bacillus thuringiensis var. israelensis IМV В-7465 was isolated from culture supernatant using consecutive fractionations by an ammonium sulphate…”
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METALLOPROTEASE FROM THE CULTURAL LIQUID OF Pleurotus osreatus by Sakovich, V. V.

“…The aim of this work was to identify and to study physical and chemical properties of the enzyme preparation which was obtained from the cultural liquid of…”
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Blood coagulation and aortic wall integrity in rats with obesity-induced insulin resistance by Dziuba, O. S.

“…Obesity is an important factor in pathogenesis of disorders caused by chronic inflammation. Diet-induced obesity leads to dyslipidemia and insulin resistance…”
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Haemostasis modulation by calix[4]arene methylenebisphosphonic acid C-145 and its sulfur-containing analogue by Chernyshenko, V. O., Savchuk, O. V., Cherenok, S. O., Silenko, O. M., Negelia, A. O.

“…C-145 (octasodium salt of calix[4]arene-tetra-methylenebisphosphonic acid) was previously considered as specific anti-сoagulant agent that affects fibrin…”
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Mapping of residues of fibrinogen cleaved by protease II of Bacillus thuringiensis var. israelensis IMV B-7465 by E. M. Stohniy, V. O. Chernyshenko, N. A. Nidialkova, A. V. Rebriev, L. D. Varbanets, V. E. Hadzhynova, T. M. Chernyshenko, I. M. Kolesnikova, E. V. Lugovskoy

“…The limited proteolysis of macromolecules allows obtaining the fragments that preserve the structure and functional properties of the whole molecule and could…”
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CALIX[4]ARENE C-145 EFFECTS ON СELLULAR HAEMOSTASIS by Chernyshenko, V. O.

“…The aim of the research was to study a potential antithrombotic sodium salt of calix[4]arene-methylene-bis-phosphonic acid (С-145) — on activation and…”
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ACTION OF HIGH-DISPERSED SILICA ON BLOOD COAGULATION FACTORS ACTIVATION by Chernyshenko, T M, Gryshchuk, V I, Galagan, N P, Chernyshenko, V O, Gornytska, O V, Platonova, T M, Lugovskoy, E V

“…Using of high-dispersed silica based sorbents is a new and prospective method of bleeding arrest. Studies of high-dispersed silica haemostatic action during…”
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MOLECULAR MECHANISMS OF INHIBITION OF INTRAVASCULAR, AND ACTIVATION OF EXTRAVASCULAR THROMBUS FORMATION by Chernyshenko, V O, Lugovska, N E

“…Система гемостазу покликана пщтримувати баланс мт процесами зсщання KpoBİ, антикоагуляци, а також ф^ринолту, забезпечувати постшний ефективний кровообт в…”
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LIMITED PROTEOLYSIS OF FIBRINOGEN BY PROTEASE OF Gloydius halys halys SNAKE VENOM by Stohnii, Ye. M.

“…Aim. One of the approaches for studying structure and functions of proteins is their limited proteolysis. Proteolytic fragments of macromolecules can preserve…”
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DIRECTED PROTEOLYSIS OF FIBRINOGEN BY PROTEASE OF Gloydius halys halys VENOM by Stohnii, Ye M, Rebriev, A V, Hornytska, O V, Slominskiy, O Yu, Kostiuchenko, O P, Klymenko, K P, Chernyshenko, V O

“…Мета. Одним İ3 пiдходiв до вивчення структури та функци npoTeÍHÍB e Íx обмежений протеол^. Отриманi шляхом гiдролiзу фрагменти протеМв також можуть мати…”
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