Search Results - "Chernyavsky, Igor L"
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Blood Flow and Transport in the Human Placenta
Published in Annual review of fluid mechanics (05-01-2019)“…The placenta is a multifunctional organ that exchanges blood gases and nutrients between a mother and her developing fetus. In humans, fetal blood flows…”
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2
Image-Based Modeling of Blood Flow and Oxygen Transfer in Feto-Placental Capillaries
Published in PloS one (27-10-2016)“…During pregnancy, oxygen diffuses from maternal to fetal blood through villous trees in the placenta. In this paper, we simulate blood flow and oxygen transfer…”
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3
In vitro , in silico and in vivo study challenges the impact of bronchial thermoplasty on acute airway smooth muscle mass loss
Published in The European respiratory journal (01-05-2018)“…Bronchial thermoplasty is a treatment for asthma. It is currently unclear whether its histopathological impact is sufficiently explained by the proportion of…”
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Quantifying the impact of tissue metabolism on solute transport in feto-placental microvascular networks
Published in Interface focus (06-10-2019)“…The primary exchange units in the human placenta are terminal villi, in which fetal capillary networks are surrounded by a thin layer of villous tissue,…”
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5
The role of inflammation resolution speed in airway smooth muscle mass accumulation in asthma: insight from a theoretical model
Published in PloS one (14-03-2014)“…Despite a large amount of in vitro data, the dynamics of airway smooth muscle (ASM) mass increase in the airways of patients with asthma is not well…”
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6
Transport in the placenta: homogenizing haemodynamics in a disordered medium
Published in Philosophical transactions of the Royal Society of London. Series A: Mathematical, physical, and engineering sciences (13-11-2011)“…The placenta is an essential component of the life-support system for the developing foetus, enabling nutrients and waste to be exchanged between the foetal…”
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Human placental oxygenation in late gestation: experimental and theoretical approaches
Published in The Journal of physiology (01-12-2018)“…The placenta is crucial for life. It is an ephemeral but complex organ acting as the barrier interface between maternal and fetal circulations, providing…”
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8
Physical and geometric determinants of transport in fetoplacental microvascular networks
Published in Science advances (01-04-2019)“…Across mammalian species, solute exchange takes place in complex microvascular networks. In the human placenta, the primary exchange units are terminal villi…”
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9
Red blood cell dynamics in extravascular biological tissues modelled as canonical disordered porous media
Published in Interface focus (14-10-2022)“…The dynamics of blood flow in the smallest vessels and passages of the human body, where the cellular character of blood becomes prominent, plays a dominant…”
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Comment on "Unraveling a Clinical Paradox: Why Does Bronchial Thermoplasty Work in Asthma?"
Published in American journal of respiratory cell and molecular biology (01-11-2019)“…The authors argue on the effectiveness of bronchial thermoplasty (BT) in asthma. Here, presents caution when interpreting predictions of computational models…”
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11
Characterizing the multiscale structure of fluctuations of transported quantities in a disordered medium
Published in IMA journal of applied mathematics (01-10-2012)“…The transport of a scalar quantity in a disordered medium is a common problem in science and engineering. To understand the interplay between deterministic…”
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12
A functional exchange 'shunt' in the umbilical cord: the role of coiling structure in solute and heat transfer
Published in Placenta (Eastbourne) (07-09-2023)Get full text
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13
Micro-haemodynamics at the maternal–fetal interface: Experimental, theoretical and clinical perspectives
Published in Current opinion in biomedical engineering (01-06-2022)“…The placenta is a vital interface between the mother and her developing fetus. Micro-haemodynamics of the placenta, where the particulate nature of blood flow…”
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14
Advection-dominated transport past isolated disordered sinks: stepping beyond homogenization
Published 13-04-2022“…Proc. R. Soc. A 478:20220032 (2022) We investigate the transport of a solute past isolated sinks in a bounded domain when advection is dominant over diffusion,…”
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15
A multiscale analysis of flow and transport in the human placenta
Published 01-01-2011“…The human placenta is characterised by a unique circulatory arrangement, with numerous villous trees containing fetal vessels immersed in maternal blood…”
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Dissertation -
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Quantifying the impact of tissue metabolism on solute transport in feto-placental microvascular networks
Published 21-05-2019“…Interface Focus 9 (2019) 20190021 The primary exchange units in the human placenta are terminal villi, in which fetal capillary networks are surrounded by a…”
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17
Physical and geometric determinants of transport in feto-placental microvascular networks
Published 12-02-2019“…Science Advances 5 (2019) eaav6326 Across mammalian species, solute exchange takes place in complex microvascular networks. In the human placenta, the primary…”
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Journal Article -
18
Image-Based Modeling of Blood Flow and Oxygen Transfer in Feto-Placental Capillaries
Published 27-10-2016“…PLoS ONE 11(10):e0165369 (2016) During pregnancy, oxygen diffuses from maternal to fetal blood through villous trees in the placenta. In this paper, we…”
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19
Mathematical model for blood flow autoregulation by endothelium-derived relaxing factor
Published 24-04-2006“…The fluid shear stress is an important regulator of the cardiovascular system via the endothelium-derived relaxing factor (EDRF) that is Nitric Oxide. This…”
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